Compile Data Set for Download or QSAR
maximum 50k data
Found 10 of ki for UniProtKB: P70627
TargetGlutamate carboxypeptidase 2(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM17659((R,S)-2-phosphonomethylpentanedioic acid | 2-(phos...)
Affinity DataKi:  0.275nMAssay Description:Compound was tested for inhibition of the Folate hydrolaseMore data for this Ligand-Target Pair
TargetGlutamate carboxypeptidase 2(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50048694(2-[(2-Carboxy-ethyl)-hydroxy-phosphinoylmethyl]-pe...)
Affinity DataKi:  1.90nMAssay Description:Compound was tested for inhibition of the Folate hydrolaseMore data for this Ligand-Target Pair
TargetGlutamate carboxypeptidase 2(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50014185(2-(3-Carboxy-acryloylamino)-pentanedioic acid | CH...)
Affinity DataKi:  400nMAssay Description:Tested for Ac-Asp-[3,4-3H]-Glu-OH hydrolysis inhibitory activity against rat fore-brain N-acetylated-alpha-linked acidic dipeptidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate carboxypeptidase 2(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50048693(2-Phosphonomethyl-succinic acid | 2-Phosphonomethy...)
Affinity DataKi:  700nMAssay Description:Compound was tested for inhibition of the Folate hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate carboxypeptidase 2(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50014184(2-(2-Carboxy-acetylamino)-pentanedioic acid | CHEM...)
Affinity DataKi:  900nMAssay Description:Tested for Ac-Asp-[3,4-3H]-Glu-OH hydrolysis inhibitory activity against rat fore-brain N-acetylated-alpha-linked acidic dipeptidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate carboxypeptidase 2(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50014188(2-(3-Carboxy-2-methoxycarbonylamino-acryloylamino)...)
Affinity DataKi:  1.40E+3nMAssay Description:Tested for Ac-Asp-[3,4-3H]-Glu-OH hydrolysis inhibitory activity against rat fore-brain N-acetylated-alpha-linked acidic dipeptidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate carboxypeptidase 2(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50014187(2-(3-Acetylamino-4-carboxy-butyrylamino)-pentanedi...)
Affinity DataKi:  3.20E+3nMAssay Description:Tested for Ac-Asp-[3,4-3H]-Glu-OH hydrolysis inhibitory activity against rat fore-brain N-acetylated-alpha-linked acidic dipeptidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate carboxypeptidase 2(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50014182(2-(2-Acetylamino-4-carboxy-butyrylamino)-pentanedi...)
Affinity DataKi:  3.50E+3nMAssay Description:Tested for Ac-Asp-[3,4-3H]-Glu-OH hydrolysis inhibitory activity against rat fore-brain N-Acetylated alpha-linked Dipeptidase (NAALA Dipeptidase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate carboxypeptidase 2(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50014180(2-(2-Acetylamino-3-carboxy-propionylamino)-pentane...)
Affinity DataKi:  8.50E+3nMAssay Description:Concentration required for 50%inhibition of Ac-Asp-[3,4-3H]-Glu-OH hydrolysis against rat fore-brain N-Acetylated alpha-linked Dipeptidase (NAALA Dip...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate carboxypeptidase 2(Rattus norvegicus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50014181(2-(3-Carboxy-acryloylamino)-pentanedioic acid | CH...)
Affinity DataKi:  4.10E+4nMAssay Description:Concentration required for 50%inhibition of Ac-Asp-[3,4-3H]-Glu-OH hydrolysis against rat fore-brain N-acetylated-alpha-linked acidic dipeptidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed