Compile Data Set for Download or QSAR
maximum 50k data
Found 11 of ic50 for monomerid = 50083230
TargetNociceptin receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50083230(1-((3R,4R)-1-Cyclooctylmethyl-3-hydroxymethyl-pipe...)
Affinity DataIC50:  1.5nMAssay Description:Antagonist activity on nociceptin-induced [35S]GTPgammaS binding to ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50083230(1-((3R,4R)-1-Cyclooctylmethyl-3-hydroxymethyl-pipe...)
Affinity DataIC50:  2.30nMAssay Description:Binding affinity of the compound in CHO cells stably expressing cloned human Opioid receptor like 1 by displacing radioligand [125I]-Tyr14-nociceptinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50083230(1-((3R,4R)-1-Cyclooctylmethyl-3-hydroxymethyl-pipe...)
Affinity DataIC50:  2.30nMAssay Description:Displacement of [125I]Tyr14-nociceptin from human cloned ORL1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50083230(1-((3R,4R)-1-Cyclooctylmethyl-3-hydroxymethyl-pipe...)
Affinity DataIC50:  2.40nMAssay Description:Displacement of [125I]Tyr-nociceptin from cloned human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50083230(1-((3R,4R)-1-Cyclooctylmethyl-3-hydroxymethyl-pipe...)
Affinity DataIC50:  5.60nMAssay Description:Inhibition of [125I]Tyr14-nociceptin binding to human Opioid receptor like 1 (opioid receptor like 1) in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50083230(1-((3R,4R)-1-Cyclooctylmethyl-3-hydroxymethyl-pipe...)
Affinity DataIC50:  1.40E+3nMAssay Description:Binding affinity of the compound in CHO cells stably expressing cloned human Opioid receptor kappa 1 by displacing radioligand [3H]-U-69,593More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50083230(1-((3R,4R)-1-Cyclooctylmethyl-3-hydroxymethyl-pipe...)
Affinity DataIC50:  1.60E+3nMAssay Description:Displacement of [3H]U-69593 from cloned human kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50083230(1-((3R,4R)-1-Cyclooctylmethyl-3-hydroxymethyl-pipe...)
Affinity DataIC50:  2.20E+3nMAssay Description:Binding affinity in CHO cells stably expressing cloned human Opioid receptor mu 1 by displacing diprenorphineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50083230(1-((3R,4R)-1-Cyclooctylmethyl-3-hydroxymethyl-pipe...)
Affinity DataIC50:  3.40E+3nMAssay Description:Displacement of [3H]diprenorphin from cloned human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50083230(1-((3R,4R)-1-Cyclooctylmethyl-3-hydroxymethyl-pipe...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity of the compound in CHO cells stably expressing cloned human Opioid receptor delta 1 by displacing radioligand [3H][D-Ala2,D-Leu5]enk...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50083230(1-((3R,4R)-1-Cyclooctylmethyl-3-hydroxymethyl-pipe...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]naltrindole from cloned human delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed