Compile Data Set for Download or QSAR
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Found 15 of ki for UniProtKB: B0B3F0
TargetGenome polyprotein(Hepatitis C virus)
Janssen Ireland

US Patent
LigandPNGBDBM123410(US8741926, 82 | US8754106, 82 | US8754106, 91)
Affinity DataKi:  0.0500nMAssay Description:The aim of this in vitro assay was to measure the inhibition of HCV NS3/4A protease complexes by the compounds of the present invention. This assay p...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus)
Janssen Ireland

US Patent
LigandPNGBDBM123415(US8741926, 95 | US8754106, 95)
Affinity DataKi:  0.100nMAssay Description:The aim of this in vitro assay was to measure the inhibition of HCV NS3/4A protease complexes by the compounds of the present invention. This assay p...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus)
Janssen Ireland

US Patent
LigandPNGBDBM123413(US8741926, 94 | US8754106, 94)
Affinity DataKi:  0.100nMAssay Description:The aim of this in vitro assay was to measure the inhibition of HCV NS3/4A protease complexes by the compounds of the present invention. This assay p...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus)
Janssen Ireland

US Patent
LigandPNGBDBM124106(US8754106, 56)
Affinity DataKi:  0.100nMAssay Description:The aim of this in vitro assay was to measure the inhibition of HCV NS3/4A protease complexes by the compounds of the present invention. This assay p...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus)
Janssen Ireland

US Patent
LigandPNGBDBM124107(US8754105, 23)
Affinity DataKi:  0.200nM ΔG°:  -13.4kcal/molepH: 7.5 T: 2°CAssay Description:The aim of this in vitro assay was to measure the inhibition of HCV NS3/4A protease complexes by the compounds of the present invention. This assay p...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus)
Janssen Ireland

US Patent
LigandPNGBDBM123414(US8741926, 48 | US8754106, 48)
Affinity DataKi:  0.25nMAssay Description:The aim of this in vitro assay was to measure the inhibition of HCV NS3/4A protease complexes by the compounds of the present invention. This assay p...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus)
Janssen Ireland

US Patent
LigandPNGBDBM123412(US8741926, 57 | US8754106, 57)
Affinity DataKi:  0.300nMAssay Description:The aim of this in vitro assay was to measure the inhibition of HCV NS3/4A protease complexes by the compounds of the present invention. This assay p...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus)
Janssen Ireland

US Patent
LigandPNGBDBM50336504((2R,3aR,10Z,11aS,12aR,14aR)-N-(cyclopropylsulfonyl...)
Affinity DataKi:  0.5nMAssay Description:The aim of this in vitro assay was to measure the inhibition of HCV NS3/4A protease complexes by the compounds of the present invention. This assay p...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus)
Janssen Ireland

US Patent
LigandPNGBDBM124112(US8754105, 25)
Affinity DataKi:  2.40nM ΔG°:  -11.9kcal/molepH: 7.5 T: 2°CAssay Description:The aim of this in vitro assay was to measure the inhibition of HCV NS3/4A protease complexes by the compounds of the present invention. This assay p...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus)
Janssen Ireland

US Patent
LigandPNGBDBM124105(US8754106, 55)
Affinity DataKi:  5nMAssay Description:The aim of this in vitro assay was to measure the inhibition of HCV NS3/4A protease complexes by the compounds of the present invention. This assay p...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus)
Janssen Ireland

US Patent
LigandPNGBDBM123410(US8741926, 82 | US8754106, 82 | US8754106, 91)
Affinity DataKi:  9.40nMAssay Description:The aim of this in vitro assay was to measure the inhibition of HCV NS3/4A protease complexes by the compounds of the present invention. This assay p...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus)
Janssen Ireland

US Patent
LigandPNGBDBM124111(US8754105, 24)
Affinity DataKi:  40nM ΔG°:  -10.3kcal/molepH: 7.5 T: 2°CAssay Description:The aim of this in vitro assay was to measure the inhibition of HCV NS3/4A protease complexes by the compounds of the present invention. This assay p...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus)
Janssen Ireland

US Patent
LigandPNGBDBM124110(US8754105, 17)
Affinity DataKi:  43nM ΔG°:  -10.2kcal/molepH: 7.5 T: 2°CAssay Description:The aim of this in vitro assay was to measure the inhibition of HCV NS3/4A protease complexes by the compounds of the present invention. This assay p...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus)
Janssen Ireland

US Patent
LigandPNGBDBM124109(US8754105, 16)
Affinity DataKi:  1.00E+3nM ΔG°:  -8.32kcal/molepH: 7.5 T: 2°CAssay Description:The aim of this in vitro assay was to measure the inhibition of HCV NS3/4A protease complexes by the compounds of the present invention. This assay p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus)
Janssen Ireland

US Patent
LigandPNGBDBM124108(US8754105, 22)
Affinity DataKi:  1.07E+3nM ΔG°:  -8.28kcal/molepH: 7.5 T: 2°CAssay Description:The aim of this in vitro assay was to measure the inhibition of HCV NS3/4A protease complexes by the compounds of the present invention. This assay p...More data for this Ligand-Target Pair
In DepthDetails US Patent