Affinity DataKd: 0.530nMAssay Description:Binding constant for CDK2 kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 1.30nMAssay Description:Binding affinity to recombinant CDK2 (unknown origin) assessed as dissociation constant by DSF assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.40nMAssay Description:Compounds in DMSO (1% final) were added to 384-well black clear bottom plates (Greiner 781091) in 8-point dose response in duplicate using the Echo 5...More data for this Ligand-Target Pair
Affinity DataKd: 5nMAssay Description:Binding affinity to CDK2 (unknown origin) at 20 to 80 degC by circular dichroism analysisMore data for this Ligand-Target Pair
Affinity DataKd: 7nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 7nMAssay Description:Binding constant for CDK2 kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 7nMAssay Description:Binding constant for full-length CDK2More data for this Ligand-Target Pair
Affinity DataKd: 7.30nMAssay Description:Compounds in DMSO (1% final) were added to 384-well black clear bottom plates (Greiner 781091) in 8-point dose response in duplicate using the Echo 5...More data for this Ligand-Target Pair
Affinity DataKd: 7.40nMAssay Description:Briefly, a Biacore S200 (Cytiva) at 20° C. and CM5 chips were used for binding analysis. Multi-cycle runs were used for small molecule binding analys...More data for this Ligand-Target Pair
Affinity DataKd: 8.10nMAssay Description:Average Binding Constant for CDK2; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
Affinity DataKd: 10nMAssay Description:Compounds in DMSO (1% final) were added to 384-well black clear bottom plates (Greiner 781091) in 8-point dose response in duplicate using the Echo 5...More data for this Ligand-Target Pair
Affinity DataKd: 18nMAssay Description:Briefly, a Biacore S200 (Cytiva) at 20° C. and CM5 chips were used for binding analysis. Multi-cycle runs were used for small molecule binding analys...More data for this Ligand-Target Pair
Affinity DataKd: 18nMAssay Description:Binding affinity to CDK2 (unknown origin) by isothermal titration calorimetryMore data for this Ligand-Target Pair
Affinity DataKd: 20nMAssay Description:Binding constant for CDK2 kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 20nMAssay Description:Binding affinity to CDK2More data for this Ligand-Target Pair
Affinity DataKd: 20nMAssay Description:Compounds in DMSO (1% final) were added to 384-well black clear bottom plates (Greiner 781091) in 8-point dose response in duplicate using the Echo 5...More data for this Ligand-Target Pair
Affinity DataKd: 23nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 23nMAssay Description:Briefly, a Biacore S200 (Cytiva) at 20° C. and CM5 chips were used for binding analysis. Multi-cycle runs were used for small molecule binding analys...More data for this Ligand-Target Pair
Affinity DataKd: 23nMAssay Description:Binding constant for full-length CDK2More data for this Ligand-Target Pair
Affinity DataKd: 24nMAssay Description:Compounds in DMSO (1% final) were added to 384-well black clear bottom plates (Greiner 781091) in 8-point dose response in duplicate using the Echo 5...More data for this Ligand-Target Pair
Affinity DataKd: 25nMAssay Description:Binding affinity to CDK2 (unknown origin) at 20 to 80 degC by circular dichroism analysisMore data for this Ligand-Target Pair
Affinity DataKd: 30nMAssay Description:Binding constant for CDK2 kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 31nMAssay Description:Briefly, a Biacore S200 (Cytiva) at 20° C. and CM5 chips were used for binding analysis. Multi-cycle runs were used for small molecule binding analys...More data for this Ligand-Target Pair
Affinity DataKd: 40nMAssay Description:Binding affinity to CDK2 (unknown origin) at 20 to 80 degC by circular dichroism analysisMore data for this Ligand-Target Pair
Affinity DataKd: 48nMAssay Description:Binding affinity to CDK2 (unknown origin) at 20 to 80 degC by circular dichroism analysisMore data for this Ligand-Target Pair
Affinity DataKd: 50nMAssay Description:Binding affinity to human CDK2 by isothermal titration calorimetric analysisMore data for this Ligand-Target Pair
Affinity DataKd: 50nMpH: 7.5 T: 2°CAssay Description:All ITC experiments were performed using a VP-ITC (Microcal, Northampton, MA) instrument at 10 or 15 °C in 50 mM HEPES, pH 7.5, 300 mM NaCl, and 1 mM...More data for this Ligand-Target Pair
Affinity DataKd: 53nMAssay Description:Binding affinity to wild-type CDK2 (unknown origin) expressed in baculovirus infected Sf9 insect cells by isothermal titration calorimetric methodMore data for this Ligand-Target Pair
Affinity DataKd: 55nMAssay Description:Binding affinity to human CDK2 by isothermal titration calorimetric analysisMore data for this Ligand-Target Pair
Affinity DataKd: 69nMAssay Description:Binding constant for full-length CDK2More data for this Ligand-Target Pair
Affinity DataKd: 69nMAssay Description:Binding constant for CDK2 kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 69nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 76nMAssay Description:Binding affinity to CDK2 (unknown origin) at 20 to 80 degC by circular dichroism analysisMore data for this Ligand-Target Pair
Affinity DataKd: 88nMpH: 7.5 T: 2°CAssay Description:ThermofluorMore data for this Ligand-Target Pair