BindingDB PrimarySearch

Found 18 of ic50 for monomerid = 50425808

Tyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL

BDBM50425808(CHEMBL2316906)

IC50: 1.30E+3nMAssay Description:Inhibition of LYP (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair

PDB Reactome pathway
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CHEMBL PC cid PC sid Similars

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Tyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL

BDBM50425808(CHEMBL2316906)

IC50: 1.30E+3nMAssay Description:Inhibition of N-terminal 6xHis-tagged LYP catalytic domain (1 to 303) (unknown origin) expressed in Escherichia coli BL21(DE3) using pNPP as substrat...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Tyrosine-protein phosphatase non-receptor type 13(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL

BDBM50425808(CHEMBL2316906)

IC50: 1.90E+3nMAssay Description:Inhibition of FAP1 (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Tyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL

BDBM50425808(CHEMBL2316906)

IC50: 2.20E+3nMAssay Description:Inhibition of SHP2 (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Tyrosine-protein phosphatase non-receptor type 9(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL

BDBM50425808(CHEMBL2316906)

IC50: 2.30E+3nMAssay Description:Inhibition of PTPMEG2 (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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Tyrosine-protein phosphatase non-receptor type 6(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL

BDBM50425808(CHEMBL2316906)

IC50: 2.30E+3nMAssay Description:Inhibition of SHP1 (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Dual specificity protein phosphatase 22(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL

BDBM50425808(CHEMBL2316906)

IC50: 2.90E+3nMAssay Description:Inhibition of VHX (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair

PDB MMDB KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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Low molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL

BDBM50425808(CHEMBL2316906)

IC50: 2.90E+3nMAssay Description:Inhibition of LMWPTP (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
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CHEMBL PC cid PC sid Similars

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Tyrosine-protein phosphatase non-receptor type 7(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL

BDBM50425808(CHEMBL2316906)

IC50: 3.30E+3nMAssay Description:Inhibition of HEPTP (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Receptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL

BDBM50425808(CHEMBL2316906)

IC50: 4.10E+3nMAssay Description:Inhibition of CD45 (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

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Tyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL

BDBM50425808(CHEMBL2316906)

IC50: 4.50E+3nMAssay Description:Inhibition of PTP1B (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Receptor-type tyrosine-protein phosphatase gamma(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL

BDBM50425808(CHEMBL2316906)

IC50: 5.00E+3nMAssay Description:Inhibition of PTPgamma (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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Dual specificity protein phosphatase 3(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL

BDBM50425808(CHEMBL2316906)

IC50: 5.30E+3nMAssay Description:Inhibition of VHR (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Tyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL

BDBM50425808(CHEMBL2316906)

IC50: 6.10E+3nMAssay Description:Inhibition of TCPTP (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Receptor-type tyrosine-protein phosphatase alpha(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL

BDBM50425808(CHEMBL2316906)

IC50: >1.00E+4nMAssay Description:Inhibition of PTPalpha (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Receptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL

BDBM50425808(CHEMBL2316906)

IC50: >1.00E+4nMAssay Description:Inhibition of LAR (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Dual specificity protein phosphatase CDC14A(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL

BDBM50425808(CHEMBL2316906)

IC50: 2.10E+4nMAssay Description:Inhibition of CDC14A (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair

Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Laforin(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL

BDBM50425808(CHEMBL2316906)

IC50: >3.00E+4nMAssay Description:Inhibition of Laforin (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Filter my 18 hits

Targets 17▿
- Tyrosine-protein phosphatase non-receptor type 22 2
- Dual specificity protein phosphatase 22 1
- Low molecular weight phosphotyrosine protein phosphatase 1
- Laforin 1
- Tyrosine-protein phosphatase non-receptor type 13 1
- Tyrosine-protein phosphatase non-receptor type 11 1
- Receptor-type tyrosine-protein phosphatase alpha 1
- Tyrosine-protein phosphatase non-receptor type 7 1
- Receptor-type tyrosine-protein phosphatase C 1
- Dual specificity protein phosphatase 3 1
- Tyrosine-protein phosphatase non-receptor type 6 1
- Receptor-type tyrosine-protein phosphatase F 1
- Receptor-type tyrosine-protein phosphatase gamma 1
- Tyrosine-protein phosphatase non-receptor type 1 1
- Tyrosine-protein phosphatase non-receptor type 2 1
- Dual specificity protein phosphatase CDC14A 1
- Tyrosine-protein phosphatase non-receptor type 9 1
Publications 2▿
- J Med Chem 56: 832-42 (2013) 17
- J Med Chem 56: 4990-5008 (2013) 1
Institutions 1▿
- Indiana University School Of Medicine 18
Affinity: 1.3E+3 to 3.0E+4 nM▿
- IC50 18
- Affinity ≤ nM
Xtal structures: 0
Docked structures: 0
Catalog Cmpds: 0