Compile Data Set for Download or QSAR
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Found 95 of ic50 for monomerid = 50335638
TargetCasein kinase II subunit alpha'/beta(Homo sapiens (Human))
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of human recombinant CK2alpha/CK2beta using RRRDDDSDDD peptide as substrate by radiometric assayMore data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha(Homo sapiens (Human))
University Of Tartu

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50:  0.5nMAssay Description:Displacement of 5-TAMRA-labeled ARC-1530 from CK2alpha (unknown origin) (1 to 335 residues) after 15 to 60 mins by luminescence assayMore data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK2(Homo sapiens (Human))
Southeast University

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50:  0.550nMAssay Description:Inhibition of human CLK2 incubated for 2 hrsMore data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha(Homo sapiens (Human))
University Of Tartu

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50:  1nMAssay Description:Inhibition of human recombinant CK2alpha at enzyme-substrate complex by radiometric assayMore data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha(Homo sapiens (Human))
University Of Tartu

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50:  1nMAssay Description:Inhibition of human recombinant CK2alpha by radiometric assayMore data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha(Homo sapiens (Human))
University Of Tartu

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50:  1nMAssay Description:Inhibition of human recombinant CK2alphaMore data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha'(Homo sapiens (Human))
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50:  1nMAssay Description:Inhibition of recombinant human CK2alpha' in presence of ATP at Km concentration by radiometric filter-binding assayMore data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha(Homo sapiens (Human))
University Of Tartu

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50:  1nMAssay Description:Inhibition of recombinant human CK2alpha in presence of ATP at Km concentration by radiometric filter-binding assayMore data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha(Homo sapiens (Human))
University Of Tartu

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50:  1nMAssay Description:Inhibition of recombinant human CK2alpha (1 to 336 residues) expressed in Escherichia coli BL21 (DE3) using RRADDSDDDD as substrate incubated for 10 ...More data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha 3(Homo sapiens)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of human CK2 incubated for 2 hrsMore data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha 3(Homo sapiens)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of human recombinant CK2 using RRRDDDSDDD peptide as substrate preincubated for 30 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of recombinant human DYRK1A expressed in Escherichia coli using DYRKtide peptide as substrate incubated for 110 mins in presence of ATP by...More data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha(Homo sapiens (Human))
University Of Tartu

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50:  2nMpH: 7.2Assay Description:Test compounds in aqueous solution were added at a volume of 10 microliters, to a reaction mixture comprising 10 microliters Assay Dilution Buffer (A...More data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha(Homo sapiens (Human))
University Of Tartu

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50:  2nMAssay Description:Test compounds in aqueous solution were added at a volume of 10 microliters, to a reaction mixture comprising 10 microliters Assay Dilution Buffer (A...More data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))TBA
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of recombinant human CLK4 expressed in Sf9 insect cells incubated for 60 mins in presence of ATP and [gamma33-P] ATP by radiometric scinti...More data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK2(Homo sapiens (Human))
Southeast University

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of recombinant human CLK2 expressed in Sf9 insect cells incubated for 60 mins in presence of ATP and [gamma33-P] ATP by radiometric scinti...More data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha(Homo sapiens (Human))
University Of Tartu

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50: <3nMAssay Description:Inhibition of recombinant human full length N-terminal His6-tagged CK2alpha expressed in Sf21 insect cells using CK2tide as substrate treated for 20 ...More data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha 3(Homo sapiens)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50:  3nMAssay Description:Inhibition of CK2 (unknown origin)More data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK2(Homo sapiens (Human))
Southeast University

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of CLK2 (unknown origin)More data for this Ligand-Target Pair
TargetCasein kinase I isoform alpha/delta/epsilon/gamma-1/gamma-2(Homo sapiens (Human))
Sichuan University-Oxford University Huaxi Gastrointestinal Cancer Centre

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50:  4nMAssay Description:Inhibition of CK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK2(Homo sapiens (Human))
Southeast University

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50:  4nMAssay Description:Inhibition of recombinant human CLK2 in presence of ATP by radiometric filter-binding assayMore data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK2(Homo sapiens (Human))
Southeast University

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50:  4nMAssay Description:Inhibition of N-terminal GST-tagged human CLK2 (138 to end residues) using SR-rich substrate and [gamma-33P]ATP incubated for 40 mins by scintillatio...More data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK2(Homo sapiens (Human))
Southeast University

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50:  4nMAssay Description:Inhibition of recombinant human CLK2 in presence of ATP by radiometric filter-binding assayMore data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK2(Homo sapiens (Human))
Southeast University

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50:  4nMAssay Description:Inhibition of N-terminal GST-tagged human CLK2 (138 to end residues) using SR-rich substrate and [gamma-33P]ATP incubated for 40 mins by scintillatio...More data for this Ligand-Target Pair
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50:  4.60nMAssay Description:Inhibition of recombinant human DYRK1B expressed in Sf9 insect cells using DYRKtide peptide as substrate incubated for 110 mins in presence of ATP by...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCasein kinase II subunit alpha(Homo sapiens (Human))
University Of Tartu

