Compile Data Set for Download or QSAR
maximum 50k data
Found 8 of ic50 for monomerid = 50383522
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50383522(CHEMBL2032049)
Affinity DataIC50:  0.600nMAssay Description:Displacement of [125I]-MCH from MCHR1 after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Mus musculus)
Amgen

Curated by ChEMBL
LigandPNGBDBM50383522(CHEMBL2032049)
Affinity DataIC50:  0.600nMAssay Description:Antagonist activity at mouse MCHR1 assessed inhibition of MCH-mediated intracellular Ca2+ calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50383522(CHEMBL2032049)
Affinity DataIC50:  0.800nMAssay Description:Antagonist activity at rat MCHR1 assessed inhibition of MCH-mediated intracellular Ca2+ calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Macaca mulatta)
Amgen

Curated by ChEMBL
LigandPNGBDBM50383522(CHEMBL2032049)
Affinity DataIC50:  0.800nMAssay Description:Antagonist activity at rhesus monkey MCHR1 assessed inhibition of MCH-mediated intracellular Ca2+ calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50383522(CHEMBL2032049)
Affinity DataIC50:  1.20nMAssay Description:Antagonist activity at human MCHR1 assessed inhibition of MCH-mediated intracellular Ca2+ calcium mobilization by aequorin assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50383522(CHEMBL2032049)
Affinity DataIC50:  1.14E+3nMAssay Description:Antagonist activity at serotonin 5HT2C receptor assessed as blockage of intracellular calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50383522(CHEMBL2032049)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of human Erg expressed in HEK293 cells assessed as rubidium efflux after 4 hrs by atomic absorbance spectrometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50383522(CHEMBL2032049)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at human MCHR2 assessed inhibition of MCH-mediated intracellular Ca2+ calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed