Compile Data Set for Download or QSAR
Report error Found 139 of kd for UniProtKB: P29320
TargetEphrin type-A receptor 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 13216BDBM13216(N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyeth...)
Affinity DataKd:  0.0930nMAssay Description:Binding constant for EPHA3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEphrin type-A receptor 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 13216BDBM13216(N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyeth...)
Affinity DataKd:  0.0930nMAssay Description:Binding constant for EPHA3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEphrin type-A receptor 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 26145BDBM26145(CHEMBL249097 | 3-({4-[(5-hydroxy-2-methylphenyl)am...)
Affinity DataKd:  0.100nMAssay Description:Binding affinity to human EPHA3More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEphrin type-A receptor 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50355504BDBM50355504(CHEMBL1908393)
Affinity DataKd:  1nMAssay Description:Binding constant for EPHA3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetEphrin type-A receptor 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 4552BDBM4552(CHEMBL288441 | SKI-606 | 4-[(2,4-Dichloro-5-methox...)
Affinity DataKd:  5.80nMAssay Description:Binding constant for EPHA3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetEphrin type-A receptor 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 6568BDBM6568(PD-173955 | CHEMBL386051 | 6-(2,6-dichlorophenyl)-...)
Affinity DataKd:  7.60nMAssay Description:Binding constant for EPHA3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetEphrin type-A receptor 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100316BDBM50100316(CHEMBL3321809)
Affinity DataKd:  8.60nMAssay Description:Binding affinity to EphA3 (unknown origin) by surface plasmon resonanceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMed
TargetEphrin type-A receptor 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621890BDBM50621890(CHEMBL5415503)
Affinity DataKd:  23nMAssay Description:Binding affinity to EPHA3 (unknown origin) assessed as dissociation constant by KINOME scan assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetEphrin type-A receptor 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 2579BDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataKd:  27nMAssay Description:Binding constant for EPHA3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetEphrin type-A receptor 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 2579BDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataKd:  27nMAssay Description:Binding constant for EPHA3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetEphrin type-A receptor 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100317BDBM50100317(CHEMBL3321822)
Affinity DataKd:  39.3nMAssay Description:Binding affinity to EphA3 (unknown origin) by surface plasmon resonanceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMed
TargetEphrin type-A receptor 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50263295BDBM50263295(6-Methyl-biphenyl-3,4'-dicarboxylic acid 3-[(3-ter...)
Affinity DataKd:  46nMAssay Description:Binding affinity to human EPHA3More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEphrin type-A receptor 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 2579BDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataKd:  55nMAssay Description:Average Binding Constant for EPHA3; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEphrin type-A receptor 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 31085BDBM31085(cid_11409972 | 1-[4-[(4-ethylpiperazin-1-yl)methyl...)
Affinity DataKd:  80nMAssay Description:Binding constant for EPHA3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetEphrin type-A receptor 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 31085BDBM31085(cid_11409972 | 1-[4-[(4-ethylpiperazin-1-yl)methyl...)
Affinity DataKd:  80nMAssay Description:Binding constant for EPHA3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetEphrin type-A receptor 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50237710BDBM50237710(AMN 107 | AMN107 | 4-methyl-N-[3-(4-methyl-1H-imid...)
Affinity DataKd:  110nMAssay Description:Binding constant for EPHA3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetEphrin type-A receptor 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50308060BDBM50308060(CEP-701 | 16-hydroxy-16-(hydroxymethyl)-15-methyl-...)
Affinity DataKd:  160nMAssay Description:Binding affinity to EPHA3More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetEphrin type-A receptor 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50308060BDBM50308060(CEP-701 | 16-hydroxy-16-(hydroxymethyl)-15-methyl-...)
Affinity DataKd:  160nMAssay Description:Binding constant for EPHA3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetEphrin type-A receptor 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50587767BDBM50587767(CHEMBL5172097)
Affinity DataKd:  250nMAssay Description:Inhibition of EPHA3 (unknown origin) assessed as dissociation constant by ELISA-like binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetEphrin type-A receptor 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 60665BDBM60665(US9145414, R406 | US9212178, R406 | BDBM50249542 |...)
Affinity DataKd:  360nMAssay Description:Binding constant for EPHA3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetEphrin type-A receptor 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 36409BDBM36409(CID24905147 | 2-(4-amino-1-isopropyl-1H-pyrazolo[3...)
Affinity DataKd:  390nMAssay Description:Binding constant for EPHA3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetEphrin type-A receptor 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 13533BDBM13533(1-[5-tert-butyl-2-(p-tolyl)pyrazol-3-yl]-3-[4-(2-m...)
Affinity DataKd:  580nMAssay Description:Average Binding Constant for EPHA3; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEphrin type-A receptor 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 4779BDBM4779(cid_156414 | PD0183805 | CHEMBL545315 | CHEMBL3196...)
Affinity DataKd:  650nMAssay Description:Average Binding Constant for EPHA3; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEphrin type-A receptor 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306682BDBM50306682((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)
Affinity DataKd:  700nMAssay Description:Binding constant for EPHA3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetEphrin type-A receptor 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50505541BDBM50505541(CHEMBL4465866)
Affinity DataKd:  747nMAssay Description:Binding affinity to recombinant N-terminal His-FLAG-GST-tagged EPHA3 (unknown origin) (579 to 983 residues) expressed in baculovirus infected Sf9 ins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetEphrin type-A receptor 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50355496BDBM50355496(CHEMBL1908397)
Affinity DataKd:  810nMAssay Description:Binding constant for EPHA3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetEphrin type-A receptor 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 13533BDBM13533(1-[5-tert-butyl-2-(p-tolyl)pyrazol-3-yl]-3-[4-(2-m...)
