Compile Data Set for Download or QSAR
maximum 50k data
Found 336 of ic50 data for polymerid = 645
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Navire Pharma

US Patent
LigandPNGBDBM488484(US10954243, Example 15)
Affinity DataIC50:  1nMAssay Description:Phosphatase activity of full length wild-type PTPN11(PTPN11-WT) or PTPN11-E76K mutant enzyme was measured using the fluorogenic 6,8-difluoro-4-methyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Navire Pharma

US Patent
LigandPNGBDBM384120(1-(3-(2,3- Dichlorophenyl)-1H- pyrazolo[3,4-b]- py...)
Affinity DataIC50:  2nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Navire Pharma

US Patent
LigandPNGBDBM384120(1-(3-(2,3- Dichlorophenyl)-1H- pyrazolo[3,4-b]- py...)
Affinity DataIC50:  2nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Navire Pharma

US Patent
LigandPNGBDBM384120(1-(3-(2,3- Dichlorophenyl)-1H- pyrazolo[3,4-b]- py...)
Affinity DataIC50:  2nMAssay Description:Phosphatase activity of full length wild-type PTPN11(PTPN11-WT) or PTPN11-E76K mutant enzyme was measured using the fluorogenic 6,8-difluoro-4-methyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Navire Pharma

US Patent
LigandPNGBDBM516932(US11104675, Example 18a | US11104675, Example 18b)
Affinity DataIC50:  3nMAssay Description:Phosphatase activity of full length wild-type PTPN11(PTPN11-WT) or PTPN11-E76K mutant enzyme was measured using the fluorogenic 6,8-difluoro-4-methyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Navire Pharma

US Patent
LigandPNGBDBM488489(US10954243, Example 20)
Affinity DataIC50:  3nMAssay Description:Phosphatase activity of full length wild-type PTPN11(PTPN11-WT) or PTPN11-E76K mutant enzyme was measured using the fluorogenic 6,8-difluoro-4-methyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Navire Pharma

US Patent
LigandPNGBDBM488485(US10954243, Example 16)
Affinity DataIC50:  4nMAssay Description:Phosphatase activity of full length wild-type PTPN11(PTPN11-WT) or PTPN11-E76K mutant enzyme was measured using the fluorogenic 6,8-difluoro-4-methyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Navire Pharma

US Patent
LigandPNGBDBM516935(US11104675, Example 20b)
Affinity DataIC50:  5nMAssay Description:Phosphatase activity of full length wild-type PTPN11(PTPN11-WT) or PTPN11-E76K mutant enzyme was measured using the fluorogenic 6,8-difluoro-4-methyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Navire Pharma

US Patent
LigandPNGBDBM488486(US10954243, Example 17)
Affinity DataIC50:  6nMAssay Description:Phosphatase activity of full length wild-type PTPN11(PTPN11-WT) or PTPN11-E76K mutant enzyme was measured using the fluorogenic 6,8-difluoro-4-methyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Navire Pharma

US Patent
LigandPNGBDBM488488(US10954243, Example 19)
Affinity DataIC50:  6nMAssay Description:Phosphatase activity of full length wild-type PTPN11(PTPN11-WT) or PTPN11-E76K mutant enzyme was measured using the fluorogenic 6,8-difluoro-4-methyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Navire Pharma

US Patent
LigandPNGBDBM488487(US10954243, Example 18)
Affinity DataIC50:  9nMAssay Description:Phosphatase activity of full length wild-type PTPN11(PTPN11-WT) or PTPN11-E76K mutant enzyme was measured using the fluorogenic 6,8-difluoro-4-methyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Navire Pharma

US Patent
LigandPNGBDBM516934(US11104675, Example 19b)
Affinity DataIC50:  12nMAssay Description:Phosphatase activity of full length wild-type PTPN11(PTPN11-WT) or PTPN11-E76K mutant enzyme was measured using the fluorogenic 6,8-difluoro-4-methyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Navire Pharma

US Patent
LigandPNGBDBM488480(US10954243, Example 11)
Affinity DataIC50:  17nMAssay Description:Phosphatase activity of full length wild-type PTPN11(PTPN11-WT) or PTPN11-E76K mutant enzyme was measured using the fluorogenic 6,8-difluoro-4-methyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Navire Pharma

US Patent
LigandPNGBDBM488476(US10954243, Example 7)
Affinity DataIC50:  19nMAssay Description:Phosphatase activity of full length wild-type PTPN11(PTPN11-WT) or PTPN11-E76K mutant enzyme was measured using the fluorogenic 6,8-difluoro-4-methyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Navire Pharma

US Patent
LigandPNGBDBM516921(US11104675, Example 12a | US11104675, Example 12b)
Affinity DataIC50:  20nMAssay Description:Phosphatase activity of full length wild-type PTPN11(PTPN11-WT) or PTPN11-E76K mutant enzyme was measured using the fluorogenic 6,8-difluoro-4-methyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Navire Pharma

US Patent
LigandPNGBDBM488483(US10954243, Example 14)
Affinity DataIC50:  22nMAssay Description:Phosphatase activity of full length wild-type PTPN11(PTPN11-WT) or PTPN11-E76K mutant enzyme was measured using the fluorogenic 6,8-difluoro-4-methyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Navire Pharma

US Patent
LigandPNGBDBM497074(US11001561, Compound 63 | US11001561, Compound 63a...)
Affinity DataIC50:  28nMAssay Description:Phosphatase activity of full length wild-type PTPN11(PTPN11-WT) or PTPN11-E76K mutant enzyme was measured using the fluorogenic 6,8-difluoro-4-methyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Navire Pharma

US Patent
LigandPNGBDBM384163((R)-8-(3-(2-chloro-3- methoxyphenyl)-1H- pyrazolo[...)
Affinity DataIC50:  39nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Navire Pharma

US Patent
LigandPNGBDBM384163((R)-8-(3-(2-chloro-3- methoxyphenyl)-1H- pyrazolo[...)
Affinity DataIC50:  39nMAssay Description:Phosphatase activity of full length wild-type PTPN11(PTPN11-WT) or PTPN11-E76K mutant enzyme was measured using the fluorogenic 6,8-difluoro-4-methyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Navire Pharma

US Patent
LigandPNGBDBM384163((R)-8-(3-(2-chloro-3- methoxyphenyl)-1H- pyrazolo[...)
Affinity DataIC50:  39nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Navire Pharma

US Patent
LigandPNGBDBM384191((R)-8-(3-(3-Chloro-2-(methylamino)pyridin-4-yl)-1H...)
Affinity DataIC50:  43nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Navire Pharma

US Patent
LigandPNGBDBM384191((R)-8-(3-(3-Chloro-2-(methylamino)pyridin-4-yl)-1H...)
Affinity DataIC50:  43nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Navire Pharma

US Patent
LigandPNGBDBM384191((R)-8-(3-(3-Chloro-2-(methylamino)pyridin-4-yl)-1H...)
Affinity DataIC50:  43nMAssay Description:Phosphatase activity of full length wild-type PTPN11(PTPN11-WT) or PTPN11-E76K mutant enzyme was measured using the fluorogenic 6,8-difluoro-4-methyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Navire Pharma

US Patent
LigandPNGBDBM516917(US11104675, Example 9)
Affinity DataIC50:  45nMAssay Description:Phosphatase activity of full length wild-type PTPN11(PTPN11-WT) or PTPN11-E76K mutant enzyme was measured using the fluorogenic 6,8-difluoro-4-methyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Navire Pharma

US Patent
LigandPNGBDBM488491((6-((3S,4S)-4- amino-3-methyl-2- oxa-8- azaspiro[4...)
Affinity DataIC50:  48nMAssay Description:Phosphatase activity of full length wild-type PTPN11(PTPN11-WT) or PTPN11-E76K mutant enzyme was measured using the fluorogenic 6,8-difluoro-4-methyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Navire Pharma

US Patent
LigandPNGBDBM488470(US10954243, Example 1)
Affinity DataIC50:  68nMAssay Description:Phosphatase activity of full length wild-type PTPN11(PTPN11-WT) or PTPN11-E76K mutant enzyme was measured using the fluorogenic 6,8-difluoro-4-methyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Navire Pharma

US Patent
LigandPNGBDBM384147((1-(3-(4-Chloro-3-methoxyphenyl)-1H-pyrazolo[3,4-b...)
Affinity DataIC50:  72nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Navire Pharma

US Patent
LigandPNGBDBM384147((1-(3-(4-Chloro-3-methoxyphenyl)-1H-pyrazolo[3,4-b...)
Affinity DataIC50:  72nMAssay Description:Phosphatase activity of full length wild-type PTPN11(PTPN11-WT) or PTPN11-E76K mutant enzyme was measured using the fluorogenic 6,8-difluoro-4-methyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Navire Pharma

US Patent
LigandPNGBDBM384147((1-(3-(4-Chloro-3-methoxyphenyl)-1H-pyrazolo[3,4-b...)
Affinity DataIC50:  72nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Navire Pharma

US Patent
LigandPNGBDBM384206((2S,4R)-4-Amino-8-(3-(2-amino-3-chloropyridin-4-yl...)
Affinity DataIC50:  75nMAssay Description:Phosphatase activity of full length wild-type PTPN11(PTPN11-WT) or PTPN11-E76K mutant enzyme was measured using the fluorogenic 6,8-difluoro-4-methyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Navire Pharma

US Patent
LigandPNGBDBM384152((S)-8-(3-(2,3-Dichlorophenyl)-1H-pyrazolo[3,4-b]py...)
Affinity DataIC50:  75nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Navire Pharma

US Patent
LigandPNGBDBM384206((2S,4R)-4-Amino-8-(3-(2-amino-3-chloropyridin-4-yl...)
Affinity DataIC50:  75nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Navire Pharma

US Patent
LigandPNGBDBM384152((S)-8-(3-(2,3-Dichlorophenyl)-1H-pyrazolo[3,4-b]py...)
Affinity DataIC50:  75nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Navire Pharma

US Patent
LigandPNGBDBM384206((2S,4R)-4-Amino-8-(3-(2-amino-3-chloropyridin-4-yl...)
Affinity DataIC50:  75nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Navire Pharma

US Patent
LigandPNGBDBM384152((S)-8-(3-(2,3-Dichlorophenyl)-1H-pyrazolo[3,4-b]py...)
Affinity DataIC50:  75nMAssay Description:Phosphatase activity of full length wild-type PTPN11(PTPN11-WT) or PTPN11-E76K mutant enzyme was measured using the fluorogenic 6,8-difluoro-4-methyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Navire Pharma

US Patent
LigandPNGBDBM384141((1-(3-(2-chloro-3- methoxy phenyl)-1H- pyrazolo[3,...)
Affinity DataIC50:  80nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Navire Pharma

US Patent
LigandPNGBDBM384141((1-(3-(2-chloro-3- methoxy phenyl)-1H- pyrazolo[3,...)
Affinity DataIC50:  80nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Navire Pharma

US Patent
LigandPNGBDBM384141((1-(3-(2-chloro-3- methoxy phenyl)-1H- pyrazolo[3,...)
Affinity DataIC50:  80nMAssay Description:Phosphatase activity of full length wild-type PTPN11(PTPN11-WT) or PTPN11-E76K mutant enzyme was measured using the fluorogenic 6,8-difluoro-4-methyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Navire Pharma

US Patent
LigandPNGBDBM384207((1R)-8-[3-(2-amino- 3-chloropyridin-4- yl)-1H-pyra...)
Affinity DataIC50:  83nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Navire Pharma

US Patent
LigandPNGBDBM384207((1R)-8-[3-(2-amino- 3-chloropyridin-4- yl)-1H-pyra...)
Affinity DataIC50:  83nMAssay Description:Phosphatase activity of full length wild-type PTPN11(PTPN11-WT) or PTPN11-E76K mutant enzyme was measured using the fluorogenic 6,8-difluoro-4-methyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Navire Pharma

US Patent
LigandPNGBDBM384207((1R)-8-[3-(2-amino- 3-chloropyridin-4- yl)-1H-pyra...)
Affinity DataIC50:  83nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Navire Pharma

US Patent
LigandPNGBDBM384208((1R)-8-[3-(3-amino- 2-chlorophenyl)-1H- pyrazolo[3...)
Affinity DataIC50:  84nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Navire Pharma

US Patent
LigandPNGBDBM384208((1R)-8-[3-(3-amino- 2-chlorophenyl)-1H- pyrazolo[3...)
Affinity DataIC50:  84nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Navire Pharma

US Patent
LigandPNGBDBM384208((1R)-8-[3-(3-amino- 2-chlorophenyl)-1H- pyrazolo[3...)
Affinity DataIC50:  84nMAssay Description:Phosphatase activity of full length wild-type PTPN11(PTPN11-WT) or PTPN11-E76K mutant enzyme was measured using the fluorogenic 6,8-difluoro-4-methyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Navire Pharma

US Patent
LigandPNGBDBM488477(US10954243, Example 8)
Affinity DataIC50:  90nMAssay Description:Phosphatase activity of full length wild-type PTPN11(PTPN11-WT) or PTPN11-E76K mutant enzyme was measured using the fluorogenic 6,8-difluoro-4-methyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Navire Pharma

US Patent
LigandPNGBDBM516929(US11104675, Example 16a | US11104675, Example 16b)
Affinity DataIC50:  92nMAssay Description:Phosphatase activity of full length wild-type PTPN11(PTPN11-WT) or PTPN11-E76K mutant enzyme was measured using the fluorogenic 6,8-difluoro-4-methyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Navire Pharma

US Patent
LigandPNGBDBM475734(8-(3-(2,3-Dichlorophenyl)-1H-pyrazolo[3,4-b]pyrazi...)
Affinity DataIC50:  98nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Navire Pharma

US Patent
LigandPNGBDBM576074(8-(3-(2,3-Dichlorophenyl)-1H-pyrazolo [3,4-b] pyra...)
Affinity DataIC50:  98nMAssay Description:Phosphatase activity of full length wild-type PTPN11(PTPN11-WT) or PTPN11-E76K mutant enzyme was measured using the fluorogenic 6,8-difluoro-4-methyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Navire Pharma

US Patent
LigandPNGBDBM384177(8-(3-(2,3-Dichlorophenyl)-1H-pyrazolo[3,4-b]pyrazi...)
Affinity DataIC50:  98nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Navire Pharma

US Patent
LigandPNGBDBM384184(4-(6-(4-(Aminomethyl)-4-methylpiperidin-1-yl)-1H-p...)
Affinity DataIC50:  99nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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