Compile Data Set for Download or QSAR
Report error Found 48 of ki for UniProtKB: P05177
TargetCytochrome P450 1A2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50418082BDBM50418082(CHEMBL1743360)
Affinity DataKi:  13nMAssay Description:Mechanism based inhibition of human cytochrome P450 1A2 measured by 7-methoxyresorufin O-demethylation (MROD)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50432672BDBM50432672(CHEMBL2347912)
Affinity DataKi:  14nMAssay Description:Inhibition of human microsomal CYP1A2-dependent methoxyresorufin-O-demethylase activity by spectrofluorimetric analysis in presence of NADPH regenera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2016
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50014323BDBM50014323(CHEMBL283196 | alpha-naphthoflavone | 2-PHENYL-4H-...)
Affinity DataKi:  20nMAssay Description:Inhibition of human microsomal CYP1A2-dependent methoxyresorufin-O-demethylase activity by spectrofluorimetric analysis in presence of NADPH regenera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCytochrome P450 1A2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50113259BDBM50113259(CHEMBL3601433)
Affinity DataKi:  30nMAssay Description:Inhibition of human microsomal CYP1A2-dependent methoxyresorufin-O-demethylase activity by spectrofluorimetric analysis in presence of NADPH regenera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2016
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50113260BDBM50113260(CHEMBL3601434)
Affinity DataKi:  44nMAssay Description:Inhibition of human microsomal CYP1A2-dependent methoxyresorufin-O-demethylase activity by spectrofluorimetric analysis in presence of NADPH regenera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2016
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50081468BDBM50081468(CHEMBL3422028)
Affinity DataKi:  56nMAssay Description:Inhibition of human recombinant CYP1A2 assessed as metabolism of 3-cyano-7-ethoxycoumarin after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2016
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50432677BDBM50432677(CHEMBL2347756)
Affinity DataKi:  58nMAssay Description:Inhibition of human microsomal CYP1A2-dependent methoxyresorufin-O-demethylase activity by spectrofluorimetric analysis in presence of NADPH regenera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2016
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50432670BDBM50432670(CHEMBL2347914)
Affinity DataKi:  71nMAssay Description:Irreversible inhibition of CYP1A2 (unknown origin)-mediated demethylation of resorufin methyl ether after 5 mins by spectrofluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50113261BDBM50113261(CHEMBL3601435)
Affinity DataKi:  76nMAssay Description:Inhibition of human microsomal CYP1A2-dependent methoxyresorufin-O-demethylase activity by spectrofluorimetric analysis in presence of NADPH regenera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2016
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50435005BDBM50435005(CHEMBL2386285)
Affinity DataKi:  76nMAssay Description:Inhibition of human recombinant CYP1A2 assessed as metabolism of 3-cyano-7-ethoxycoumarin after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2016
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50061117BDBM50061117(6,6,9-Trimethyl-3-pentyl-6H-benzo[c]chromen-1-ol(C...)
Affinity DataKi:  79nMAssay Description:Competitive inhibition of human liver microsomes CYP1A2 expressed in supersomes coexpressing NADPH-CYP reductase using 7-Ethoxyresorufin as substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2019
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50113262BDBM50113262(CHEMBL3601436)
Affinity DataKi:  90nMAssay Description:Inhibition of human microsomal CYP1A2-dependent methoxyresorufin-O-demethylase activity by spectrofluorimetric analysis in presence of NADPH regenera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2016
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50113260BDBM50113260(CHEMBL3601434)
Affinity DataKi:  120nMAssay Description:Time-dependent inhibition of human microsomal CYP1A2-dependent methoxyresorufin-O-demethylase activity by spectrofluorimetric analysis in presence of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2016
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50113268BDBM50113268(CHEMBL3601440)
Affinity DataKi:  390nMAssay Description:Inhibition of human microsomal CYP1A2-dependent methoxyresorufin-O-demethylase activity by spectrofluorimetric analysis in presence of NADPH regenera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2016
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50113259BDBM50113259(CHEMBL3601433)
Affinity DataKi:  440nMAssay Description:Time-dependent inhibition of human microsomal CYP1A2-dependent methoxyresorufin-O-demethylase activity by spectrofluorimetric analysis in presence of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2016
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50084137BDBM50084137(2-Methyl-6-phenylethynyl-pyridine | CHEMBL66654 | ...)
