TargetGenome polyprotein [1424-1463]/[1502-1685](West Nile virus (WNV))
Novartis Institute For Tropical Diseases
Novartis Institute For Tropical Diseases
Affinity DataIC50: 5.20E+3nM Kd: 4.60E+3nMpH: 7.5 T: 2°CAssay Description:Inhibitors were assayed in a 96-well plate format. Typically, protease was preincubated with concentrations of test compounds at 37 deg C for 30 min....More data for this Ligand-Target Pair
TargetGenome polyprotein [1424-1463]/[1502-1685](West Nile virus (WNV))
Novartis Institute For Tropical Diseases
Novartis Institute For Tropical Diseases
Affinity DataIC50: 6.20E+3nM Kd: 7.00E+3nMpH: 7.5 T: 2°CAssay Description:Inhibitors were assayed in a 96-well plate format. Typically, protease was preincubated with concentrations of test compounds at 37 deg C for 30 min....More data for this Ligand-Target Pair
TargetGenome polyprotein [1424-1463]/[1502-1685](West Nile virus (WNV))
Novartis Institute For Tropical Diseases
Novartis Institute For Tropical Diseases
Affinity DataIC50: 1.06E+4nM Kd: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:Inhibitors were assayed in a 96-well plate format. Typically, protease was preincubated with concentrations of test compounds at 37 deg C for 30 min....More data for this Ligand-Target Pair
TargetGenome polyprotein [1424-1463]/[1502-1685](West Nile virus (WNV))
Novartis Institute For Tropical Diseases
Novartis Institute For Tropical Diseases
Affinity DataIC50: 2.20E+4nM Kd: 9.00E+4nMpH: 7.5 T: 2°CAssay Description:Inhibitors were assayed in a 96-well plate format. Typically, protease was preincubated with concentrations of test compounds at 37 deg C for 30 min....More data for this Ligand-Target Pair
TargetGenome polyprotein [1424-1463]/[1502-1685](West Nile virus (WNV))
Novartis Institute For Tropical Diseases
Novartis Institute For Tropical Diseases
Affinity DataIC50: 2.45E+4nM Kd: 2.10E+4nMpH: 7.5 T: 2°CAssay Description:Inhibitors were assayed in a 96-well plate format. Typically, protease was preincubated with concentrations of test compounds at 37 deg C for 30 min....More data for this Ligand-Target Pair
Affinity DataKd: 4.00E+4nMAssay Description:Inhibitory activity against cell free dihydrofolate reductase (DHFR) from Candida albicansMore data for this Ligand-Target Pair
TargetGenome polyprotein [1517-1688]/Mastoparan-2 [1420-1466](West Nile virus (WNV))
University of Zurich
University of Zurich
Affinity DataKd: 1.50E+4nMpH: 7.5 T: 2°CAssay Description:Binding was also measured by a competition assay with a noncovalently bound inhibitor (Kd=4.6 uM) that quenched tryptophan fluorescence upon binding ...More data for this Ligand-Target Pair
TargetGenome polyprotein [1517-1688]/Mastoparan-2 [1420-1466](West Nile virus (WNV))
University of Zurich
University of Zurich
Affinity DataKd: 1.60E+4nMpH: 7.5 T: 2°CAssay Description:Binding was also measured by a competition assay with a noncovalently bound inhibitor (Kd=4.6 uM) that quenched tryptophan fluorescence upon binding ...More data for this Ligand-Target Pair
Affinity DataKd: 4.00E+4nMAssay Description:Binding affinity to West Nile virus NS3 protease by 15N-HSQC 1H NMR analysisMore data for this Ligand-Target Pair
Affinity DataKd: 2.00E+3nMAssay Description:Binding affinity to West Nile virus NS2B-NS3 proteaseMore data for this Ligand-Target Pair
