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TargetDual specificity protein kinase CLK1(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50623175(CHEMBL5424844)
Affinity DataEC50:  250nMAssay Description:Binding affinity to NanoLuc-fused CLK1 (unknown origin) transfected in HEK293T cells assessed as target engagement incubated for 3 hrs by tracer K5 b...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK1(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50235039(CHEMBL3108948)
Affinity DataEC50:  800nMAssay Description:Inhibition of CLK mediated SF3B1 activation in human SK-MEL-2 cells assessed as MDM2-pre mRNA exon skipping after 4 hrs by luciferase reporter gene a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2019
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK1(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50235022(CHEMBL4078898)
Affinity DataEC50:  3.00E+3nMAssay Description:Inhibition of CLK mediated SF3B1 activation in human SK-MEL-2 cells assessed as MDM2-pre mRNA exon skipping after 4 hrs by luciferase reporter gene a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2019
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK1(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50235022(CHEMBL4078898)
Affinity DataEC50:  3.00E+3nMAssay Description:Inhibition of CLK mediated SF3B1 activation in human SK-MEL-2 cells assessed as MDM2-pre mRNA exon skipping after 4 hrs by luciferase reporter gene a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2019
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK1(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50073765(N*2*-((1R,2S)-2-Amino-cyclohexyl)-N*6*-(3-chloro-p...)
Affinity DataEC50:  4.20E+3nMAssay Description:Inhibition of CLK mediated SF3B1 activation in human SK-MEL-2 cells assessed as MDM2-pre mRNA exon skipping after 4 hrs by luciferase reporter gene a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2019
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK1(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50235035(CHEMBL4066861)
Affinity DataEC50:  4.30E+3nMAssay Description:Inhibition of CLK mediated SF3B1 activation in human SK-MEL-2 cells assessed as MDM2-pre mRNA exon skipping after 4 hrs by luciferase reporter gene a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2019
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK1(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50235025(CHEMBL4104505)
Affinity DataEC50:  4.50E+3nMAssay Description:Inhibition of CLK mediated SF3B1 activation in human SK-MEL-2 cells assessed as MDM2-pre mRNA exon skipping after 4 hrs by luciferase reporter gene a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2019
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK1(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50235020(CHEMBL4094492)
Affinity DataEC50:  7.30E+3nMAssay Description:Inhibition of CLK mediated SF3B1 activation in human SK-MEL-2 cells assessed as MDM2-pre mRNA exon skipping after 4 hrs by luciferase reporter gene a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2019
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK1(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50235020(CHEMBL4094492)
Affinity DataEC50:  7.30E+3nMAssay Description:Inhibition of CLK mediated SF3B1 activation in human SK-MEL-2 cells assessed as MDM2-pre mRNA exon skipping after 4 hrs by luciferase reporter gene a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2019
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK1(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50235028(CHEMBL1532768)
Affinity DataEC50:  7.80E+3nMAssay Description:Inhibition of CLK mediated SF3B1 activation in human SK-MEL-2 cells assessed as MDM2-pre mRNA exon skipping after 4 hrs by luciferase reporter gene a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2019
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK1(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50235038(CHEMBL4102202)
Affinity DataEC50:  8.00E+3nMAssay Description:Inhibition of CLK mediated SF3B1 activation in human SK-MEL-2 cells assessed as MDM2-pre mRNA exon skipping after 4 hrs by luciferase reporter gene a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2019
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK1(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50236541(CHEMBL4067661)
Affinity DataEC50:  9.60E+3nMAssay Description:Inhibition of CLK1 (unknown origin) using KKGRSRSRSRSRSR as substrate after 40 mins in presence of [gamma-33P]ATP by microbeta scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK1(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50235032(CHEMBL4100324)
Affinity DataEC50:  9.70E+3nMAssay Description:Inhibition of CLK mediated SF3B1 activation in human SK-MEL-2 cells assessed as MDM2-pre mRNA exon skipping after 4 hrs by luciferase reporter gene a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2019