Affinity DataKd:  880nMAssay Description:Binding constant for EPHA3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetEphrin type-A receptor 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 13533BDBM13533(1-[5-tert-butyl-2-(p-tolyl)pyrazol-3-yl]-3-[4-(2-m...)
Affinity DataKd:  880nMAssay Description:Binding constant for EPHA3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetEphrin type-A receptor 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 13534BDBM13534(VX680 | N-[4-[[4-(4-methylpiperazino)-6-[(5-methyl...)
Affinity DataKd:  1.50E+3nMAssay Description:Binding constant for EPHA3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetEphrin type-A receptor 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50572065BDBM50572065(CHEMBL4878061)
Affinity DataKd:  1.50E+3nMAssay Description:Binding affinity to N-terminal His tagged EphA3 LBD (unknown origin) expressed in Rosetta-Gami B(DE3) cells by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetEphrin type-A receptor 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 13534BDBM13534(VX680 | N-[4-[[4-(4-methylpiperazino)-6-[(5-methyl...)
Affinity DataKd:  1.50E+3nMAssay Description:Binding constant for EPHA3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetEphrin type-A receptor 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50355499BDBM50355499(CHEMBL1908395 | CHEMBL1908842 | US20250129067, Com...)
Affinity DataKd:  1.60E+3nMAssay Description:Binding constant for EPHA3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetEphrin type-A receptor 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21BDBM21(VANDETANIB | N-(4-bromo-2-fluorophenyl)-6-methoxy-...)
Affinity DataKd:  1.80E+3nMAssay Description:Average Binding Constant for EPHA3; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEphrin type-A receptor 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 16673BDBM16673(BAY439006 | CHEMBL1336 | BAY 43-9006 | 4-[4-({[4-c...)
Affinity DataKd:  1.90E+3nMAssay Description:Binding constant for EPHA3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetEphrin type-A receptor 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 16673BDBM16673(BAY439006 | CHEMBL1336 | BAY 43-9006 | 4-[4-({[4-c...)
Affinity DataKd:  1.90E+3nMAssay Description:Binding affinity to EPHA3More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetEphrin type-A receptor 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 16673BDBM16673(BAY439006 | CHEMBL1336 | BAY 43-9006 | 4-[4-({[4-c...)
Affinity DataKd:  1.90E+3nMAssay Description:Binding constant for EPHA3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetEphrin type-A receptor 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21BDBM21(VANDETANIB | N-(4-bromo-2-fluorophenyl)-6-methoxy-...)
Affinity DataKd:  2.00E+3nMAssay Description:Binding constant for EPHA3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetEphrin type-A receptor 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21BDBM21(VANDETANIB | N-(4-bromo-2-fluorophenyl)-6-methoxy-...)
Affinity DataKd:  2.00E+3nMAssay Description:Binding constant for EPHA3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetEphrin type-A receptor 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 4814BDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataKd:  2.10E+3nMAssay Description:Binding constant for EPHA3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetEphrin type-A receptor 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 4779BDBM4779(cid_156414 | PD0183805 | CHEMBL545315 | CHEMBL3196...)
Affinity DataKd:  2.10E+3nMAssay Description:Binding constant for EPHA3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetEphrin type-A receptor 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 31093BDBM31093(cid_11712649 | 4-[[7-[2,6-bis(fluoranyl)phenyl]-9-...)
Affinity DataKd:  2.10E+3nMAssay Description:Binding constant for EPHA3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetEphrin type-A receptor 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 31093BDBM31093(cid_11712649 | 4-[[7-[2,6-bis(fluoranyl)phenyl]-9-...)
Affinity DataKd:  2.10E+3nMAssay Description:Binding constant for EPHA3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetEphrin type-A receptor 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 4779BDBM4779(cid_156414 | PD0183805 | CHEMBL545315 | CHEMBL3196...)
Affinity DataKd:  2.10E+3nMAssay Description:Binding constant for EPHA3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetEphrin type-A receptor 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 4814BDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataKd:  2.10E+3nMAssay Description:Binding constant for EPHA3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetEphrin type-A receptor 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 4814BDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataKd:  2.10E+3nMAssay Description:Binding affinity to EPHA3More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetEphrin type-A receptor 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 31095BDBM31095(5-[(Z)-(5-fluoranyl-2-oxidanylidene-1H-indol-3-yli...)
Affinity DataKd:  2.30E+3nMAssay Description:Binding constant for EPHA3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetEphrin type-A receptor 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 5446BDBM5446(Erlotinib | OSI-774 | N-(3-ethynylphenyl)-6,7-bis(...)
Affinity DataKd:  2.40E+3nMAssay Description:Binding constant for EPHA3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetEphrin type-A receptor 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 5446BDBM5446(Erlotinib | OSI-774 | N-(3-ethynylphenyl)-6,7-bis(...)
Affinity DataKd:  2.40E+3nMAssay Description:Binding constant for EPHA3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetEphrin type-A receptor 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50355495BDBM50355495(CHEMBL1908391)
Affinity DataKd:  2.50E+3nMAssay Description:Binding constant for EPHA3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetEphrin type-A receptor 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248614BDBM50248614(CHEMBL4066819)
Affinity DataKd: >3.00E+3nMAssay Description:Binding affinity to partial length wild-type human EPHA3 (D604 to K889 residues) expressed in bacterial expression system by kinome scan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details Article
PubMed
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