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Found 1268 of ic50 for UniProtKB: P80457
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Kissei Pharmaceutical

US Patent
LigandPNGBDBM158057(US9023882, 356)
Affinity DataIC50:  1.70nMT: 2°CAssay Description:Xanthine oxidase (from bovine milk, Sigma) was prepared with phosphate-buffered saline (PBS) at 0.02 units/mL, and then the solution was added to 96 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Kissei Pharmaceutical

US Patent
LigandPNGBDBM157887(US9023882, 160)
Affinity DataIC50:  2.10nMT: 2°CAssay Description:Xanthine oxidase (from bovine milk, Sigma) was prepared with phosphate-buffered saline (PBS) at 0.02 units/mL, and then the solution was added to 96 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Kissei Pharmaceutical

US Patent
LigandPNGBDBM157874(US9023882, 147)
Affinity DataIC50:  2.10nMT: 2°CAssay Description:Xanthine oxidase (from bovine milk, Sigma) was prepared with phosphate-buffered saline (PBS) at 0.02 units/mL, and then the solution was added to 96 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Kissei Pharmaceutical

US Patent
LigandPNGBDBM121552(US8729273, 22)
Affinity DataIC50:  2.10nMAssay Description:Xanthine oxidase originated from bovine milk was incubated for 3 min with test compounds, and the initial velocity of uric acid formation was determi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Kissei Pharmaceutical

US Patent
LigandPNGBDBM157944(US9023882, 233)
Affinity DataIC50:  2.30nMT: 2°CAssay Description:Xanthine oxidase (from bovine milk, Sigma) was prepared with phosphate-buffered saline (PBS) at 0.02 units/mL, and then the solution was added to 96 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Kissei Pharmaceutical

US Patent
LigandPNGBDBM50098066(1-(3-Cyano-4-hydroxy-phenyl)-1H-pyrazole-4-carboxy...)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of bovine milk xanthine oxidoreductase pre-incubated for 3 mins followed xanthine substrate addition and measured every 1 mins for 10 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Kissei Pharmaceutical

US Patent
LigandPNGBDBM158072(US9023882, 371)
Affinity DataIC50:  2.40nMT: 2°CAssay Description:Xanthine oxidase (from bovine milk, Sigma) was prepared with phosphate-buffered saline (PBS) at 0.02 units/mL, and then the solution was added to 96 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Kissei Pharmaceutical

US Patent
LigandPNGBDBM157880(US9023882, 153)
Affinity DataIC50:  2.40nMT: 2°CAssay Description:Xanthine oxidase (from bovine milk, Sigma) was prepared with phosphate-buffered saline (PBS) at 0.02 units/mL, and then the solution was added to 96 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Kissei Pharmaceutical

US Patent
LigandPNGBDBM157875(US9023882, 148)
Affinity DataIC50:  2.5nMT: 2°CAssay Description:Xanthine oxidase (from bovine milk, Sigma) was prepared with phosphate-buffered saline (PBS) at 0.02 units/mL, and then the solution was added to 96 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Kissei Pharmaceutical

US Patent
LigandPNGBDBM157886(US9023882, 159)
Affinity DataIC50:  2.70nMT: 2°CAssay Description:Xanthine oxidase (from bovine milk, Sigma) was prepared with phosphate-buffered saline (PBS) at 0.02 units/mL, and then the solution was added to 96 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Kissei Pharmaceutical

US Patent
LigandPNGBDBM157954(US9023882, 245)
Affinity DataIC50:  2.80nMT: 2°CAssay Description:Xanthine oxidase (from bovine milk, Sigma) was prepared with phosphate-buffered saline (PBS) at 0.02 units/mL, and then the solution was added to 96 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Kissei Pharmaceutical

US Patent
LigandPNGBDBM121532(US8729273, 2)
Affinity DataIC50:  2.80nMAssay Description:Xanthine oxidase originated from bovine milk was incubated for 3 min with test compounds, and the initial velocity of uric acid formation was determi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Kissei Pharmaceutical

US Patent
LigandPNGBDBM50127486(CHEMBL3628190)
Affinity DataIC50:  3nMAssay Description:Inhibition of bovine XO using xanthine as substrate after 120 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Kissei Pharmaceutical

US Patent
LigandPNGBDBM50127441(CHEMBL3628191)
Affinity DataIC50:  3nMAssay Description:Inhibition of bovine XO using xanthine as substrate after 120 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Kissei Pharmaceutical

US Patent
LigandPNGBDBM50320491(2-(3-CYANO-4-ISOBUTOXY-PHENYL)-4-METHYL-5-THIAZOLE...)
Affinity DataIC50:  3nMAssay Description:Inhibition of bovine xanthine oxidase by spectrophotometryMore data for this Ligand-Target Pair
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Kissei Pharmaceutical

US Patent
LigandPNGBDBM157970(US9023882, 262)
Affinity DataIC50:  3.10nMT: 2°CAssay Description:Xanthine oxidase (from bovine milk, Sigma) was prepared with phosphate-buffered saline (PBS) at 0.02 units/mL, and then the solution was added to 96 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Kissei Pharmaceutical

US Patent
LigandPNGBDBM50127441(CHEMBL3628191)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of bovine XO using xanthine as substrate after 120 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Kissei Pharmaceutical

US Patent
LigandPNGBDBM158054(US9023882, 352)
Affinity DataIC50:  3.20nMT: 2°CAssay Description:Xanthine oxidase (from bovine milk, Sigma) was prepared with phosphate-buffered saline (PBS) at 0.02 units/mL, and then the solution was added to 96 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Kissei Pharmaceutical

US Patent
LigandPNGBDBM50127486(CHEMBL3628190)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of bovine XO using xanthine as substrate after 120 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Kissei Pharmaceutical

US Patent
LigandPNGBDBM50311264(4-(3-(4-methoxy-3-nitrophenyl)-1H-1,2,4-triazol-5-...)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of bovine milk XOR-mediated uric acid formation after 15 mins by spectrophotometerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Kissei Pharmaceutical

US Patent
LigandPNGBDBM157950(US9023882, 240)
Affinity DataIC50:  3.30nMT: 2°CAssay Description:Xanthine oxidase (from bovine milk, Sigma) was prepared with phosphate-buffered saline (PBS) at 0.02 units/mL, and then the solution was added to 96 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Kissei Pharmaceutical

US Patent
LigandPNGBDBM158056(US9023882, 355)
Affinity DataIC50:  3.30nMT: 2°CAssay Description:Xanthine oxidase (from bovine milk, Sigma) was prepared with phosphate-buffered saline (PBS) at 0.02 units/mL, and then the solution was added to 96 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Kissei Pharmaceutical

US Patent
LigandPNGBDBM121531(US8729273, 1)
Affinity DataIC50:  3.40nMAssay Description:Xanthine oxidase originated from bovine milk was incubated for 3 min with test compounds, and the initial velocity of uric acid formation was determi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Kissei Pharmaceutical

US Patent
LigandPNGBDBM50098068(1-[3-CYANO-4-(NEOPENTYLOXY)PHENYL]-1H-PYRAZOLE-4-C...)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of bovine milk xanthine oxidoreductase pre-incubated for 3 mins followed xanthine substrate addition and measured every 1 mins for 10 mins...More data for this Ligand-Target Pair
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Kissei Pharmaceutical

US Patent
LigandPNGBDBM157948(US9023882, 238)
Affinity DataIC50:  3.60nMT: 2°CAssay Description:Xanthine oxidase (from bovine milk, Sigma) was prepared with phosphate-buffered saline (PBS) at 0.02 units/mL, and then the solution was added to 96 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Kissei Pharmaceutical

US Patent
LigandPNGBDBM157951(US9023882, 241)
Affinity DataIC50:  3.60nMT: 2°CAssay Description:Xanthine oxidase (from bovine milk, Sigma) was prepared with phosphate-buffered saline (PBS) at 0.02 units/mL, and then the solution was added to 96 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Kissei Pharmaceutical

US Patent
LigandPNGBDBM157953(US9023882, 244)
Affinity DataIC50:  3.60nMT: 2°CAssay Description:Xanthine oxidase (from bovine milk, Sigma) was prepared with phosphate-buffered saline (PBS) at 0.02 units/mL, and then the solution was added to 96 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Kissei Pharmaceutical

US Patent
LigandPNGBDBM157938(US9023882, 227)
Affinity DataIC50:  3.60nMT: 2°CAssay Description:Xanthine oxidase (from bovine milk, Sigma) was prepared with phosphate-buffered saline (PBS) at 0.02 units/mL, and then the solution was added to 96 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Kissei Pharmaceutical

US Patent
LigandPNGBDBM50254496(4-(3-(4-isobutoxy-3-nitrophenyl)-1H-1,2,4-triazol-...)
Affinity DataIC50:  3.70nMAssay Description:Inhibition of bovine milk XOR-mediated uric acid formation after 15 mins by spectrophotometerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Kissei Pharmaceutical

US Patent
LigandPNGBDBM121536(US8729273, 6)
Affinity DataIC50:  3.80nMAssay Description:Xanthine oxidase originated from bovine milk was incubated for 3 min with test compounds, and the initial velocity of uric acid formation was determi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Kissei Pharmaceutical

US Patent
LigandPNGBDBM157921(US9023882, 207)
Affinity DataIC50:  3.80nMT: 2°CAssay Description:Xanthine oxidase (from bovine milk, Sigma) was prepared with phosphate-buffered saline (PBS) at 0.02 units/mL, and then the solution was added to 96 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Kissei Pharmaceutical

US Patent
LigandPNGBDBM153045(US8993616, 191)
Affinity DataIC50:  3.90nMT: 2°CAssay Description:Test compounds were dissolved in DMSO (Wako) at 40 mM concentration and then diluted to intended concentrations with phosphate-buffered saline (PBS)....More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Kissei Pharmaceutical

US Patent
LigandPNGBDBM157992(US9023882, 285)
Affinity DataIC50:  3.90nMT: 2°CAssay Description:Xanthine oxidase (from bovine milk, Sigma) was prepared with phosphate-buffered saline (PBS) at 0.02 units/mL, and then the solution was added to 96 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Kissei Pharmaceutical

US Patent
LigandPNGBDBM157967(US9023882, 258)
Affinity DataIC50:  3.90nMT: 2°CAssay Description:Xanthine oxidase (from bovine milk, Sigma) was prepared with phosphate-buffered saline (PBS) at 0.02 units/mL, and then the solution was added to 96 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Kissei Pharmaceutical

US Patent
LigandPNGBDBM157879(US9023882, 152)
Affinity DataIC50:  4nMT: 2°CAssay Description:Xanthine oxidase (from bovine milk, Sigma) was prepared with phosphate-buffered saline (PBS) at 0.02 units/mL, and then the solution was added to 96 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Kissei Pharmaceutical

US Patent
LigandPNGBDBM50240899(5,7-Dihydroxy-2-(4-hydroxy-phenyl)-3-methoxy-chrom...)
Affinity DataIC50:  4nMAssay Description:Inhibition of bovine milk xanthine oxidase using xanthine as substrate preincubated for 15 mins followed by substrate addition measured after 30 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Kissei Pharmaceutical

US Patent
LigandPNGBDBM158040(US9023882, 337)
Affinity DataIC50:  4nMT: 2°CAssay Description:Xanthine oxidase (from bovine milk, Sigma) was prepared with phosphate-buffered saline (PBS) at 0.02 units/mL, and then the solution was added to 96 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Kissei Pharmaceutical

US Patent
LigandPNGBDBM157873(US9023882, 146)
Affinity DataIC50:  4nMT: 2°CAssay Description:Xanthine oxidase (from bovine milk, Sigma) was prepared with phosphate-buffered saline (PBS) at 0.02 units/mL, and then the solution was added to 96 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Kissei Pharmaceutical

US Patent
LigandPNGBDBM50426742(CHEMBL2322167)
Affinity DataIC50:  4nMAssay Description:Inhibition of bovine xanthine oxidase-mediated uric acid production after 30 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Kissei Pharmaceutical

US Patent
LigandPNGBDBM157945(US9023882, 234)
Affinity DataIC50:  4nMT: 2°CAssay Description:Xanthine oxidase (from bovine milk, Sigma) was prepared with phosphate-buffered saline (PBS) at 0.02 units/mL, and then the solution was added to 96 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Kissei Pharmaceutical

US Patent
LigandPNGBDBM157881(US9023882, 154)
Affinity DataIC50:  4nMT: 2°CAssay Description:Xanthine oxidase (from bovine milk, Sigma) was prepared with phosphate-buffered saline (PBS) at 0.02 units/mL, and then the solution was added to 96 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Kissei Pharmaceutical

US Patent
LigandPNGBDBM157966(US9023882, 257)
Affinity DataIC50:  4.10nMT: 2°CAssay Description:Xanthine oxidase (from bovine milk, Sigma) was prepared with phosphate-buffered saline (PBS) at 0.02 units/mL, and then the solution was added to 96 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Kissei Pharmaceutical

US Patent
LigandPNGBDBM50457198(CHEMBL4203776)
Affinity DataIC50:  4.20nMAssay Description:Inhibition of bovine milk xanthine oxidoreductase pre-incubated for 3 mins followed xanthine substrate addition and measured every 1 mins for 10 mins...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Kissei Pharmaceutical

US Patent
LigandPNGBDBM153046(US8993616, 192)
Affinity DataIC50:  4.30nMT: 2°CAssay Description:Test compounds were dissolved in DMSO (Wako) at 40 mM concentration and then diluted to intended concentrations with phosphate-buffered saline (PBS)....More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Kissei Pharmaceutical

US Patent
LigandPNGBDBM158042(US9023882, 339)
Affinity DataIC50:  4.40nMT: 2°CAssay Description:Xanthine oxidase (from bovine milk, Sigma) was prepared with phosphate-buffered saline (PBS) at 0.02 units/mL, and then the solution was added to 96 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Kissei Pharmaceutical

US Patent
LigandPNGBDBM121534(US8729273, 4)
Affinity DataIC50:  4.5nMAssay Description:Xanthine oxidase originated from bovine milk was incubated for 3 min with test compounds, and the initial velocity of uric acid formation was determi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Kissei Pharmaceutical

US Patent
LigandPNGBDBM157939(US9023882, 228)
Affinity DataIC50:  4.60nMT: 2°CAssay Description:Xanthine oxidase (from bovine milk, Sigma) was prepared with phosphate-buffered saline (PBS) at 0.02 units/mL, and then the solution was added to 96 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Kissei Pharmaceutical

US Patent
LigandPNGBDBM157925(US9023882, 211)
Affinity DataIC50:  4.60nMT: 2°CAssay Description:Xanthine oxidase (from bovine milk, Sigma) was prepared with phosphate-buffered saline (PBS) at 0.02 units/mL, and then the solution was added to 96 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Kissei Pharmaceutical

US Patent
LigandPNGBDBM121547(US8729273, 17)
Affinity DataIC50:  4.60nMAssay Description:Xanthine oxidase originated from bovine milk was incubated for 3 min with test compounds, and the initial velocity of uric acid formation was determi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Kissei Pharmaceutical

US Patent
LigandPNGBDBM121539(US8729273, 9)
Affinity DataIC50:  4.60nMAssay Description:Xanthine oxidase originated from bovine milk was incubated for 3 min with test compounds, and the initial velocity of uric acid formation was determi...More data for this Ligand-Target Pair
In DepthDetails US Patent
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