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TargetTyrosine-protein kinase Fer(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 0.203nMAssay Description:Inhibition of human FER using poly[Glu:Tyr] (4:1) as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase Fer(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50647628(CHEMBL5597957)
Affinity DataIC50: 0.320nMAssay Description:Inhibition of N-terminal His-tagged recombinant human FER using FL-Peptide22 as substrate incubated for 90 mins in presence of ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
TargetTyrosine-protein kinase Fer(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50647626(CHEMBL5598347)
Affinity DataIC50: 0.350nMAssay Description:Inhibition of N-terminal His-tagged recombinant human FER using FL-Peptide22 as substrate incubated for 90 mins in presence of ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
TargetTyrosine-protein kinase Fer(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 0.365nMAssay Description:Inhibition of human FER using poly[Glu:Tyr] (4:1) as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase Fer(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50647627(CHEMBL5598005)
Affinity DataIC50: 0.420nMAssay Description:Inhibition of N-terminal His-tagged recombinant human FER using FL-Peptide22 as substrate incubated for 90 mins in presence of ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
TargetTyrosine-protein kinase Fer(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50501949(CHEMBL4461851)
Affinity DataIC50: 0.490nMAssay Description:Inhibition of recombinant N-terminal His-tagged human FER (SH2 domain to C-terminal) expressed in Escherichia coli assessed as decrease in FL-Peptide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase Fer(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50647620(CHEMBL5596211)
Affinity DataIC50: 0.490nMAssay Description:Inhibition of N-terminal His-tagged recombinant human FER using FL-Peptide22 as substrate incubated for 90 mins in presence of ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
TargetTyrosine-protein kinase Fer(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50592745(CHEMBL5188373)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of FER (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetTyrosine-protein kinase Fer(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50185140(AP-26113 | Brigatinib | US11248003, Example Brigat...)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human FER using poly (Glu, Tyr)4:1 as substrate in presence of [gamma33P]-ATP by HotSpot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
TargetTyrosine-protein kinase Fer(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of FER (unknown origin) incubated for 1 hr by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2017
Entry Details Article
PubMed
TargetTyrosine-protein kinase Fer(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50520589(CHEMBL4473365)
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant GST/His-tagged human FER catalytic domain expressed in baculovirus expression system by Z-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase Fer(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50448785(CHEMBL3128069)
Affinity DataIC50: 2nMAssay Description:Inhibition of FER (unknown origin) using Km levels of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase Fer(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50501965(CHEMBL4457164)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of recombinant N-terminal His-tagged human FER (SH2 domain to C-terminal) expressed in Escherichia coli assessed as decrease in FL-Peptide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase Fer(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50501961(CHEMBL4456804)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of recombinant N-terminal His-tagged human FER (SH2 domain to C-terminal) expressed in Escherichia coli assessed as decrease in FL-Peptide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase Fer(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50647625(CHEMBL5596100)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of N-terminal His-tagged recombinant human FER using FL-Peptide22 as substrate incubated for 90 mins in presence of ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
TargetTyrosine-protein kinase Fer(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50653010(CHEMBL5712062)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of His-tagged recombinant FER (541 to 822 residues) (unknown origin) expressed in baculovirus expression systemMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
TargetTyrosine-protein kinase Fer(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50018830(CHEMBL3286830 | US10543199, Compound PF-06463922 |...)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of FER (unknown origin) by TR-FRET-based Z'-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetTyrosine-protein kinase Fer(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM130909(US8822500, Stauro- sporine | US9920060, Staurospor...)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of human FER using poly[Glu:Tyr] (4:1) as substrate preincubated for 20 mins followed by [gamma-33P]-ATP addition and measured after 120 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
TargetTyrosine-protein kinase Fer(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50647621(CHEMBL5598480)
Affinity DataIC50: 4nMAssay Description:Inhibition of N-terminal His-tagged recombinant human FER using FL-Peptide22 as substrate incubated for 90 mins in presence of ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
TargetTyrosine-protein kinase Fer(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50501963(CHEMBL4524587)
Affinity DataIC50: 4.70nMAssay Description:Inhibition of recombinant N-terminal His-tagged human FER (SH2 domain to C-terminal) expressed in Escherichia coli assessed as decrease in FL-Peptide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase Fer(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50647623(CHEMBL5589677)
Affinity DataIC50: 4.70nMAssay Description:Inhibition of N-terminal His-tagged recombinant human FER using FL-Peptide22 as substrate incubated for 90 mins in presence of ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
TargetTyrosine-protein kinase Fer(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50647624(CHEMBL5596289)
Affinity DataIC50: 9.10nMAssay Description:Inhibition of N-terminal His-tagged recombinant human FER using FL-Peptide22 as substrate incubated for 90 mins in presence of ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
TargetTyrosine-protein kinase Fer(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50501959(CHEMBL4557212)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant N-terminal His-tagged human FER (SH2 domain to C-terminal) expressed in Escherichia coli assessed as decrease in FL-Peptide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase Fer(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50256480(N-(2,6-difluorophenyl)-5-(3-(2-(5-ethyl-2-methoxy-...)