Affinity DataKi:  500nMAssay Description:Competitive inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate after 20 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 7461BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | cid_5281...)
Affinity DataKi:  500nMAssay Description:Inhibition of recombinant human CYP1A2 expressed in Escherichia coli DH5alpha coexpressing human NADPH-cytochrome P450 reductase in using 7-ethoxyres...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2019
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50084137BDBM50084137(2-Methyl-6-phenylethynyl-pyridine | CHEMBL66654 | ...)
Affinity DataKi:  500nMAssay Description:Competitive inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate after 20 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122758BDBM50122758(3-(2-(2-methylthiazol-4-yl)ethynyl)pyridine | 3-[(...)
Affinity DataKi:  500nMAssay Description:Competitive inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate after 20 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122758BDBM50122758(3-(2-(2-methylthiazol-4-yl)ethynyl)pyridine | 3-[(...)
Affinity DataKi:  500nMAssay Description:Competitive inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate after 20 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50121070BDBM50121070(CHEMBL3622017)
Affinity DataKi:  770nMAssay Description:Inhibition of CYP1A2 in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2016
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50593320BDBM50593320(IFIDANCITINIB | Ifidancitinib | Ati-502 | A-301 | ...)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetCytochrome P450 1A2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50113272BDBM50113272(CHEBI:82453 | CHEMBL50703)
Affinity DataKi:  1.15E+3nMAssay Description:Inhibition of human microsomal CYP1A2-dependent methoxyresorufin-O-demethylase activity by spectrofluorimetric analysis in presence of NADPH regenera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2016
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50113265BDBM50113265(CHEMBL3601437)
Affinity DataKi:  1.29E+3nMAssay Description:Inhibition of human microsomal CYP1A2-dependent methoxyresorufin-O-demethylase activity by spectrofluorimetric analysis in presence of NADPH regenera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2016
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50113273BDBM50113273(CHEMBL3601509)
Affinity DataKi:  1.35E+3nMAssay Description:Inhibition of human microsomal CYP1A2-dependent methoxyresorufin-O-demethylase activity by spectrofluorimetric analysis in presence of NADPH regenera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2016
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50113267BDBM50113267(CHEMBL3601439)
Affinity DataKi:  1.51E+3nMAssay Description:Inhibition of human microsomal CYP1A2-dependent methoxyresorufin-O-demethylase activity by spectrofluorimetric analysis in presence of NADPH regenera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2016
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50113266BDBM50113266(CHEMBL3601438)
Affinity DataKi:  1.72E+3nMAssay Description:Inhibition of human microsomal CYP1A2-dependent methoxyresorufin-O-demethylase activity by spectrofluorimetric analysis in presence of NADPH regenera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2016
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 8961BDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataKi:  1.94E+3nMAssay Description:Mechanism based inhibition of human cytochrome P450 1A2 measured by 7-ethoxyresorufin O-deethylation (EROD)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50417192BDBM50417192(CHEMBL1271476)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50318484BDBM50318484(CHEMBL190461 | 2-((1R,6R)-6-Isopropenyl-3-methyl-c...)
Affinity DataKi:  2.69E+3nMAssay Description:Competitive inhibition of human recombinant CYP1A2 using 7-Ethoxyresorufin as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50236897BDBM50236897(furafylline | 3-(furan-2-ylmethyl)-1,8-dimethyl-1H...)
