TargetSolute carrier organic anion transporter family member 1B3(Homo sapiens (Human))
Universit£Tsmedizin G£Ttingen
Curated by ChEMBL
Universit£Tsmedizin G£Ttingen
Curated by ChEMBL
Affinity DataKi: 1.35E+4nMAssay Description:Inhibition of human OATP1B3-mediated [3H]CCK-8 after 5 mins by Dixon plot methodMore data for this Ligand-Target Pair
Affinity DataKi: 1.31E+5nM IC50: 2.26E+5nMpH: 10.5Assay Description:Paraoxonase enzyme activity was determined at 25 °C with paraoxon (1 mM) in 50 mM glycine-NaOH (pH 10.5) containing 1 mM CaCl2. The enzyme assay was ...More data for this Ligand-Target Pair
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
The University Of Kansas
Curated by ChEMBL
The University Of Kansas
Curated by ChEMBL
Affinity DataKi: 2.76E+5nMAssay Description:TP_TRANSPORTER: inhibition of Taxol transepithelial transport (basal to apical) in Caco-2 cellsMore data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 2(Homo sapiens (Human))
The University Of Kansas
Curated by ChEMBL
The University Of Kansas
Curated by ChEMBL
Affinity DataKi: 7.56E+5nMAssay Description:TP_TRANSPORTER: inhibition of Vinblastine transepithelial transport (basal to apical) in MRP2-expressing MDCK cellsMore data for this Ligand-Target Pair
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
The University Of Kansas
Curated by ChEMBL
The University Of Kansas
Curated by ChEMBL
Affinity DataKi: 7.68E+5nMAssay Description:TP_TRANSPORTER: inhibition of Digoxin transepithelial transport (basal to apical) in MDR1-expressing MDCK cellsMore data for this Ligand-Target Pair