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Found 14 of ic50 for monomerid = 50081194
TargetNeuromedin-K receptor(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50081194(CHEMBL3422009 | US10544150, Compound 156)
Affinity DataIC50:  20nMAssay Description:Antagonist activity at recombinant human NK3R expressed in CHO cells assessed as inhibition of NKB-induced Ca2+ signaling by aequorin Ca2+ biolumines...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50081194(CHEMBL3422009 | US10544150, Compound 156)
Affinity DataIC50:  20nMAssay Description:Antagonist activity against human recombinant NK3R expressed in CHO cells by aequorin functional assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50081194(CHEMBL3422009 | US10544150, Compound 156)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of human ERG expressed in HEK293 cells after 5 mins by patch-clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50081194(CHEMBL3422009 | US10544150, Compound 156)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50081194(CHEMBL3422009 | US10544150, Compound 156)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50081194(CHEMBL3422009 | US10544150, Compound 156)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of CYP2C9 (unknown origin) by luciferase reporter assay in presence of NADPH regeneration systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50081194(CHEMBL3422009 | US10544150, Compound 156)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50081194(CHEMBL3422009 | US10544150, Compound 156)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of CYP2C19 (unknown origin) by luciferase reporter assay in presence of NADPH regeneration systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50081194(CHEMBL3422009 | US10544150, Compound 156)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of CYP2D6 (unknown origin) by luciferase reporter assay in presence of NADPH regeneration systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50081194(CHEMBL3422009 | US10544150, Compound 156)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50081194(CHEMBL3422009 | US10544150, Compound 156)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50081194(CHEMBL3422009 | US10544150, Compound 156)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin) by luciferase reporter assay in presence of NADPH regeneration systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50081194(CHEMBL3422009 | US10544150, Compound 156)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin) by luciferase reporter assay in presence of NADPH regeneration systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50081194(CHEMBL3422009 | US10544150, Compound 156)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed