Affinity DataIC50: 54nMAssay Description:Displacement of human recombinant [125I]IL8 from CXCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 490nMAssay Description:Antagonist activity at CXCR2 receptor expressed in CHOK1 cells assessed as human IL8-induced calcium mobilization by FLIPRMore data for this Ligand-Target Pair
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of adrenergic alpha-1A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: >3.20E+3nMAssay Description:Inhibition of histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: >3.20E+3nMAssay Description:Inhibition of dopamine D2 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: >3.20E+3nMAssay Description:Inhibition of 5HT1A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: >3.20E+3nMAssay Description:Inhibition of 5HT1D receptorMore data for this Ligand-Target Pair
Affinity DataIC50: >3.20E+3nMAssay Description:Inhibition of 5HT1B receptorMore data for this Ligand-Target Pair
Affinity DataIC50: >3.20E+3nMAssay Description:Inhibition of dopamine D3 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 7.60E+3nMAssay Description:Displacement of human recombinant [125I]IL8 from CXCR1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: >7.90E+3nMAssay Description:Inhibition of 5HT6 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of PAI1More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of histamine H1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of 5HT2C receptorMore data for this Ligand-Target Pair
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of adrenergic beta2 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of P38alphaMore data for this Ligand-Target Pair
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of adrenergic A1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of P2Y1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of adrenergic beta-1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of 5HT4A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of adenosine A2a receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of 5HT7 receptorMore data for this Ligand-Target Pair