Compile Data Set for Download or QSAR
Report error Found 861 of ic50 for UniProtKB: P14061
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Elexopharm

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50525969BDBM50525969(CHEMBL4529443)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of human placental cytosolic fraction 17beta-HSD1 using [3H]-E1 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Elexopharm

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50525968BDBM50525968(CHEMBL4457145)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of human placental cytosolic fraction 17beta-HSD1 using [3H]-E1 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Elexopharm

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50232174BDBM50232174(CHEMBL4063985)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of human placental cytosolic 17beta-HSD1 assessed as reduction in activation of [2,4,6,7-3H]-E1 substrate to E2 after 10 mins in presence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2019
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Elexopharm

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50232109BDBM50232109(CHEMBL4103524)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human placental cytosolic 17beta-HSD1 assessed as reduction in activation of [2,4,6,7-3H]-E1 substrate to E2 after 10 mins in presence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2019
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Elexopharm

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50466018BDBM50466018(CHEMBL4283851)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human placental cytosolic 17beta-HSD1 using [3H]-E1 as substrate after 10 mins in presence of NADPH by radio-flow detector based analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Elexopharm

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50232150BDBM50232150(CHEMBL4101264)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human placental cytosolic 17beta-HSD1 assessed as reduction in activation of [2,4,6,7-3H]-E1 substrate to E2 after 10 mins in presence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2019
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Elexopharm

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50232150BDBM50232150(CHEMBL4101264)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human placental cytosolic fraction 17beta-HSD1 using [3H]-E1 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Elexopharm

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50232169BDBM50232169(CHEMBL4063839)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human placental cytosolic 17beta-HSD1 assessed as reduction in activation of [2,4,6,7-3H]-E1 substrate to E2 after 10 mins in presence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2019
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Elexopharm

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50232163BDBM50232163(CHEMBL4079675)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human placental cytosolic 17beta-HSD1 assessed as reduction in activation of [2,4,6,7-3H]-E1 substrate to E2 after 10 mins in presence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2019
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Elexopharm

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50232163BDBM50232163(CHEMBL4079675)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human placental cytosolic fraction 17beta-HSD1 using [3H]-E1 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Elexopharm

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50516202BDBM50516202(CHEMBL4454887)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human placental cytosolic fraction 17beta-HSD1 using [3H]-E1 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Elexopharm

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50515441BDBM50515441(CHEMBL4466918)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of human placental cytosolic fraction 17beta-HSD1 using [3H]-E1 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Elexopharm

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50525964BDBM50525964(CHEMBL4546082)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of human placental cytosolic fraction 17beta-HSD1 using [3H]-E1 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Elexopharm

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50525962BDBM50525962(CHEMBL4464314)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human placental cytosolic fraction 17beta-HSD1 using [3H]-E1 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Elexopharm

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50232177BDBM50232177(CHEMBL4077264)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of human placental cytosolic 17beta-HSD1 assessed as reduction in activation of [2,4,6,7-3H]-E1 substrate to E2 after 10 mins in presence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2019
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Elexopharm

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50466019BDBM50466019(CHEMBL4286251)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of human placental cytosolic fraction 17beta-HSD1 using [3H]-E1 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Elexopharm

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50466019BDBM50466019(CHEMBL4286251)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of human placental cytosolic 17beta-HSD1 using [3H]-E1 as substrate after 10 mins in presence of NADPH by radio-flow detector based analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Elexopharm

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266402BDBM50266402(CHEMBL4071245)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human placental cytosolic 17beta-HSD1 using [3H]-E1/E1 substrate and NADH after 10 mins by HPLC based radio-detection methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2020
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Elexopharm

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266402BDBM50266402(CHEMBL4071245)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human placental cytosolic fraction 17beta-HSD1 using [3H]E1 as substrate measured after 10 mins in presence of NADH by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Elexopharm

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50515446BDBM50515446(CHEMBL4441152)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human placental cytosolic fraction 17beta-HSD1 using [3H]-E1 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Elexopharm

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50515446BDBM50515446(CHEMBL4441152)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human placental cytosolic fraction 17beta-HSD1 using [3H]-E1 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Elexopharm

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50466008BDBM50466008(CHEMBL4290218)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human placental cytosolic 17beta-HSD1 using [3H]-E1 as substrate after 10 mins in presence of NADPH by radio-flow detector based analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Elexopharm

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50232151BDBM50232151(CHEMBL4099360)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human placental cytosolic 17beta-HSD1 assessed as reduction in activation of [2,4,6,7-3H]-E1 substrate to E2 after 10 mins in presence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2019
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Elexopharm

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50232147BDBM50232147(CHEMBL4062959)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human placental cytosolic 17beta-HSD1 assessed as reduction in activation of [2,4,6,7-3H]-E1 substrate to E2 after 10 mins in presence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2019
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Elexopharm

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266400BDBM50266400(CHEMBL4072794)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human placental cytosolic 17beta-HSD1 using [3H]-E1/E1 substrate and NADH after 10 mins by HPLC based radio-detection methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2020
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Elexopharm

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50525963BDBM50525963(CHEMBL4582194)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human placental cytosolic fraction 17beta-HSD1 using [3H]-E1 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Elexopharm

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50232158BDBM50232158(CHEMBL4062685)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human placental cytosolic 17beta-HSD1 assessed as reduction in activation of [2,4,6,7-3H]-E1 substrate to E2 after 10 mins in presence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2019
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Elexopharm

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50466012BDBM50466012(CHEMBL4287575)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human placental cytosolic 17beta-HSD1 using [3H]-E1 as substrate after 10 mins in presence of NADPH by radio-flow detector based analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Elexopharm

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50466012BDBM50466012(CHEMBL4287575)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human placental cytosolic fraction 17beta-HSD1 using [3H]-E1 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Elexopharm

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50466030BDBM50466030(CHEMBL4291714)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human placental cytosolic 17beta-HSD1 using [3H]-E1 as substrate after 10 mins in presence of NADPH by radio-flow detector based analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Elexopharm

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50525967BDBM50525967(CHEMBL4538007)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human placental cytosolic fraction 17beta-HSD1 using [3H]-E1 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Elexopharm

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50515433BDBM50515433(CHEMBL4585585)
Affinity DataIC50: 2nMAssay Description:Inhibition of human placental cytosolic fraction 17beta-HSD1 using [3H]-E1 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Elexopharm

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126971BDBM50126971(CHEMBL3629585)
Affinity DataIC50: 2nMAssay Description:Inhibition of human placental cytosolic 17beta HSD1 using unlabeled- and labelled [2,4,6,7-3H]-E1 as substrate incubated for 10 mins by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Elexopharm

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126973BDBM50126973(CHEMBL3629587)
Affinity DataIC50: 2nMAssay Description:Inhibition of human placental cytosolic 17beta HSD1 using unlabeled- and labelled [2,4,6,7-3H]-E1 as substrate incubated for 10 mins by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Elexopharm

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126976BDBM50126976(CHEMBL3629590)
Affinity DataIC50: 2nMAssay Description:Inhibition of human placental cytosolic 17beta HSD1 using unlabeled- and labelled [2,4,6,7-3H]-E1 as substrate incubated for 10 mins by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Elexopharm

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50232162BDBM50232162(CHEMBL4082298)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human placental cytosolic 17beta-HSD1 assessed as reduction in activation of [2,4,6,7-3H]-E1 substrate to E2 after 10 mins in presence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2019
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Elexopharm

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50232175BDBM50232175(CHEMBL4060257)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human placental cytosolic 17beta-HSD1 assessed as reduction in activation of [2,4,6,7-3H]-E1 substrate to E2 after 10 mins in presence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2019
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Elexopharm

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50174298BDBM50174298(3-(4-(3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl)bicy...)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Elexopharm

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266423BDBM50266423(CHEMBL4078356)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of human placental cytosolic 17beta-HSD1 using [3H]-E1/E1 substrate and NADH after 10 mins by HPLC based radio-detection methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2020
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Elexopharm

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50515443BDBM50515443(CHEMBL4443578)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human placental cytosolic fraction 17beta-HSD1 using [3H]-E1 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Elexopharm

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50232176BDBM50232176(CHEMBL4091749)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human placental cytosolic 17beta-HSD1 assessed as reduction in activation of [2,4,6,7-3H]-E1 substrate to E2 after 10 mins in presence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2019
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Elexopharm

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50525970BDBM50525970(CHEMBL4450585)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human placental cytosolic fraction 17beta-HSD1 using [3H]-E1 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Elexopharm

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266404BDBM50266404(CHEMBL4102153)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human placental cytosolic 17beta-HSD1 using [3H]-E1/E1 substrate and NADH after 10 mins by HPLC based radio-detection methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2020
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Elexopharm

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50587607BDBM50587607(CHEMBL5089787)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of human placental cytosolic fraction 17beta-HSD1 using [3H]-E1 as substrate in presence of NADH measured after 10 mins by HPLC methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Elexopharm

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266422BDBM50266422(CHEMBL4099681)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of human placental cytosolic 17beta-HSD1 using [3H]-E1/E1 substrate and NADH after 10 mins by HPLC based radio-detection methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2020
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Elexopharm

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50587607BDBM50587607(CHEMBL5089787)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of human placental cytosolic fraction 17beta-HSD1 using [3H]-E1 as substrate in presence of NADH measured after 10 mins by HPLC methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Elexopharm

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50587609BDBM50587609(CHEMBL5090458)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of human placental cytosolic fraction 17beta-HSD1 using [3H]-E1 as substrate in presence of NADH measured after 10 mins by HPLC methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Elexopharm

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50587601BDBM50587601(CHEMBL5080299)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of human 17beta-HSD1 expressed in human T47D cells using [3H]E1 as substrate incubated for 1 hr followed by substrate addition measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Elexopharm

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50232166BDBM50232166(CHEMBL4071588)
Affinity DataIC50: 3nMAssay Description:Inhibition of human placental cytosolic 17beta-HSD1 assessed as reduction in activation of [2,4,6,7-3H]-E1 substrate to E2 after 10 mins in presence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2019
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Elexopharm

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126972BDBM50126972(CHEMBL3629586)
Affinity DataIC50: 3nMAssay Description:Inhibition of human placental cytosolic 17beta HSD1 using unlabeled- and labelled [2,4,6,7-3H]-E1 as substrate incubated for 10 mins by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
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