BindingDB PrimarySearch_ki

Found 379 of ic50 for UniProtKB: P03433

Polymerase acidic protein(Hepatitis C virus)
University Of California

Curated by ChEMBL

PNG

BDBM50509167(CHEMBL4539596)

IC50: >2nMAssay Description:Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

PC cid PC sid PDB

Details Article PubMed PDB

3D Structure (crystal)

Polymerase acidic protein(Hepatitis C virus)
University Of California

Curated by ChEMBL

PNG

BDBM50509169(CHEMBL4545631)

IC50: >2nMAssay Description:Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

PC cid PC sid PDB

Details Article PubMed PDB

3D Structure (crystal)

Polymerase acidic protein(Hepatitis C virus)
University Of California

Curated by ChEMBL

PNG

BDBM50509169(CHEMBL4545631)

IC50: <2nMAssay Description:Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

PC cid PC sid PDB

Details Article PubMed PDB

3D Structure (crystal)

Polymerase acidic protein(Hepatitis C virus)
University Of California

Curated by ChEMBL

PNG

BDBM50509167(CHEMBL4539596)

IC50: <2nMAssay Description:Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

PC cid PC sid PDB

Details Article PubMed PDB

3D Structure (crystal)

Polymerase acidic protein(Hepatitis C virus)
University Of California

Curated by ChEMBL

PNG

BDBM50509165(CHEMBL4459575)

IC50: <2nMAssay Description:Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Details Article PubMed

Polymerase acidic protein(Hepatitis C virus)
University Of California

Curated by ChEMBL

PNG

BDBM50509161(CHEMBL4563716)

IC50: >2nMAssay Description:Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

PC cid PC sid PDB

Details Article PubMed PDB

3D Structure (crystal)

Polymerase acidic protein(Hepatitis C virus)
University Of California

Curated by ChEMBL

PNG

BDBM50509155(CHEMBL4440123)

IC50: >2nMAssay Description:Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Details Article PubMed

Polymerase acidic protein(Hepatitis C virus)
University Of California

Curated by ChEMBL

PNG

BDBM50509159(CHEMBL4588964)

IC50: >2nMAssay Description:Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Details Article PubMed

Polymerase acidic protein(Hepatitis C virus)
University Of California

Curated by ChEMBL

PNG

BDBM50509161(CHEMBL4563716)

IC50: <2nMAssay Description:Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

PC cid PC sid PDB

Details Article PubMed PDB

3D Structure (crystal)

Polymerase acidic protein(Hepatitis C virus)
University Of California

Curated by ChEMBL

PNG

BDBM50509159(CHEMBL4588964)

IC50: <2nMAssay Description:Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Details Article PubMed

Polymerase acidic protein(Hepatitis C virus)
University Of California

Curated by ChEMBL

PNG

BDBM50509155(CHEMBL4440123)

IC50: <2nMAssay Description:Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Details Article PubMed

Polymerase acidic protein(Hepatitis C virus)
University Of California

Curated by ChEMBL

PNG

BDBM50509165(CHEMBL4459575)

IC50: >2nMAssay Description:Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Details Article PubMed

Polymerase acidic protein(Hepatitis C virus)
University Of California

Curated by ChEMBL

PNG

BDBM50509160(CHEMBL4570983)

IC50: 2.30nMAssay Description:Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Details Article PubMed

Polymerase acidic protein(Hepatitis C virus)
University Of California

Curated by ChEMBL

PNG

BDBM50509170(CHEMBL4440338)

IC50: 2.30nMAssay Description:Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

PC cid PC sid PDB

Details Article PubMed PDB

3D Structure (crystal)

Polymerase acidic protein(Hepatitis C virus)
University Of California

Curated by ChEMBL

PNG

BDBM50509170(CHEMBL4440338)

IC50: 2.5nMAssay Description:Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

PC cid PC sid PDB

Details Article PubMed PDB

3D Structure (crystal)

Polymerase acidic protein(Hepatitis C virus)
University Of California

Curated by ChEMBL

PNG

BDBM50509160(CHEMBL4570983)

IC50: 2.5nMAssay Description:Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Details Article PubMed

Polymerase acidic protein(Hepatitis C virus)
University Of California

Curated by ChEMBL

PNG

BDBM50509166(CHEMBL4550646)

IC50: 3.20nMAssay Description:Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Details Article PubMed

Polymerase acidic protein(Hepatitis C virus)
University Of California

Curated by ChEMBL

PNG

BDBM50509157(CHEMBL4530222)

IC50: 3.20nMAssay Description:Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Details Article PubMed

Polymerase acidic protein(Hepatitis C virus)
University Of California

Curated by ChEMBL

PNG

BDBM50509157(CHEMBL4530222)

IC50: 3.20nMAssay Description:Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Details Article PubMed

Polymerase acidic protein(Hepatitis C virus)
University Of California

Curated by ChEMBL

PNG

BDBM50509166(CHEMBL4550646)

IC50: 3.20nMAssay Description:Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Details Article PubMed

Polymerase acidic protein(Hepatitis C virus)
University Of California

Curated by ChEMBL

PNG

BDBM50509172(CHEMBL4553243)

IC50: 4.80nMAssay Description:Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Details Article PubMed

Polymerase acidic protein(Hepatitis C virus)
University Of California

Curated by ChEMBL

PNG

BDBM50509172(CHEMBL4553243)

IC50: 5nMAssay Description:Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Details Article PubMed

Polymerase acidic protein(Hepatitis C virus)
University Of California

Curated by ChEMBL

PNG

BDBM50508967(CHEMBL3944613)

IC50: 5nMAssay Description:Inhibition of Influenza A virus CENMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

PC cid PC sid PDB

Details Article PubMed

Polymerase acidic protein(Hepatitis C virus)
University Of California

Curated by ChEMBL

PNG

BDBM50509173(CHEMBL4469796)

IC50: 5.60nMAssay Description:Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Details Article PubMed

Polymerase acidic protein(Hepatitis C virus)
University Of California

Curated by ChEMBL

PNG

BDBM50509173(CHEMBL4469796)

IC50: 5.60nMAssay Description:Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Details Article PubMed

Polymerase acidic protein(Hepatitis C virus)
University Of California

Curated by ChEMBL

PNG

BDBM50509168(CHEMBL4460007)

IC50: 6nMAssay Description:Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Details Article PubMed

Polymerase acidic protein(Hepatitis C virus)
University Of California

Curated by ChEMBL

PNG

BDBM50509154(CHEMBL4453833)

IC50: 6.30nMAssay Description:Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Details Article PubMed

Polymerase acidic protein(Hepatitis C virus)
University Of California

Curated by ChEMBL

PNG

BDBM50509154(CHEMBL4453833)

IC50: 6.30nMAssay Description:Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Details Article PubMed

Polymerase acidic protein(Hepatitis C virus)
University Of California

Curated by ChEMBL

PNG

BDBM50509168(CHEMBL4460007)

IC50: 6.30nMAssay Description:Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Details Article PubMed

Polymerase acidic protein(Hepatitis C virus)
University Of California

Curated by ChEMBL

PNG

BDBM50509152(CHEMBL4535893)

IC50: 7.20nMAssay Description:Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Details Article PubMed

Polymerase acidic protein(Hepatitis C virus)
University Of California

Curated by ChEMBL

PNG

BDBM50509152(CHEMBL4535893)

IC50: 7.90nMAssay Description:Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Details Article PubMed

Polymerase acidic protein(Hepatitis C virus)
University Of California

Curated by ChEMBL

PNG

BDBM105203(6-(4-Fluorophenyl)-3-hydroxy-5-[4-(1H-1, 2, 3, 4-t...)

IC50: 11nMAssay Description:Inhibition of Influenza A virus CENMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

MMDB PC cid PC sid Similars

Details Article PubMed

Polymerase acidic protein(Hepatitis C virus)
University Of California

Curated by ChEMBL

PNG

BDBM105203(6-(4-Fluorophenyl)-3-hydroxy-5-[4-(1H-1, 2, 3, 4-t...)

IC50: 11nMAssay Description:Inhibition of Influenza A/Puerto Rico/8/34 (H1N1) PA N-terminal domain endonuclease activity expressed in Escherichia coli BL21 (RIL) cells using (6-...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

MMDB PC cid PC sid Similars

Details Article PubMed

Polymerase acidic protein(Hepatitis C virus)
University Of California

Curated by ChEMBL

PNG

BDBM50409783(CHEMBL1626982 | CHEMBL2068710 | CHEMBL2068711 | CH...)

IC50: 12nMAssay Description:Inhibitory concentration against cap-dependent endonuclease activity of influenza A/PR/8/34 RNPMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL KEGG PC cid PC sid Similars

Details Article PubMed

Polymerase acidic protein(Hepatitis C virus)
University Of California

Curated by ChEMBL

PNG

BDBM50509158(CHEMBL4438546)

IC50: 13nMAssay Description:Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Details Article PubMed

Polymerase acidic protein(Hepatitis C virus)
University Of California

Curated by ChEMBL

PNG

BDBM50508966(CHEMBL4452342)

IC50: 13nMAssay Description:Inhibition of 8-histidine tagged influenza virus H1N1 N-terminal PA endonuclease expressed in Escherichia coli BL21 cells using single-stranded 5'-FA...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Details Article PubMed

Polymerase acidic protein(Hepatitis C virus)
University Of California

Curated by ChEMBL

PNG

BDBM50508966(CHEMBL4452342)

IC50: 14nMAssay Description:Inhibition of Influenza A virus CENMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Details Article PubMed

Polymerase acidic protein(Hepatitis C virus)
University Of California

Curated by ChEMBL

PNG

BDBM50509158(CHEMBL4438546)

IC50: 14nMAssay Description:Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Details Article PubMed

Polymerase acidic protein(Hepatitis C virus)
University Of California

Curated by ChEMBL

PNG

BDBM50508966(CHEMBL4452342)

IC50: 14nMAssay Description:Inhibition of 8-histidine tagged influenza virus H1N1 N-terminal PA endonuclease expressed in Escherichia coli BL21 cells using single-stranded 5'-FA...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Details Article PubMed

Polymerase acidic protein(Hepatitis C virus)
University Of California

Curated by ChEMBL

PNG

BDBM50509156(CHEMBL4170746)

IC50: 16nMAssay Description:Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Purchase PC cid PC sid PDB

Details Article PubMed PDB

3D Structure (crystal)

Polymerase acidic protein(Hepatitis C virus)
University Of California

Curated by ChEMBL

PNG

BDBM50509156(CHEMBL4170746)

IC50: 17nMAssay Description:Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Purchase PC cid PC sid PDB

Details Article PubMed PDB

3D Structure (crystal)

Polymerase acidic protein(Hepatitis C virus)
University Of California

Curated by ChEMBL

PNG

BDBM50509171(CHEMBL4476501)

IC50: 25nMAssay Description:Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Details Article PubMed

Polymerase acidic protein(Hepatitis C virus)
University Of California

Curated by ChEMBL

PNG

BDBM50509171(CHEMBL4476501)

IC50: 25nMAssay Description:Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Details Article PubMed

Polymerase acidic protein(Hepatitis C virus)
University Of California

Curated by ChEMBL

PNG

BDBM50409783(CHEMBL1626982 | CHEMBL2068710 | CHEMBL2068711 | CH...)

IC50: 31nMAssay Description:Inhibitory concentration against cap-dependent endonuclease activity of influenza A/PR/8/34 RNPMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL KEGG PC cid PC sid Similars

Details Article PubMed

Polymerase acidic protein(Hepatitis C virus)
University Of California

Curated by ChEMBL

PNG

BDBM50536153(CHEMBL4531327)

IC50: 36nMAssay Description:Inhibition of 8-histidine tagged influenza virus H1N1 N-terminal PA endonuclease expressed in Escherichia coli BL21 cells using single-stranded 5'-FA...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

PC cid PC sid PDB

Details Article PubMed PDB

3D Structure (crystal)

Polymerase acidic protein(Hepatitis C virus)
University Of California

Curated by ChEMBL

PNG

BDBM50536153(CHEMBL4531327)

IC50: 36nMAssay Description:Inhibition of 8-histidine tagged influenza virus H1N1 N-terminal PA endonuclease expressed in Escherichia coli BL21 cells using single-stranded 5'-FA...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

PC cid PC sid PDB

Details Article PubMed PDB

3D Structure (crystal)

Polymerase acidic protein(Hepatitis C virus)
University Of California

Curated by ChEMBL

PNG

BDBM50509153(CHEMBL4551356)

IC50: 47nMAssay Description:Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Details Article PubMed

Polymerase acidic protein(Hepatitis C virus)
University Of California

Curated by ChEMBL

PNG

BDBM50509153(CHEMBL4551356)

IC50: 47nMAssay Description:Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Details Article PubMed

Polymerase acidic protein(Hepatitis C virus)
University Of California

Curated by ChEMBL

PNG

BDBM50508959(CHEMBL4439208)

IC50: 48nMAssay Description:Inhibition of Influenza A virus (A/WSN/1933(H1N1)) CEN using m7G[5']-ppp-[5'] [m2'-O]GAA UAU(-Cy3) GCA UCA CUA GUA AGC UUU GCU CUA(-BHQ2)-3' as subst...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Details Article PubMed

Polymerase acidic protein(Hepatitis C virus)
University Of California

Curated by ChEMBL

PNG

BDBM50508952(CHEMBL4513495)

IC50: 80nMAssay Description:Inhibition of Influenza A virus (A/WSN/1933(H1N1)) CEN using m7G[5']-ppp-[5'] [m2'-O]GAA UAU(-Cy3) GCA UCA CUA GUA AGC UUU GCU CUA(-BHQ2)-3' as subst...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Details Article PubMed

Displayed 1 to 50 (of 379 total ) | Next | Last >>

Filter my 379 hits

Targets 1▿
- Polymerase acidic protein 379
Publications 12▿
- J Med Chem 59: 6444-54 (2016) 142
- J Med Chem 46: 1153-64 (2003) 55
- J Med Chem 62: 9438-9449 (2019) 44
- J Org Chem 66: 5504-16 (2001) 42
- J Med Chem 62: 8101-8114 (2019) 31
- Antimicrob Agents Chemother 38: 2827-37 (1995) 20
- Eur J Med Chem 161: 526-532 (2019) 12
- J Med Chem 60: 3533-3551 (2017) 11
- Eur J Med Chem 227: (2022) 9
- Antimicrob Agents Chemother 40: 1304-7 (1996) 8
- Bioorg Med Chem 23: 5466-75 (2015) 4
- Bioorg Med Chem 16: 4203-21 (2008) 1
Institutions 10▿
- University Of California San Diego 142
- Merck Research Laboratories 70
- Roche Discovery Welwyn 55
- University Of California 44
- Shionogi 31
- Saint Petersburg State University 12
- Shandong University 11
- South China Agricultural University 9
- Chiba University 4
- University Of Bayreuth 1
Affinity: 2 to 1.0E+6 nM▿
- IC50 379
- Affinity ≤ nM
Xtal structures: 16
Docked structures: 0
Catalog Cmpds: 33