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Found 24 of ic50 for UniProtKB: P0C6X4
TargetReplicase polyprotein 1ab(HCoV-HKU1)
The University of Arizona

LigandPNGBDBM448319(GC-376 | GC376)
Affinity DataIC50:  12nMAssay Description:Enzymatic inhibition of GC-376, UAWJ9-36-1, and UAWJ9-36-3 against Mpro's from all seven human coronaviruses. Data fittings of the proteolytic progre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(HCoV-HKU1)
The University of Arizona

LigandPNGBDBM484195(UAWJ9-36-3)
Affinity DataIC50:  100nMAssay Description:Enzymatic inhibition of GC-376, UAWJ9-36-1, and UAWJ9-36-3 against Mpro's from all seven human coronaviruses. Data fittings of the proteolytic progre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(HCoV-HKU1)
The University of Arizona

LigandPNGBDBM484194(UAWJ9-36-1)
Affinity DataIC50:  120nMAssay Description:Enzymatic inhibition of GC-376, UAWJ9-36-1, and UAWJ9-36-3 against Mpro's from all seven human coronaviruses. Data fittings of the proteolytic progre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(HCoV-HKU1)
The University of Arizona

LigandPNGBDBM420363(US9975885, Compound 14)
Affinity DataIC50:  1.80E+3nMAssay Description:The inhibitor library was first screened for inhibition of each 3CLpro at a concentration of 100 μM in duplicate assays containing the following...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetReplicase polyprotein 1ab(HCoV-HKU1)
The University of Arizona

LigandPNGBDBM420986(US9975885, Compound 39)
Affinity DataIC50:  2.00E+3nMAssay Description:The inhibitor library was first screened for inhibition of each 3CLpro at a concentration of 100 μM in duplicate assays containing the following...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetReplicase polyprotein 1ab(HCoV-HKU1)
The University of Arizona

LigandPNGBDBM420352(US9975885, Compound 13)
Affinity DataIC50:  2.50E+3nMAssay Description:The inhibitor library was first screened for inhibition of each 3CLpro at a concentration of 100 μM in duplicate assays containing the following...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetReplicase polyprotein 1ab(HCoV-HKU1)
The University of Arizona

LigandPNGBDBM420993(US9975885, Compound 47)
Affinity DataIC50:  3.40E+3nMAssay Description:The inhibitor library was first screened for inhibition of each 3CLpro at a concentration of 100 μM in duplicate assays containing the following...More data for this Ligand-Target Pair
Ligand InfoPDB
In DepthDetails US Patent
TargetReplicase polyprotein 1ab(HCoV-HKU1)
The University of Arizona

LigandPNGBDBM420960(US9975885, Compound 19)
Affinity DataIC50:  3.70E+3nMAssay Description:The inhibitor library was first screened for inhibition of each 3CLpro at a concentration of 100 μM in duplicate assays containing the following...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetReplicase polyprotein 1ab(HCoV-HKU1)
The University of Arizona

LigandPNGBDBM420996(US9975885, Compound 77)
Affinity DataIC50:  5.00E+3nMAssay Description:The inhibitor library was first screened for inhibition of each 3CLpro at a concentration of 100 μM in duplicate assays containing the following...More data for this Ligand-Target Pair
Ligand InfoPurchasePDB
In DepthDetails US Patent
TargetReplicase polyprotein 1ab(HCoV-HKU1)
The University of Arizona

LigandPNGBDBM420988(US9975885, Compound 41)
Affinity DataIC50:  5.00E+3nMAssay Description:The inhibitor library was first screened for inhibition of each 3CLpro at a concentration of 100 μM in duplicate assays containing the following...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetReplicase polyprotein 1ab(HCoV-HKU1)
The University of Arizona

LigandPNGBDBM420990(US9975885, Compound 43)
Affinity DataIC50:  5.80E+3nMAssay Description:The inhibitor library was first screened for inhibition of each 3CLpro at a concentration of 100 μM in duplicate assays containing the following...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetReplicase polyprotein 1ab(HCoV-HKU1)
The University of Arizona

LigandPNGBDBM420981(US9975885, Compound 64)
Affinity DataIC50:  6.50E+3nMAssay Description:The inhibitor library was first screened for inhibition of each 3CLpro at a concentration of 100 μM in duplicate assays containing the following...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetReplicase polyprotein 1ab(HCoV-HKU1)
The University of Arizona

LigandPNGBDBM420987(US9975885, Compound 40)
Affinity DataIC50:  6.60E+3nMAssay Description:The inhibitor library was first screened for inhibition of each 3CLpro at a concentration of 100 μM in duplicate assays containing the following...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetReplicase polyprotein 1ab(HCoV-HKU1)
The University of Arizona

LigandPNGBDBM420349(US9975885, Compound 6)
Affinity DataIC50:  6.80E+3nMAssay Description:The inhibitor library was first screened for inhibition of each 3CLpro at a concentration of 100 μM in duplicate assays containing the following...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetReplicase polyprotein 1ab(HCoV-HKU1)
The University of Arizona

LigandPNGBDBM420979(US9975885, Compound 34)
Affinity DataIC50:  7.40E+3nMAssay Description:The inhibitor library was first screened for inhibition of each 3CLpro at a concentration of 100 μM in duplicate assays containing the following...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetReplicase polyprotein 1ab(HCoV-HKU1)
The University of Arizona

LigandPNGBDBM420992(US9975885, Compound 46)
Affinity DataIC50:  7.80E+3nMAssay Description:The inhibitor library was first screened for inhibition of each 3CLpro at a concentration of 100 μM in duplicate assays containing the following...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetReplicase polyprotein 1ab(HCoV-HKU1)
The University of Arizona

LigandPNGBDBM420994(US9975885, Compound 48)
Affinity DataIC50:  8.00E+3nMAssay Description:The inhibitor library was first screened for inhibition of each 3CLpro at a concentration of 100 μM in duplicate assays containing the following...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetReplicase polyprotein 1ab(HCoV-HKU1)
The University of Arizona

LigandPNGBDBM420983(US9975885, Compound 3P | med.21724, Compound 125)
Affinity DataIC50:  8.40E+3nMAssay Description:The inhibitor library was first screened for inhibition of each 3CLpro at a concentration of 100 μM in duplicate assays containing the following...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetReplicase polyprotein 1ab(HCoV-HKU1)
The University of Arizona

LigandPNGBDBM420991(US9975885, Compound 44)
Affinity DataIC50:  9.00E+3nMAssay Description:The inhibitor library was first screened for inhibition of each 3CLpro at a concentration of 100 μM in duplicate assays containing the following...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetReplicase polyprotein 1ab(HCoV-HKU1)
The University of Arizona

LigandPNGBDBM420977(US9975885, Compound 32)
Affinity DataIC50:  9.80E+3nMAssay Description:The inhibitor library was first screened for inhibition of each 3CLpro at a concentration of 100 μM in duplicate assays containing the following...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetReplicase polyprotein 1ab(HCoV-HKU1)
The University of Arizona

LigandPNGBDBM420989(US9975885, Compound 42)
Affinity DataIC50:  1.16E+4nMAssay Description:The inhibitor library was first screened for inhibition of each 3CLpro at a concentration of 100 μM in duplicate assays containing the following...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetReplicase polyprotein 1ab(HCoV-HKU1)
The University of Arizona

LigandPNGBDBM420974(US9975885, Compound 30)
Affinity DataIC50:  1.35E+4nMAssay Description:The inhibitor library was first screened for inhibition of each 3CLpro at a concentration of 100 μM in duplicate assays containing the following...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetReplicase polyprotein 1ab(HCoV-HKU1)
The University of Arizona

LigandPNGBDBM420985(US9975885, Compound 38)
Affinity DataIC50:  1.54E+4nMAssay Description:The inhibitor library was first screened for inhibition of each 3CLpro at a concentration of 100 μM in duplicate assays containing the following...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetReplicase polyprotein 1ab(HCoV-HKU1)
The University of Arizona

LigandPNGBDBM420955(US9975885, Compound 54)
Affinity DataIC50:  2.00E+4nMAssay Description:The inhibitor library was first screened for inhibition of each 3CLpro at a concentration of 100 μM in duplicate assays containing the following...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent