Compile Data Set for Download or QSAR
Report error Found 77 of ic50 for UniProtKB: P20831
TargetDNA gyrase subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518940BDBM50518940(CHEMBL4541988)
Affinity DataIC50: 20nMAssay Description:Inhibition of Staphylococcus aureus ATCC 29213 DNA gyrase A assessed as reduction in enzyme-mediated supercoiling of relaxed pBR322 DNA by ethidium b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518915BDBM50518915(CHEMBL4583368)
Affinity DataIC50: 20nMAssay Description:Inhibition of Staphylococcus aureus ATCC 29213 DNA gyrase A assessed as reduction in enzyme-mediated supercoiling of relaxed pBR322 DNA by ethidium b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518948BDBM50518948(CHEMBL4574863)
Affinity DataIC50: 100nMAssay Description:Inhibition of Staphylococcus aureus ATCC 29213 DNA gyrase A assessed as reduction in enzyme-mediated supercoiling of relaxed pBR322 DNA by ethidium b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211505BDBM50211505(CHEMBL3898703)
Affinity DataIC50: 466nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase A expressed in Escherichia coli BL21(DE3) using relaxed pBR322 DNA as substrate incubated for 1 hr by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2018
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211477BDBM50211477(CHEMBL3935890)
Affinity DataIC50: 473nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase A expressed in Escherichia coli BL21(DE3) using relaxed pBR322 DNA as substrate incubated for 1 hr by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2018
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211474BDBM50211474(CHEMBL3889861)
Affinity DataIC50: 524nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase A expressed in Escherichia coli BL21(DE3) using relaxed pBR322 DNA as substrate incubated for 1 hr by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2018
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211475BDBM50211475(CHEMBL3889783)
Affinity DataIC50: 530nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase A expressed in Escherichia coli BL21(DE3) using relaxed pBR322 DNA as substrate incubated for 1 hr by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2018
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211506BDBM50211506(CHEMBL3961159)
Affinity DataIC50: 533nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase A expressed in Escherichia coli BL21(DE3) using relaxed pBR322 DNA as substrate incubated for 1 hr by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2018
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211504BDBM50211504(CHEMBL3979162)
Affinity DataIC50: 537nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase A expressed in Escherichia coli BL21(DE3) using relaxed pBR322 DNA as substrate incubated for 1 hr by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2018
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518911BDBM50518911(CHEMBL4530328)
Affinity DataIC50: 600nMAssay Description:Inhibition of Staphylococcus aureus ATCC 29213 DNA gyrase A assessed as reduction in enzyme-mediated supercoiling of relaxed pBR322 DNA by ethidium b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518925BDBM50518925(CHEMBL4438807)
Affinity DataIC50: 800nMAssay Description:Inhibition of Staphylococcus aureus ATCC 29213 DNA gyrase A assessed as reduction in enzyme-mediated supercoiling of relaxed pBR322 DNA by ethidium b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211507BDBM50211507(CHEMBL3908837)
Affinity DataIC50: 842nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase A expressed in Escherichia coli BL21(DE3) using relaxed pBR322 DNA as substrate incubated for 1 hr by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2018
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211476BDBM50211476(CHEMBL3899795)
Affinity DataIC50: 912nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase A expressed in Escherichia coli BL21(DE3) using relaxed pBR322 DNA as substrate incubated for 1 hr by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2018
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50330317BDBM50330317(5-Methyl-1H-pyrrole-2-carboxylic acid (3R,4S,5R,6S...)