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50:  6nMAssay Description:Displacement of fluorescent tracer from full-length human C-terminal NanoLuc-tagged CK2alpha expressed in HEK293T permeabilized cells measured after ...More data for this Ligand-Target Pair
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50:  6.20nMAssay Description:Inhibition of recombinant human DYRK1B expressed in Sf9 insect cells incubated for 60 mins in presence of ATP and [gamma33-P] ATP by radiometric scin...More data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50:  6.40nMAssay Description:Inhibition of recombinant human DYRK1B by radiometric filter-binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50:  6.40nMAssay Description:Inhibition of human recombinant DyrK1b by fluorescence-based immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50:  6.40nMAssay Description:Inhibition of human recombinant DyrK1b by fluorescence-based immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50:  6.40nMAssay Description:Inhibition of recombinant human DYRK1B in presence of ATP by radiometric filter-binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50:  6.40nMAssay Description:Inhibition of recombinant human DYRK1B in presence of ATP by radiometric filter-binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50:  6.80nMAssay Description:Inhibition of recombinant human DYRK1A by radiometric filter-binding assayMore data for this Ligand-Target Pair
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50:  6.80nMAssay Description:Inhibition of recombinant human DYRK1A in presence of ATP by radiometric filter-binding assayMore data for this Ligand-Target Pair
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50:  6.80nMAssay Description:Inhibition of human recombinant DyrK1a by fluorescence-based immunoassayMore data for this Ligand-Target Pair
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50:  6.80nMAssay Description:Inhibition of human recombinant DyrK1a by fluorescence-based immunoassayMore data for this Ligand-Target Pair
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50:  6.80nMAssay Description:Inhibition of recombinant human DYRK1A in presence of ATP by radiometric filter-binding assayMore data for this Ligand-Target Pair
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50:  7nMAssay Description:Inhibition of DYRK1A (unknown origin) measured after 6 hrs in presence of ATP by Z'-LYTE assayMore data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK2(Homo sapiens (Human))
Southeast University

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50:  7nMAssay Description:Inhibition of human CLK2 Long (130 to 496 residues) expressed in Escherichia coli BL21 (DE3) Turner using GSK3 as substrate incubated for 60 mins in ...More data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))TBA
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50:  8.60nMAssay Description:Inhibition of recombinant human CLK1 expressed in Sf9 insect cells incubated for 60 mins in presence of ATP and [gamma33-P] ATP by radiometric scinti...More data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))TBA
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50:  9.10nMAssay Description:Inhibition of recombinant human CLK1 expressed in Sf9 insect cells using myelin basic protein as substrate incubated for 110 mins in presence of ATP ...More data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha'(Homo sapiens (Human))
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50:  11nMAssay Description:Inhibition of GST-tagged human CK2alpha' (1 to 350 residues) using CK2tide as substrate incubated for 1 hr by off-chip mobility shift assayMore data for this Ligand-Target Pair
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50:  11nMAssay Description:Inhibition of recombinant human DYRK1A expressed in Sf9 insect cells incubated for 60 mins in presence of ATP and [gamma33-P] ATP by radiometric scin...More data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))TBA
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50:  11nMAssay Description:Inhibition of human CLK4 (146 to 480 residues) expressed in Escherichia coli BL21 (DE3) Turner using MBP as substrate incubated for 60 mins in presen...More data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))TBA
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50:  12nMAssay Description:Inhibition of human CLK1 Long (148 to 484 residues) expressed in Escherichia coli BL21 (DE3) Turner incubated for 60 mins in presence of [gamma-32P]A...More data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha(Homo sapiens (Human))
University Of Tartu

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50:  14nMAssay Description:Inhibition of recombinant human CK2alpha using RRRDDDSDDD substrate and [gamma-33P]ATP by scintillation counting methodMore data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha(Homo sapiens (Human))
University Of Tartu

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50:  14nMAssay Description:Inhibition of recombinant human CK2alpha using RRRDDDSDDD substrate and [gamma-33P]ATP by scintillation counting methodMore data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha(Homo sapiens (Human))
University Of Tartu

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50:  15nMAssay Description:Inhibition of CK2alpha (unknown origin) (2 to 329 residues) expressed in Escherichia coli BL21 (DE3) using RRRADDSDDDD substrate incubated for 40 min...More data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha(Homo sapiens (Human))
University Of Tartu

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50:  15nMAssay Description:Inhibition of recombinant human GST-tagged CK2alpha in presence of ATP by radiometric kinase assayMore data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha(Homo sapiens (Human))
University Of Tartu

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50:  15nMAssay Description:Inhibition of recombinant human GST-tagged CK2alpha in presence of ATP by radiometric kinase assayMore data for this Ligand-Target Pair
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