Affinity DataKi:  3.00E+3nMAssay Description:Mechanism based inhibition of human cytochrome P450 1A2 measured by 7-ethoxyresorufin O-deethylation (EROD)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50113275BDBM50113275(CHEMBL3601511)
Affinity DataKi:  3.55E+3nMAssay Description:Inhibition of human microsomal CYP1A2-dependent methoxyresorufin-O-demethylase activity by spectrofluorimetric analysis in presence of NADPH regenera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2016
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50113271BDBM50113271(CHEMBL3601508)
Affinity DataKi:  3.70E+3nMAssay Description:Inhibition of human microsomal CYP1A2-dependent methoxyresorufin-O-demethylase activity by spectrofluorimetric analysis in presence of NADPH regenera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2016
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50113269BDBM50113269(CHEMBL3601441)
Affinity DataKi:  5.02E+3nMAssay Description:Inhibition of human microsomal CYP1A2-dependent methoxyresorufin-O-demethylase activity by spectrofluorimetric analysis in presence of NADPH regenera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2016
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50593319BDBM50593319(CHEMBL5188333)
Affinity DataKi:  6.00E+3nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetCytochrome P450 1A2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50418081BDBM50418081(OLTIPRAZ)
Affinity DataKi:  9.00E+3nMAssay Description:Mechanism based inhibition of human cytochrome P450 1A2 measured by 7-ethoxyresorufin O-deethylation (EROD)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 9019BDBM9019(CHEMBL45 | N-[2-(5-methoxy-1H-indol-3-yl)ethyl]ace...)
Affinity DataKi:  1.20E+4nMAssay Description:Mixed type inhibition of human hepatic microsomes CYP1A2 expressed in supersomes coexpressing NADPH-cytochrome P450 reductase using 7-Ethoxyresorufin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2019
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50113274BDBM50113274(CHEMBL3601510)
Affinity DataKi:  1.42E+4nMAssay Description:Inhibition of human microsomal CYP1A2-dependent methoxyresorufin-O-demethylase activity by spectrofluorimetric analysis in presence of NADPH regenera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2016
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50236897BDBM50236897(furafylline | 3-(furan-2-ylmethyl)-1,8-dimethyl-1H...)
Affinity DataKi:  2.30E+4nMAssay Description:Mechanism based inhibition of human cytochrome P450 1A2 measured by formation of 6-hydroxywarfarinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50242173BDBM50242173((2S,3S,4S,5R,6S)-6-(5,6-dihydroxy-4-oxo-2-phenyl-4...)
Affinity DataKi:  2.54E+4nMAssay Description:Mixed-type inhibition of CYP1A2 in pooled human liver microsomes using varying levels of phenacetin as substrate pretreated for 5 mins followed by su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2019
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50363928BDBM50363928(CHEMBL1951575)
Affinity DataKi: >3.00E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate after 5 to 30 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50088490BDBM50088490(CHEMBL3526979)
Affinity DataKi: >3.00E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate after 5 to 30 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50240713BDBM50240713(CHEMBL4066318)
Affinity DataKi:  5.46E+4nMAssay Description:Inactivation of CYP1A2 in human liver microsomes after 5 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2019
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50336507BDBM50336507(4-pyridinecarbohydrazide(Isoniazid) | Dow-isoniazi...)
Affinity DataKi:  5.60E+4nMAssay Description:Mechanism based inhibition of human cytochrome P450 1A2 measured by formation of 6-hydroxywarfarinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50418083BDBM50418083(CHEMBL1743359 | ZILEUTON)
Affinity DataKi:  6.60E+4nMAssay Description:Mechanism based inhibition of human cytochrome P450 1A2 measured by phenacetin O-deethylation (POD) More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50236897BDBM50236897(furafylline | 3-(furan-2-ylmethyl)-1,8-dimethyl-1H...)
Affinity DataKi:  6.80E+4nMAssay Description:Inhibition of human microsomal CYP1A2-dependent methoxyresorufin-O-demethylase activity by spectrofluorimetric analysis in presence of NADPH regenera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2016
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50320449BDBM50320449(CHEMBL1164975 | (-)-ZILEUTON)
Affinity DataKi:  9.82E+4nMAssay Description:Mechanism based inhibition of human cytochrome P450 1A2 measured by phenacetin O-deethylation (POD) More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50000541BDBM50000541(Leutrol | CHEMBL93 | N-(1-Benzo(b)thien-2-ylethyl)...)
Affinity DataKi:  1.17E+5nMAssay Description:Mechanism based inhibition of human cytochrome P450 1A2 measured by phenacetin O-deethylation (POD) More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed