Compile Data Set for Download or QSAR
maximum 50k data
Found 15 of ic50 for monomerid = 50124010
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50124010(2-(4-Fluoro-benzenesulfonylamino)-N-(1-formyl-3-me...)
Affinity DataIC50:  7.5nMAssay Description:In vitro inhibition of porcine mu-calpain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50124010(2-(4-Fluoro-benzenesulfonylamino)-N-(1-formyl-3-me...)
Affinity DataIC50:  78nMAssay Description:Inhibitory activity against Cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Rattus norvegicus)
University Of Canterbury

Curated by ChEMBL
LigandPNGBDBM50124010(2-(4-Fluoro-benzenesulfonylamino)-N-(1-formyl-3-me...)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of rat CAPN1 using BODIPY-labeled casein substrate by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50124010(2-(4-Fluoro-benzenesulfonylamino)-N-(1-formyl-3-me...)
Affinity DataIC50: >6.00E+4nMAssay Description:Inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50124010(2-(4-Fluoro-benzenesulfonylamino)-N-(1-formyl-3-me...)
Affinity DataIC50:  8.10E+4nMAssay Description:Inhibition of Cytochrome P450 3A4 as BFC substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50124010(2-(4-Fluoro-benzenesulfonylamino)-N-(1-formyl-3-me...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50124010(2-(4-Fluoro-benzenesulfonylamino)-N-(1-formyl-3-me...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against coagulation factor VIIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50124010(2-(4-Fluoro-benzenesulfonylamino)-N-(1-formyl-3-me...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against interleukin 1beta converting enzyme (IL-1 beta converting enzyme)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50124010(2-(4-Fluoro-benzenesulfonylamino)-N-(1-formyl-3-me...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50124010(2-(4-Fluoro-benzenesulfonylamino)-N-(1-formyl-3-me...)
Affinity DataIC50:  1.77E+5nMAssay Description:Inhibition of Cytochrome P450 2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50124010(2-(4-Fluoro-benzenesulfonylamino)-N-(1-formyl-3-me...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibitory activity against ChymotrypsinogenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50124010(2-(4-Fluoro-benzenesulfonylamino)-N-(1-formyl-3-me...)
Affinity DataIC50:  2.91E+5nMAssay Description:Inhibition of Cytochrome P450 2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50124010(2-(4-Fluoro-benzenesulfonylamino)-N-(1-formyl-3-me...)
Affinity DataIC50:  4.92E+5nMAssay Description:Inhibition of Cytochrome P450 2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50124010(2-(4-Fluoro-benzenesulfonylamino)-N-(1-formyl-3-me...)
Affinity DataIC50:  5.31E+5nMAssay Description:Inhibition of Cytochrome P450 3A4 as BQ substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50124010(2-(4-Fluoro-benzenesulfonylamino)-N-(1-formyl-3-me...)
Affinity DataIC50:  1.00E+6nMAssay Description:Inhibition of Cytochrome P450 1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed