Compile Data Set for Download or QSAR
maximum 50k data
Found 19 of ic50 for monomerid = 50042949
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)TBA
LigandPNGBDBM50042949((E)-1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl...)
Affinity DataIC50:  4.60nMAssay Description:Inhibition of 5-lipoxygenase in rat RBL1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)TBA
LigandPNGBDBM50042949((E)-1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl...)
Affinity DataIC50:  4.60nMAssay Description:In vitro inhibition against 5-lipoxygenase in RBL-1 cells was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)TBA
LigandPNGBDBM50042949((E)-1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl...)
Affinity DataIC50:  450nMAssay Description:Inhibition of Rattus norvegicus (rat) lens aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
University Of Calabria

Curated by ChEMBL
LigandPNGBDBM50042949((E)-1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl...)
Affinity DataIC50:  730nMAssay Description:Inhibition of ACE in rabbit lung assessed as decrease in dansylglycine concentration after 5 mins by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Northern Kentucky University

Curated by ChEMBL
LigandPNGBDBM50042949((E)-1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of bovine xanthine oxidase assessed as conversion of xanthine to uric acid by spectroscopic analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Shanghai Institute of Material Medica, Chinese Academy of Sciences

LigandPNGBDBM50042949((E)-1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl...)
Affinity DataIC50:  2.37E+3nMpH: 4.5 T: 2°CAssay Description:The assay based on fluorescenceresonance energy transfer was carried out with BACE1 enzyme at pH 4.5 with a substrate, H-Lys(DABSYL)-SEVNLDAEFR-Gin-(...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
National Cheng Kung University

Curated by ChEMBL
LigandPNGBDBM50042949((E)-1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl...)
Affinity DataIC50:  6.40E+3nMAssay Description:Inhibition of PI3Kalpha (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
University Of Basel

Curated by ChEMBL
LigandPNGBDBM50042949((E)-1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl...)
Affinity DataIC50:  7.30E+3nMAssay Description:Inhibition of human 17beta-HSD2 expressed in HEK293 cell lysates incubated for 10 mins using [2,4,6,7-3H]-estradiol and NAD+ by scintillation countin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM50042949((E)-1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-acyl-carrier protein reductase(Plasmodium falciparum)
National Institute Of Immunology

Curated by ChEMBL
LigandPNGBDBM50042949((E)-1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl...)
Affinity DataIC50:  1.25E+4nMAssay Description:Inhibition of Plasmodium falciparum ENRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM50042949((E)-1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl...)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50042949((E)-1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibitory activity against HIV-1 Integrase (HIV-1-IN)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50042949((E)-1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl...)
Affinity DataIC50:  2.00E+4nMAssay Description:Compound concentration required to reduce HIV-1 Integrase 3'-processing activity by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH] FabI(Escherichia coli)
National Institute Of Immunology

Curated by ChEMBL
LigandPNGBDBM50042949((E)-1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of Escherichia coli ENRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Institute For Biochemistry

Curated by ChEMBL
LigandPNGBDBM50042949((E)-1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl...)
Affinity DataIC50:  6.50E+4nMAssay Description:Inhibition of p60 c-SrcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Institute For Biochemistry

Curated by ChEMBL
LigandPNGBDBM50042949((E)-1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl...)
Affinity DataIC50:  6.50E+4nMAssay Description:Inhibition of c-SrcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(Homo sapiens (Human))
Tokushima Bunri University

Curated by ChEMBL
LigandPNGBDBM50042949((E)-1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl...)
Affinity DataIC50:  1.20E+5nMAssay Description:Inhibition of Prostaglandin G/H synthase activity in sheep seminal vesicle was determined 100 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
University Of Calabria

Curated by ChEMBL
LigandPNGBDBM50042949((E)-1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl...)
Affinity DataIC50:  7.30E+5nMAssay Description:Inhibition of rabbit lung ACE assessed as reduction in hippuryl-histidyl-leucine substrate by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
University Of Calabria

Curated by ChEMBL
LigandPNGBDBM50042949((E)-1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl...)
Affinity DataIC50:  7.30E+8nMAssay Description:Inhibition of rabbit lung ACE assessed as inhibition of hippuryl-histidyl-leucine substrate hydrolysis pretreated for 10 mins followed by addition of...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed