TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataKi: 190nMAssay Description:Binding affinity at hERG expressed in HEK293 cells by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKi: 280nMAssay Description:Inhibition of recombinant CYP3A4 (unknown origin) expressed in baculosomes in presence of 1 mM NADPHMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataKi: 353nMAssay Description:Displacement of [3H]dofetilide from hERG expressed in HEK293 cells by SPAMore data for this Ligand-Target Pair
Affinity DataKi: 2.30E+3nMAssay Description:Time dependent inhibition of CYP3A4More data for this Ligand-Target Pair