Affinity DataIC50: 13nMAssay Description:Inhibition of N-terminal His6 tagged recombinant human Fer (541 to end residues) expressed in baculovirus infected Sf21 cells by filter binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
TargetTyrosine-protein kinase Fer(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50501957(CHEMBL4455220)
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant N-terminal His-tagged human FER (SH2 domain to C-terminal) expressed in Escherichia coli assessed as decrease in FL-Peptide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase Fer(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50501950(CHEMBL4548027)
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant N-terminal His-tagged human FER (SH2 domain to C-terminal) expressed in Escherichia coli assessed as decrease in FL-Peptide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase Fer(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50501960(CHEMBL4564799)
Affinity DataIC50: 31nMAssay Description:Inhibition of recombinant N-terminal His-tagged human FER (SH2 domain to C-terminal) expressed in Escherichia coli assessed as decrease in FL-Peptide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase Fer(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50652978(CHEMBL5705846)
Affinity DataIC50: 36nMAssay Description:Inhibition of FER (unknown origin) ACT labeling site by KiNativ Profiling analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
TBA
Entry Details
TargetTyrosine-protein kinase Fer(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50647622(CHEMBL5596072)
Affinity DataIC50: 40nMAssay Description:Inhibition of N-terminal His-tagged recombinant human FER using FL-Peptide22 as substrate incubated for 90 mins in presence of ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
TargetTyrosine-protein kinase Fer(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50204290(CHEMBL3979920 | US11077111, Compound IIIa | US2023...)
Affinity DataIC50: 51nMAssay Description:Inhibition of human recombinant FER cytoplasmic domain (541 to 822 residues) expressed in baculovirus expression system by Z'-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2018
Entry Details Article
PubMed
TargetTyrosine-protein kinase Fer(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50501948(CHEMBL4470327)
Affinity DataIC50: 57nMAssay Description:Inhibition of recombinant N-terminal His-tagged human FER (SH2 domain to C-terminal) expressed in Escherichia coli assessed as decrease in FL-Peptide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase Fer(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50652976(CHEMBL5705830)
Affinity DataIC50: 75nMAssay Description:Inhibition of FER (unknown origin) ACT labeling site by KiNativ Profiling analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
TargetTyrosine-protein kinase Fer(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50515041(CHEMBL4125960)
Affinity DataIC50: 82nMAssay Description:Inhibition of FER (unknown origin) ACT labeling site by KiNativ Profiling analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
TargetTyrosine-protein kinase Fer(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50389154(CHEMBL2064666)
Affinity DataIC50: 85nMAssay Description:Inhibition of human FerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase Fer(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50501956(CHEMBL4475591)
Affinity DataIC50: 210nMAssay Description:Inhibition of recombinant N-terminal His-tagged human FER (SH2 domain to C-terminal) expressed in Escherichia coli assessed as decrease in FL-Peptide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase Fer(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM185674(Rebastinib | 4-[4-[(5-tert-butyl-2-quinolin-6-ylpy...)
Affinity DataIC50: 270nMAssay Description:Inhibition of human wild type FER using PolyEY as substrate preincubated for 2 hrs followed by ATP addition and measured every 2 mins for 2.5 hrs by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
TargetTyrosine-protein kinase Fer(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50501954(CHEMBL4456510)
Affinity DataIC50: 410nMAssay Description:Inhibition of recombinant N-terminal His-tagged human FER (SH2 domain to C-terminal) expressed in Escherichia coli assessed as decrease in FL-Peptide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase Fer(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50501955(CHEMBL4552333)
Affinity DataIC50: 440nMAssay Description:Inhibition of recombinant N-terminal His-tagged human FER (SH2 domain to C-terminal) expressed in Escherichia coli assessed as decrease in FL-Peptide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase Fer(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50501966(CHEMBL4531557)
Affinity DataIC50: 440nMAssay Description:Inhibition of recombinant N-terminal His-tagged human FER (SH2 domain to C-terminal) expressed in Escherichia coli assessed as decrease in FL-Peptide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase Fer(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50501953(CHEMBL4548125)
Affinity DataIC50: 460nMAssay Description:Inhibition of recombinant N-terminal His-tagged human FER (SH2 domain to C-terminal) expressed in Escherichia coli assessed as decrease in FL-Peptide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase Fer(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50501964(CHEMBL4553573)
Affinity DataIC50: 480nMAssay Description:Inhibition of recombinant N-terminal His-tagged human FER (SH2 domain to C-terminal) expressed in Escherichia coli assessed as decrease in FL-Peptide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase Fer(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM4552(CHEMBL288441 | SKI-606 | 4-[(2,4-Dichloro-5-methox...)
Affinity DataIC50: 490nMAssay Description:Inhibition of FERMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase Fer(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50501951(CHEMBL4517783)
Affinity DataIC50: 510nMAssay Description:Inhibition of recombinant N-terminal His-tagged human FER (SH2 domain to C-terminal) expressed in Escherichia coli assessed as decrease in FL-Peptide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase Fer(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM439310(US10633348, Compound (A-8))
Affinity DataIC50: 577nMAssay Description:Inhibition of FER (unknown origin) ACT labeling site by KiNativ Profiling analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
TBA
Entry Details
TargetTyrosine-protein kinase Fer(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50637925(CHEMBL5559304)
Affinity DataIC50: 802nMAssay Description:Inhibition of FER (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
TargetTyrosine-protein kinase Fer(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM174948(US9096593, P-2049)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of FER (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
TargetTyrosine-protein kinase Fer(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50462709(CHEMBL4245507)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of FER (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase Fer(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50311017(N-(cyanomethyl)-4-(2-(4-morpholinophenylamino)pyri...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of FER (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
TargetTyrosine-protein kinase Fer(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50501967(CHEMBL4474508)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of recombinant N-terminal His-tagged human FER (SH2 domain to C-terminal) expressed in Escherichia coli assessed as decrease in FL-Peptide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase Fer(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM97672(US8476284, 40 | US9133201, 10 | US9181263, 9 | US9...)
Affinity DataIC50: 3.35E+3nMAssay Description:IC50s were determined using the in vitro HotSpot kinase assay (purified enzymes, 33P-ATP, an appropriate substrate and 1 μM ATP.). For enzyme in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
US Patent

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