Affinity DataIC50: 929nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase A expressed in Escherichia coli BL21(DE3) using relaxed pBR322 DNA as substrate incubated for 1 hr by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2018
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50393503BDBM50393503(CHEMBL2158050)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase A assessed as reduction in enzyme-mediated supercoiling of relaxed pBR322 DNA measured after 60 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518918BDBM50518918(CHEMBL4569403)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of Staphylococcus aureus ATCC 29213 DNA gyrase A assessed as reduction in enzyme-mediated supercoiling of relaxed pBR322 DNA by ethidium b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518924BDBM50518924(CHEMBL4533152)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of Staphylococcus aureus ATCC 29213 DNA gyrase A assessed as reduction in enzyme-mediated supercoiling of relaxed pBR322 DNA by ethidium b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518922BDBM50518922(CHEMBL4441397)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of Staphylococcus aureus ATCC 29213 DNA gyrase A assessed as reduction in enzyme-mediated supercoiling of relaxed pBR322 DNA by ethidium b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518913BDBM50518913(CHEMBL4575351)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of Staphylococcus aureus ATCC 29213 DNA gyrase A assessed as reduction in enzyme-mediated supercoiling of relaxed pBR322 DNA by ethidium b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518926BDBM50518926(CHEMBL4536608)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of Staphylococcus aureus ATCC 29213 DNA gyrase A assessed as reduction in enzyme-mediated supercoiling of relaxed pBR322 DNA by ethidium b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518941BDBM50518941(CHEMBL4465361)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of Staphylococcus aureus ATCC 29213 DNA gyrase A assessed as reduction in enzyme-mediated supercoiling of relaxed pBR322 DNA by ethidium b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50408209BDBM50408209(CHEMBL4173813)
Affinity DataIC50: 1.92E+3nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase subunit A supercoiling activity using relaxed pBR322 DNA as substrate after 60 mins by agarose gel ele...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518920BDBM50518920(CHEMBL4465692)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of Staphylococcus aureus ATCC 29213 DNA gyrase A assessed as reduction in enzyme-mediated supercoiling of relaxed pBR322 DNA by ethidium b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50408211BDBM50408211(CHEMBL4176073)
Affinity DataIC50: 2.47E+3nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase subunit A supercoiling activity using relaxed pBR322 DNA as substrate after 60 mins by agarose gel ele...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518944BDBM50518944(CHEMBL4537564)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of Staphylococcus aureus ATCC 29213 DNA gyrase A assessed as reduction in enzyme-mediated supercoiling of relaxed pBR322 DNA by ethidium b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518938BDBM50518938(CHEMBL4445613)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of Staphylococcus aureus ATCC 29213 DNA gyrase A assessed as reduction in enzyme-mediated supercoiling of relaxed pBR322 DNA by ethidium b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50483850BDBM50483850(CHEMBL1774147)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase Ser84Leu mutant assessed as inhibition of supercoiling of pBR322 DNA after 60 min by gel electrophores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518935BDBM50518935(CHEMBL4591085)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of Staphylococcus aureus ATCC 29213 DNA gyrase A assessed as reduction in enzyme-mediated supercoiling of relaxed pBR322 DNA by ethidium b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518946BDBM50518946(CHEMBL4548671)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of Staphylococcus aureus ATCC 29213 DNA gyrase A assessed as reduction in enzyme-mediated supercoiling of relaxed pBR322 DNA by ethidium b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518932BDBM50518932(CHEMBL4467826)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of Staphylococcus aureus ATCC 29213 DNA gyrase A assessed as reduction in enzyme-mediated supercoiling of relaxed pBR322 DNA by ethidium b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50330327BDBM50330327((R)-7-(3-(2-aminopropan-2-yl)pyrrolidin-1-yl)-9-cy...)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase Ser84Leu mutant assessed as inhibition of supercoiling of pBR322 DNA after 60 min by gel electrophores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518951BDBM50518951(CHEMBL4570423)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of Staphylococcus aureus ATCC 29213 DNA gyrase A assessed as reduction in enzyme-mediated supercoiling of relaxed pBR322 DNA by ethidium b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518937BDBM50518937(CHEMBL4583024)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of Staphylococcus aureus ATCC 29213 DNA gyrase A assessed as reduction in enzyme-mediated supercoiling of relaxed pBR322 DNA by ethidium b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518933BDBM50518933(CHEMBL4567626)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of Staphylococcus aureus ATCC 29213 DNA gyrase A assessed as reduction in enzyme-mediated supercoiling of relaxed pBR322 DNA by ethidium b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518927BDBM50518927(CHEMBL4549719)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of Staphylococcus aureus ATCC 29213 DNA gyrase A assessed as reduction in enzyme-mediated supercoiling of relaxed pBR322 DNA by ethidium b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50408210BDBM50408210(CHEMBL4167995)
Affinity DataIC50: 6.46E+3nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase subunit A supercoiling activity using relaxed pBR322 DNA as substrate after 60 mins by agarose gel ele...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518910BDBM50518910(CHEMBL4554663)
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of Staphylococcus aureus ATCC 29213 DNA gyrase A assessed as reduction in enzyme-mediated supercoiling of relaxed pBR322 DNA by ethidium b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518912BDBM50518912(CHEMBL4538641)
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of Staphylococcus aureus ATCC 29213 DNA gyrase A assessed as reduction in enzyme-mediated supercoiling of relaxed pBR322 DNA by ethidium b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518952BDBM50518952(CHEMBL4476525)
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of Staphylococcus aureus ATCC 29213 DNA gyrase A assessed as reduction in enzyme-mediated supercoiling of relaxed pBR322 DNA by ethidium b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50408213BDBM50408213(CHEMBL4160460)
Affinity DataIC50: 8.01E+3nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase subunit A supercoiling activity using relaxed pBR322 DNA as substrate after 60 mins by agarose gel ele...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518947BDBM50518947(CHEMBL4527338)
Affinity DataIC50: 9.60E+3nMAssay Description:Inhibition of Staphylococcus aureus ATCC 29213 DNA gyrase A assessed as reduction in enzyme-mediated supercoiling of relaxed pBR322 DNA by ethidium b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518928BDBM50518928(CHEMBL4544202)
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of Staphylococcus aureus ATCC 29213 DNA gyrase A assessed as reduction in enzyme-mediated supercoiling of relaxed pBR322 DNA by ethidium b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50483851BDBM50483851(CHEMBL1774264)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase Ser84Leu mutant assessed as inhibition of supercoiling of pBR322 DNA after 60 min by gel electrophores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518929BDBM50518929(CHEMBL4585210)
Affinity DataIC50: 1.21E+4nMAssay Description:Inhibition of Staphylococcus aureus ATCC 29213 DNA gyrase A assessed as reduction in enzyme-mediated supercoiling of relaxed pBR322 DNA by ethidium b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518936BDBM50518936(CHEMBL4538428)
Affinity DataIC50: 1.21E+4nMAssay Description:Inhibition of Staphylococcus aureus ATCC 29213 DNA gyrase A assessed as reduction in enzyme-mediated supercoiling of relaxed pBR322 DNA by ethidium b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518939BDBM50518939(CHEMBL4531900)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of Staphylococcus aureus ATCC 29213 DNA gyrase A assessed as reduction in enzyme-mediated supercoiling of relaxed pBR322 DNA by ethidium b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21690BDBM21690(Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...)
Affinity DataIC50: 1.49E+4nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase subunit A supercoiling activity using relaxed pBR322 DNA as substrate after 60 mins by agarose gel ele...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDNA gyrase subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50408207BDBM50408207(CHEMBL4171748)
Affinity DataIC50: 1.62E+4nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase subunit A supercoiling activity using relaxed pBR322 DNA as substrate after 60 mins by agarose gel ele...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518917BDBM50518917(CHEMBL4453182)
Affinity DataIC50: 1.69E+4nMAssay Description:Inhibition of Staphylococcus aureus ATCC 29213 DNA gyrase A assessed as reduction in enzyme-mediated supercoiling of relaxed pBR322 DNA by ethidium b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50483849BDBM50483849(CHEMBL1774153)
Affinity DataIC50: 1.87E+4nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase Ser84Leu mutant assessed as inhibition of supercoiling of pBR322 DNA after 60 min by gel electrophores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
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