Found 14 of ec50 for monomerid = 50283472 TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Vanderbilt University
Curated by ChEMBL
Vanderbilt University
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of rat mGlu5 receptor expressed in HEK cells assessed as increase in glutamate-induced calcium flux incubated for 142 ...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 8(Rattus norvegicus (Rat))
Vanderbilt University
Curated by ChEMBL
Vanderbilt University
Curated by ChEMBL
Affinity DataEC50: 2.63E+3nMAssay Description:Positive allosteric modulation of rat mGlu8 receptor expressed in HEK cells co-expressing Galphai5 assessed as increase in glutamate-induced calcium ...More data for this Ligand-Target Pair
Affinity DataEC50: <1.00E+4nMAssay Description:Positive allosteric modulation of human mGlu4 receptor expressed in CHO cells co-expressing Gqi5 assessed as increase in glutamate-induced calcium mo...More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human mGlu4 receptor expressed in CHO cells co-expressing Gqi5 assessed as increase in glutamate-induced calcium mo...More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of rat mGlu2 receptor expressed in HEK cells assessed as increase in glutamate-induced calcium flux incubated for 142 ...More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of rat mGlu1 receptor expressed in HEK cells assessed as increase in glutamate-induced calcium flux incubated for 142 ...More data for this Ligand-Target Pair
Affinity DataEC50: 2.60E+3nMAssay Description:Positive allosteric modulation of mGluR8 (unknown origin)More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Vanderbilt University
Curated by ChEMBL
Vanderbilt University
Curated by ChEMBL
Affinity DataEC50: 646nMAssay Description:Positive allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galphai5 assessed as increase in glutamate-induced calcium ...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Rattus norvegicus (Rat))
Vanderbilt University
Curated by ChEMBL
Vanderbilt University
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of rat mGlu3 receptor expressed in HEK cells assessed as increase in glutamate-induced calcium flux incubated for 142 ...More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human mGlu6 receptor expressed in HEK cells assessed as increase in glutamate-induced calcium flux incubated for 14...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Vanderbilt University
Curated by ChEMBL
Vanderbilt University
Curated by ChEMBL
Affinity DataEC50: 650nMAssay Description:Positive allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galphai5 assessed as increase in glutamate-induced calcium ...More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of mGluR4 (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 649nMAssay Description:Positive allosteric modulation of mGluR7 (unknown origin)More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 8(Rattus norvegicus (Rat))
Vanderbilt University
Curated by ChEMBL
Vanderbilt University
Curated by ChEMBL
Affinity DataEC50: 2.60E+3nMAssay Description:Positive allosteric modulation of rat mGlu8 receptor expressed in HEK cells co-expressing Galphai5 assessed as increase in glutamate-induced calcium ...More data for this Ligand-Target Pair