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK1(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50235024(CHEMBL4088144)
Affinity DataEC50:  1.17E+4nMAssay Description:Inhibition of CLK mediated SF3B1 activation in human SK-MEL-2 cells assessed as MDM2-pre mRNA exon skipping after 4 hrs by luciferase reporter gene a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2019
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK1(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50235040(CHEBI:38937 | AMINOPURVALANOL)
Affinity DataEC50:  1.20E+4nMAssay Description:Inhibition of CLK mediated SF3B1 activation in human SK-MEL-2 cells assessed as MDM2-pre mRNA exon skipping after 4 hrs by luciferase reporter gene a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2019
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK1(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50235037(CHEMBL4102101)
Affinity DataEC50:  1.20E+4nMAssay Description:Inhibition of CLK mediated SF3B1 activation in human SK-MEL-2 cells assessed as MDM2-pre mRNA exon skipping after 4 hrs by luciferase reporter gene a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2019
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK1(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50236540(CHEMBL4080994)
Affinity DataEC50:  1.20E+4nMAssay Description:Inhibition of CLK1 (unknown origin) using KKGRSRSRSRSRSR as substrate after 40 mins in presence of [gamma-33P]ATP by microbeta scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK1(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50235023(CHEMBL4073318)
Affinity DataEC50:  1.22E+4nMAssay Description:Inhibition of CLK mediated SF3B1 activation in human SK-MEL-2 cells assessed as MDM2-pre mRNA exon skipping after 4 hrs by luciferase reporter gene a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2019
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK1(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50235031(CHEMBL4064123)
Affinity DataEC50:  1.29E+4nMAssay Description:Inhibition of CLK mediated SF3B1 activation in human SK-MEL-2 cells assessed as MDM2-pre mRNA exon skipping after 4 hrs by luciferase reporter gene a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2019
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK1(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50235030(CHEMBL4091876)
Affinity DataEC50:  1.40E+4nMAssay Description:Inhibition of CLK mediated SF3B1 activation in human SK-MEL-2 cells assessed as MDM2-pre mRNA exon skipping after 4 hrs by luciferase reporter gene a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2019
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK1(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50235019(CHEMBL4067013)
Affinity DataEC50:  1.75E+4nMAssay Description:Inhibition of CLK mediated SF3B1 activation in human SK-MEL-2 cells assessed as MDM2-pre mRNA exon skipping after 4 hrs by luciferase reporter gene a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2019
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK1(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50235021(CHEMBL4104657)
Affinity DataEC50:  1.87E+4nMAssay Description:Inhibition of CLK mediated SF3B1 activation in human SK-MEL-2 cells assessed as MDM2-pre mRNA exon skipping after 4 hrs by luciferase reporter gene a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2019
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK1(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50235041(CHEMBL1523019)
Affinity DataEC50:  2.00E+4nMAssay Description:Inhibition of CLK mediated SF3B1 activation in human HeLa cells assessed as MDM2-pre mRNA exon skipping by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2019
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK1(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50235026(CHEMBL4080283)
Affinity DataEC50:  2.20E+4nMAssay Description:Inhibition of CLK mediated SF3B1 activation in human SK-MEL-2 cells assessed as MDM2-pre mRNA exon skipping after 4 hrs by luciferase reporter gene a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2019
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK1(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50235036(CHEMBL4082309)
Affinity DataEC50:  2.35E+4nMAssay Description:Inhibition of CLK mediated SF3B1 activation in human SK-MEL-2 cells assessed as MDM2-pre mRNA exon skipping after 4 hrs by luciferase reporter gene a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2019
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK1(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50236546(CHEMBL4065701)
Affinity DataEC50:  2.60E+4nMAssay Description:Inhibition of CLK1 (unknown origin) using KKGRSRSRSRSRSR as substrate after 40 mins in presence of [gamma-33P]ATP by microbeta scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK1(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50235029(CHEMBL4084116)
Affinity DataEC50:  2.64E+4nMAssay Description:Inhibition of CLK mediated SF3B1 activation in human SK-MEL-2 cells assessed as MDM2-pre mRNA exon skipping after 4 hrs by luciferase reporter gene a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2019
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK1(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50236550(CHEMBL4105239)
Affinity DataEC50:  3.40E+4nMAssay Description:Inhibition of CLK1 (unknown origin) using KKGRSRSRSRSRSR as substrate after 40 mins in presence of [gamma-33P]ATP by microbeta scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK1(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50236544(CHEMBL4096575)
Affinity DataEC50:  3.40E+4nMAssay Description:Inhibition of CLK1 (unknown origin) using KKGRSRSRSRSRSR as substrate after 40 mins in presence of [gamma-33P]ATP by microbeta scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK1(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50236543(CHEMBL4078550)
Affinity DataEC50:  3.50E+4nMAssay Description:Inhibition of CLK1 (unknown origin) using KKGRSRSRSRSRSR as substrate after 40 mins in presence of [gamma-33P]ATP by microbeta scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK1(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50236542(CHEMBL4088888)
Affinity DataEC50:  4.40E+4nMAssay Description:Inhibition of CLK1 (unknown origin) using KKGRSRSRSRSRSR as substrate after 40 mins in presence of [gamma-33P]ATP by microbeta scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK1(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50445231(CHEMBL3102950)
Affinity DataEC50:  4.80E+4nMAssay Description:Inhibition of CLK1 (unknown origin) using KKGRSRSRSRSRSR as substrate after 40 mins in presence of [gamma-33P]ATP by microbeta scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK1(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50236545(CHEMBL4087125)
Affinity DataEC50:  7.00E+4nMAssay Description:Inhibition of CLK1 (unknown origin) using KKGRSRSRSRSRSR as substrate after 40 mins in presence of [gamma-33P]ATP by microbeta scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK1(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50236536(CHEMBL4102553)
Affinity DataEC50:  8.50E+4nMAssay Description:Inhibition of CLK1 (unknown origin) using KKGRSRSRSRSRSR as substrate after 40 mins in presence of [gamma-33P]ATP by microbeta scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK1(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50236537(CHEMBL4084605)
Affinity DataEC50:  1.17E+5nMAssay Description:Inhibition of CLK1 (unknown origin) using KKGRSRSRSRSRSR as substrate after 40 mins in presence of [gamma-33P]ATP by microbeta scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK1(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50236547(CHEMBL4075959)
Affinity DataEC50:  1.87E+5nMAssay Description:Inhibition of CLK1 (unknown origin) using KKGRSRSRSRSRSR as substrate after 40 mins in presence of [gamma-33P]ATP by microbeta scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK1(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50236549(CHEMBL4070354)
Affinity DataEC50: >1.00E+6nMAssay Description:Inhibition of CLK1 (unknown origin) using KKGRSRSRSRSRSR as substrate after 40 mins in presence of [gamma-33P]ATP by microbeta scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK1(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50236539(CHEMBL4073972)
Affinity DataEC50: >1.00E+6nMAssay Description:Inhibition of CLK1 (unknown origin) using KKGRSRSRSRSRSR as substrate after 40 mins in presence of [gamma-33P]ATP by microbeta scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK1(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50236548(CHEMBL4097535)
Affinity DataEC50: >1.00E+6nMAssay Description:Inhibition of CLK1 (unknown origin) using KKGRSRSRSRSRSR as substrate after 40 mins in presence of [gamma-33P]ATP by microbeta scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK1(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50236551(CHEMBL4092345)
Affinity DataEC50: >1.00E+6nMAssay Description:Inhibition of CLK1 (unknown origin) using KKGRSRSRSRSRSR as substrate after 40 mins in presence of [gamma-33P]ATP by microbeta scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK1(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50236538(CHEMBL4083661)
Affinity DataEC50: >1.00E+6nMAssay Description:Inhibition of CLK1 (unknown origin) using KKGRSRSRSRSRSR as substrate after 40 mins in presence of [gamma-33P]ATP by microbeta scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed