TargetProtein kinase C alpha type(Bos taurus (bovine))
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Ability to displace bound [20-3H]-PDBU from a recombinant single isozyme (PKCalpha) in the presence of phosphatidylserineMore data for this Ligand-Target Pair
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Bethesda
Curated by ChEMBL
National Cancer Institute-Bethesda
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Binding Affinity against protein kinase C alphaMore data for this Ligand-Target Pair
Affinity DataKi: 0.330nMAssay Description:Displacement of [3H]PDBu from mouse wild type C1b domain of PKCdelta expressed in Escherichia coliMore data for this Ligand-Target Pair
Affinity DataKi: 0.351nMAssay Description:Displacement of [3H]PDBu from protein kinase C delta C1b domain (Wild type)More data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Inhibition of [3H]- PDBu binding to peptide D of mouse skin Protein kinase C etaMore data for this Ligand-Target Pair
TargetProtein kinase C delta type(Homo sapiens (Human))
Georgetown University Medical Center
Curated by ChEMBL
Georgetown University Medical Center
Curated by ChEMBL
Affinity DataKi: 0.800nMAssay Description:Inhibition of [3H]-PDBu binding to PKC delta wild typeMore data for this Ligand-Target Pair
Affinity DataKi: 0.820nMAssay Description:Displacement of [3H]PDBu from protein kinase C delta C1b domain mutant (F13G)More data for this Ligand-Target Pair
Affinity DataKi: 0.950nMAssay Description:Displacement of 3[H]PDBu from Protein kinase C eta C1b domainMore data for this Ligand-Target Pair
TargetProtein kinase C delta type(Homo sapiens (Human))
Georgetown University Medical Center
Curated by ChEMBL
Georgetown University Medical Center
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Displacement of 3[H]PDBu from Protein kinase C delta C1a domainMore data for this Ligand-Target Pair
Affinity DataKi: 1.24nMAssay Description:Displacement of [3H]PDBu from protein kinase C delta C1b domain mutant (T12G)More data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Displacement of 3[H]PDBu from Protein kinase C epsilon C1b domainMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Displacement of 3[H]PDBu from Protein kinase C theta C1b domainMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Displacement of 3[H]PDBu from Protein kinase C eta C1a domainMore data for this Ligand-Target Pair
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Bethesda
Curated by ChEMBL
National Cancer Institute-Bethesda
Curated by ChEMBL
Affinity DataKi: 1.60nMAssay Description:Displacement of 3[H]PDBu from Protein kinase C alpha C1a domainMore data for this Ligand-Target Pair
Affinity DataKi: 1.80nMAssay Description:Displacement of 3[H]PDBu from Protein kinase C epsilon C1a domainMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Displacement of 3[H]PDBu from Protein kinase C beta C1a domainMore data for this Ligand-Target Pair
Affinity DataKi: 2.90nMAssay Description:Displacement of 3[H]PDBu from Protein kinase C gamma C1a domainMore data for this Ligand-Target Pair
Affinity DataKi: 6.20nMAssay Description:Displacement of [3H]PDBu from mouse PKCdelta C1b Q27E mutant expressed in Escherichia coliMore data for this Ligand-Target Pair
Affinity DataKi: 6.59nMAssay Description:Displacement of [3H]PDBu from protein kinase C delta C1b domain mutant (L20G)More data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Displacement of 3[H]PDBu from Protein kinase C epsilon C1a domainMore data for this Ligand-Target Pair
TargetProtein kinase C delta type(Homo sapiens (Human))
Georgetown University Medical Center
Curated by ChEMBL
Georgetown University Medical Center
Curated by ChEMBL
Affinity DataKi: 12nMAssay Description:Inhibition of [3H]-PDBu binding to PKC delta mutant Leu 20-GlyMore data for this Ligand-Target Pair
Affinity DataKi: 14.2nMAssay Description:Displacement of [3H]PDBu from protein kinase C delta C1b domain mutant (Q27V)More data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Displacement of 3[H]PDBu from Protein kinase C gamma C1b domainMore data for this Ligand-Target Pair
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Bethesda
Curated by ChEMBL
National Cancer Institute-Bethesda
Curated by ChEMBL
Affinity DataKi: 17nMAssay Description:Displacement of 3[H]PDBu from Protein kinase C alpha C1a domainMore data for this Ligand-Target Pair
Affinity DataKi: 18.4nMAssay Description:Displacement of [3H]PDBu from protein kinase C delta C1b domain mutant (T8G)More data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:Ratio of Ki for mouse wild type C1b domain of PKCdelta to Ki for mouse PKCdelta C1b Q27E mutantMore data for this Ligand-Target Pair
TargetProtein kinase C delta type(Homo sapiens (Human))
Georgetown University Medical Center
Curated by ChEMBL
Georgetown University Medical Center
Curated by ChEMBL
Affinity DataKi: 22nMAssay Description:Inhibition of [3H]-PDBu binding to PKC delta mutant Gln 27-ValMore data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Displacement of [3H]PDBu from protein kinase C delta C1b domain mutant (W22G)More data for this Ligand-Target Pair
Affinity DataKi: 53nMAssay Description:Inhibition of [3H]- PDBu binding to peptide C, rat brain PKC gammaMore data for this Ligand-Target Pair
TargetProtein kinase C delta type(Homo sapiens (Human))
Georgetown University Medical Center
Curated by ChEMBL
Georgetown University Medical Center
Curated by ChEMBL
Affinity DataKi: 100nMAssay Description:Inhibition of [3H]-PDBu binding to PKC delta mutant Pro 11-GlyMore data for this Ligand-Target Pair
TargetProtein kinase C delta type(Homo sapiens (Human))
Georgetown University Medical Center
Curated by ChEMBL
Georgetown University Medical Center
Curated by ChEMBL
Affinity DataKi: 107nMAssay Description:Displacement of 3[H]PDBu from Protein kinase C alpha C1b domainMore data for this Ligand-Target Pair
Affinity DataKi: 210nMAssay Description:Displacement of [3H]-PDBu from protein kinase C delta C1b domain mutant (P11G)More data for this Ligand-Target Pair