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Found 24 of ic50 for UniProtKB: P31214
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Rattus norvegicus)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50334788((17beta-(N-tert-butylcarbamoyl)-4-aza-5alpha-andro...)
Affinity DataIC50:  0.280nMAssay Description:Inhibitory activity was measured on rat Steroid 5-alpha-reductase type 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Rattus norvegicus)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50589275(CHEMBL5190333)
Affinity DataIC50:  4nMAssay Description:Inhibition of rat liver microsomal SRD5A2 incubated for 60 mins by thin layer chromatographyMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Rattus norvegicus)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50334788((17beta-(N-tert-butylcarbamoyl)-4-aza-5alpha-andro...)
Affinity DataIC50:  11nMAssay Description:Inhibition of Steroid 5-alpha-reductase type 2 of rat ventral prostate (RVP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Rattus norvegicus)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50517901(CHEMBL4540042)
Affinity DataIC50:  15nMAssay Description:Inhibition of type 2 5alpha reductase in rat prostateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Rattus norvegicus)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50334788((17beta-(N-tert-butylcarbamoyl)-4-aza-5alpha-andro...)
Affinity DataIC50:  32nMAssay Description:Inhibition of type 2 5alpha reductase in rat prostateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Rattus norvegicus)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50517880(CHEMBL4569322)
Affinity DataIC50:  34nMAssay Description:Inhibition of type 2 5alpha reductase in rat prostateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Rattus norvegicus)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50116424(CHEMBL115438 | {4-[1-(2,2-Dicyclohexyl-acetyl)-pip...)
Affinity DataIC50:  38nMAssay Description:Inhibition of Steroid 5-alpha-reductase type 2 of rat ventral prostate (RVP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Rattus norvegicus)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50116429(4-[1-(2,2-Dicyclohexyl-acetyl)-piperidin-4-ylidene...)
Affinity DataIC50:  80nMAssay Description:Inhibition of Steroid 5-alpha-reductase type 2 of rat ventral prostate (RVP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Rattus norvegicus)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50344122((N-tert-butyl-N-((4aR,4bS,6aS,7S,9aS,9bS)-4a,6a-di...)
Affinity DataIC50:  88.0nMAssay Description:Inhibition of rat 5-alpha-reductase type 2 by Lineweaver-Burk plotMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Rattus norvegicus)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50462940(CHEMBL4244937)
Affinity DataIC50:  127nMAssay Description:Inhibition of rat liver microsomal SRD5A2 incubated for 60 mins by thin layer chromatographyMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Rattus norvegicus)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50334788((17beta-(N-tert-butylcarbamoyl)-4-aza-5alpha-andro...)
Affinity DataIC50:  147nMAssay Description:Inhibition of rat 5-alpha-reductase type 2 by Lineweaver-Burk plotMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Rattus norvegicus)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50057482(4-(2-{4-[(S)-1-(4-Isobutyl-phenyl)-ethoxy]-2,3-dim...)
Affinity DataIC50:  180nMAssay Description:Compound was tested in vitro for inhibitory activity against type 1 5-alpha reductase Isozyme homogenated from rat epididymisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Rattus norvegicus)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50032297(4-[2-((E)-3-{1-[Bis-(4-fluoro-phenyl)-methyl]-1H-i...)
Affinity DataIC50:  210nMAssay Description:Compound was tested in vitro for inhibitory activity against type 2 5-alpha reductase isozyme homogenated from rat epididymisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Rattus norvegicus)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50055150(4-[2-((E)-3-{1-[Bis-(4-fluoro-phenyl)-methyl]-1H-i...)
Affinity DataIC50:  280nMAssay Description:Compound was tested in vitro for inhibitory activity against type 2 5-alpha reductase Isozyme homogenated from rat epididymisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Rattus norvegicus)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50116423(4-(1-Diphenylacetyl-piperidin-4-ylidenemethyl)-ben...)
Affinity DataIC50:  370nMAssay Description:Inhibition of Steroid 5-alpha-reductase type 2 of rat ventral prostate (RVP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Rattus norvegicus)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50116417(4-(1-Diphenylcarbamoyl-piperidin-4-ylidenemethyl)-...)
Affinity DataIC50:  690nMAssay Description:Inhibition of Steroid 5-alpha-reductase type 2 of rat ventral prostate (RVP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Rattus norvegicus)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50055148(4-(2-{(E)-3-[1-(1-Propyl-butyl)-1H-indol-5-yl]-pen...)
Affinity DataIC50:  750nMAssay Description:Compound was tested in vitro for inhibitory activity against type 2 5-alpha reductase Isozyme homogenated from rat epididymisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Rattus norvegicus)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50116422(4-[1-(3,3-Diphenyl-propionyl)-piperidin-4-ylidenem...)
Affinity DataIC50:  880nMAssay Description:Inhibition of Steroid 5-alpha-reductase type 2 of rat ventral prostate (RVP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Rattus norvegicus)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50116428(4-(1-Diphenylacetyl-piperidin-4-ylidenemethyl)-3-m...)
Affinity DataIC50:  940nMAssay Description:Inhibition of Steroid 5-alpha-reductase type 2 of rat ventral prostate (RVP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Rattus norvegicus)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50116432(4-(1-Diphenylacetyl-piperidin-4-ylidenemethyl)-3-f...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of Steroid 5-alpha-reductase type 2 of rat ventral prostate (RVP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Rattus norvegicus)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50334788((17beta-(N-tert-butylcarbamoyl)-4-aza-5alpha-andro...)
Affinity DataIC50:  2.10E+3nMAssay Description:Compound was tested in vitro for inhibitory activity against type 2 5-alpha reductase Isozyme homogenated from rat epididymisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Rattus norvegicus)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50116426(4-[1-(Adamantane-1-carbonyl)-piperidin-4-ylideneme...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of Steroid 5-alpha-reductase type 2 of rat ventral prostate (RVP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Rattus norvegicus)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50116419(4-[1-(2,2-Dicyclohexyl-acetyl)-piperidin-4-ylidene...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of Steroid 5-alpha-reductase type 2 of rat ventral prostate (RVP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Rattus norvegicus)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50116416(4-[1-(Adamantane-1-carbonyl)-piperidin-4-ylideneme...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of Steroid 5-alpha-reductase type 2 of rat ventral prostate (RVP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed