Compile Data Set for Download or QSAR
maximum 50k data
Found 22 of ic50 for monomerid = 50255753
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50255753(CHEMBL481611 | MK-0822 | Odanacatib)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of humanized rabbit cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50255753(CHEMBL481611 | MK-0822 | Odanacatib)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of humanized rabbit cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50255753(CHEMBL481611 | MK-0822 | Odanacatib)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of human cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50255753(CHEMBL481611 | MK-0822 | Odanacatib)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of humanized rabbit cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50255753(CHEMBL481611 | MK-0822 | Odanacatib)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of humanized rabbit cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50255753(CHEMBL481611 | MK-0822 | Odanacatib)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Oryctolagus cuniculus (rabbit))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50255753(CHEMBL481611 | MK-0822 | Odanacatib)
Affinity DataIC50:  1nMAssay Description:Inhibition of rabbit cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50255753(CHEMBL481611 | MK-0822 | Odanacatib)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of Cathepsin K (unknown origin) assessed as inhibition of AFC release using sequence LR labelled with AFC as substrate by fluorescence bas...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50255753(CHEMBL481611 | MK-0822 | Odanacatib)
Affinity DataIC50: >10nMAssay Description:Inhibition of cathepsin CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin Z(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50255753(CHEMBL481611 | MK-0822 | Odanacatib)
Affinity DataIC50: >10nMAssay Description:Inhibition of cathepsin ZMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPro-cathepsin H(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50255753(CHEMBL481611 | MK-0822 | Odanacatib)
Affinity DataIC50: >10nMAssay Description:Inhibition of cathepsin HMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50255753(CHEMBL481611 | MK-0822 | Odanacatib)
Affinity DataIC50:  45nMAssay Description:Inhibition of cathepsin S in human ramos cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50255753(CHEMBL481611 | MK-0822 | Odanacatib)
Affinity DataIC50:  60nMAssay Description:Inhibition of cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50255753(CHEMBL481611 | MK-0822 | Odanacatib)
Affinity DataIC50:  183nMAssay Description:Inhibition of human recombinant CatS assessed as suppression of enzyme-mediated Z-Val-Val-Arg-AMC cleavage by QFRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50255753(CHEMBL481611 | MK-0822 | Odanacatib)
Affinity DataIC50: <500nMAssay Description:Inhibition of Cathepsin S (unknown origin) assessed as inhibition of AFC release using sequence VVR labelled with AFC as substrate by fluorescence ba...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCathepsin L2(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50255753(CHEMBL481611 | MK-0822 | Odanacatib)
Affinity DataIC50:  762nMAssay Description:Inhibition of cathepsin VMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin F(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50255753(CHEMBL481611 | MK-0822 | Odanacatib)
Affinity DataIC50:  795nMAssay Description:Inhibition of cathepsin FMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50255753(CHEMBL481611 | MK-0822 | Odanacatib)
Affinity DataIC50:  1.03E+3nMAssay Description:Inhibition of cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50255753(CHEMBL481611 | MK-0822 | Odanacatib)
Affinity DataIC50:  1.05E+3nMAssay Description:Inhibition of cathepsin B in human HepG2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50255753(CHEMBL481611 | MK-0822 | Odanacatib)
Affinity DataIC50: <2.00E+3nMAssay Description:Inhibition of Cathepsin B (unknown origin) assessed as inhibition of AFC release using sequence RR labelled with AFC as substrate by fluorescence bas...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProcathepsin L(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50255753(CHEMBL481611 | MK-0822 | Odanacatib)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50255753(CHEMBL481611 | MK-0822 | Odanacatib)
Affinity DataIC50:  4.84E+3nMAssay Description:Inhibition of cathepsin L in human HepG2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed