Compile Data Set for Download or QSAR
maximum 50k data
Found 21 of ec50 data for polymerid = 7501
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM50288363(CHEMBL4173216)
Affinity DataEC50:  0.300nMAssay Description:Inhibition of DRV-resistant protease V32I/L33F/I54M/V82I mutant in HIV1 transfected in 293T cells after 48 hrs by lentiviral vector-based luciferase ...More data for this Ligand-Target Pair
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM13934(Atazanavir | BMS 232632 | CGP 73547 | CHEMBL1163 |...)
Affinity DataEC50:  0.700nMAssay Description:Inhibition of HIV1 NL4-3 protease assessed as decrease in viral replication in human MT2 cells after 4 days by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM50288363(CHEMBL4173216)
Affinity DataEC50:  1.20nMAssay Description:Inhibition of DRV-resistant protease V32I/L33F/I54M/I84V mutant in HIV1 transfected in 293T cells after 48 hrs by lentiviral vector-based luciferase ...More data for this Ligand-Target Pair
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM50455631(CHEMBL4208792)
Affinity DataEC50:  1.80nMAssay Description:Inhibition of HIV1 NL4-3 protease assessed as decrease in viral replication in human MT2 cells after 4 days by luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM50455630(CHEMBL4216648)
Affinity DataEC50:  5.30nMAssay Description:Inhibition of HIV1 NL4-3 protease assessed as decrease in viral replication in human MT2 cells after 4 days by luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM8125((3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-[(2S...)
Affinity DataEC50:  13nMAssay Description:Inhibition of DRV-resistant protease V32I/L33F/I54M/V82I mutant in HIV1 transfected in 293T cells after 48 hrs by lentiviral vector-based luciferase ...More data for this Ligand-Target Pair
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM50288363(CHEMBL4173216)
Affinity DataEC50:  25nMAssay Description:Inhibition of protease L10F/V32I/M46I/I47V/Q58E/I84V mutant in HIV1 A17 infected in human MT4 cells assessed as reduction in virus-induced cytopathic...More data for this Ligand-Target Pair
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM50288359(CHEMBL4164025)
Affinity DataEC50:  61nMAssay Description:Inhibition of protease L10F/V32I/M46I/I47V/Q58E/I84V mutant in HIV1 A17 infected in human MT4 cells assessed as reduction in virus-induced cytopathic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM50288364(CHEMBL4160695)
Affinity DataEC50:  84nMAssay Description:Inhibition of protease L10F/V32I/M46I/I47V/Q58E/I84V mutant in HIV1 A17 infected in human MT4 cells assessed as reduction in virus-induced cytopathic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM50288360(CHEMBL4163344)
Affinity DataEC50:  95nMAssay Description:Inhibition of protease L10F/V32I/M46I/I47V/Q58E/I84V mutant in HIV1 A17 infected in human MT4 cells assessed as reduction in virus-induced cytopathic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM8125((3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-[(2S...)
Affinity DataEC50:  112nMAssay Description:Inhibition of DRV-resistant protease V32I/L33F/I54M/I84V mutant in HIV1 transfected in 293T cells after 48 hrs by lentiviral vector-based luciferase ...More data for this Ligand-Target Pair
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM50088504(A-84538 | ABBOTT-84538 | CHEBI:45409 | Norvir | Ri...)
Affinity DataEC50:  150nMAssay Description:Inhibition of HIV1 3B protease infected in human MT4 cells assessed as protection from virus induced cytopathogenicity measured after 5 days post inf...More data for this Ligand-Target Pair
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM50288356(CHEMBL4168317)
Affinity DataEC50:  165nMAssay Description:Inhibition of protease L10F/V32I/M46I/I47V/Q58E/I84V mutant in HIV1 A17 infected in human MT4 cells assessed as reduction in virus-induced cytopathic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM50276247(CHEMBL4126567)
Affinity DataEC50:  170nMAssay Description:Inhibition of HIV1 3B protease infected in human MT4 cells assessed as protection from virus induced cytopathogenicity measured after 5 days post inf...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM50288362(CHEMBL4160405)
Affinity DataEC50:  226nMAssay Description:Inhibition of protease L10F/V32I/M46I/I47V/Q58E/I84V mutant in HIV1 A17 infected in human MT4 cells assessed as reduction in virus-induced cytopathic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM50288365(CHEMBL4165197)
Affinity DataEC50:  309nMAssay Description:Inhibition of protease L10F/V32I/M46I/I47V/Q58E/I84V mutant in HIV1 A17 infected in human MT4 cells assessed as reduction in virus-induced cytopathic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM50276248(CHEMBL4127959)
Affinity DataEC50:  550nMAssay Description:Inhibition of HIV1 3B protease infected in human MT4 cells assessed as protection from virus induced cytopathogenicity measured after 5 days post inf...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM50288345(CHEMBL4159139)
Affinity DataEC50:  678nMAssay Description:Inhibition of protease L10F/V32I/M46I/I47V/Q58E/I84V mutant in HIV1 A17 infected in human MT4 cells assessed as reduction in virus-induced cytopathic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM50288347(CHEMBL4160986)
Affinity DataEC50:  1.10E+3nMAssay Description:Inhibition of protease L10F/V32I/M46I/I47V/Q58E/I84V mutant in HIV1 A17 infected in human MT4 cells assessed as reduction in virus-induced cytopathic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM50180655(A-157378-0 | A-157378.0 | ABT-378 | CHEBI:31781 | ...)
Affinity DataEC50:  1.16E+3nMAssay Description:Inhibition of protease L10F/V32I/M46I/I47V/Q58E/I84V mutant in HIV1 A17 infected in human MT4 cells assessed as reduction in virus-induced cytopathic...More data for this Ligand-Target Pair
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM580((4R)-3-[(2S,3S)-2-hydroxy-3-[(3-hydroxy-2-methylph...)
Affinity DataEC50:  2.73E+3nMAssay Description:Inhibition of protease L10F/V32I/M46I/I47V/Q58E/I84V mutant in HIV1 A17 infected in human MT4 cells assessed as reduction in virus-induced cytopathic...More data for this Ligand-Target Pair