Affinity DataEC50: 0.600nMAssay Description:Agonist activity at LXR-beta in human HeLa cells assessed as induction of ABCA1 by beta-galactosidase/luciferase reporter gene assayMore data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataEC50: 1nMAssay Description:Effective concentration against liver X receptor-beta in HEK293 cell transactivation assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1nMAssay Description:Effective concentration for cofactor association with recombinant liver X receptor-betaMore data for this Ligand-Target Pair
Affinity DataEC50: 1nMAssay Description:Effective concentration in recombinant human LXRbeta ligand binding domain in homogeneous time-resolved fluorescence assay More data for this Ligand-Target Pair
Affinity DataEC50: 1nMAssay Description:Binding to human LXRbetaMore data for this Ligand-Target Pair
Affinity DataEC50: 1nMAssay Description:Agonist activity at LXR-beta in human HeLa cells assessed as induction of ABCA1 by beta-galactosidase/luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1nMAssay Description:Agonist activity at LXRbeta ligand binding domain-mediated transcriptional activity in african green monkey CV1 cells co-transfected with Gal4-SRC1 b...More data for this Ligand-Target Pair
Affinity DataEC50: 2nMAssay Description:Agonist activity at LXR-beta in human HeLa cells assessed as induction of ABCA1 by beta-galactosidase/luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2nMAssay Description:Effective concentration for cofactor association with recombinant liver X receptor-betaMore data for this Ligand-Target Pair
Affinity DataEC50: 2nMAssay Description:Effective concentration in recombinant human LXRbeta ligand binding domain in homogeneous time-resolved fluorescence assay More data for this Ligand-Target Pair
Affinity DataEC50: 2nMAssay Description:Agonist activity at LXR-beta in human HeLa cells assessed as induction of ABCA1 by beta-galactosidase/luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2nMAssay Description:Agonist activity at LXR-beta in human HeLa cells assessed as induction of ABCA1 by beta-galactosidase/luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2nMAssay Description:Transactivation of LXRbeta (unknown origin) expressed in CV1 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: <3nMAssay Description:Effective concentration in transactivation assay using a chimeric LXR construct in HEK-293 cells for LXRbeta receptorMore data for this Ligand-Target Pair
Affinity DataEC50: <3nMAssay Description:Effective concentration for cofactor association with recombinant liver X receptor-betaMore data for this Ligand-Target Pair
Affinity DataEC50: <3nMAssay Description:Effective concentration against liver X receptor-beta in HEK293 cell transactivation assayMore data for this Ligand-Target Pair
Affinity DataEC50: <3nMAssay Description:Agonist activity at human recombinant LXRbeta expressed in Escherichia coli BL21 cells assessed as association of recombinant SRC1 to LXRbeta ligand ...More data for this Ligand-Target Pair
Affinity DataEC50: 3nMAssay Description:Agonist activity at LXR-beta in human HeLa cells assessed as induction of ABCA1 by beta-galactosidase/luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 3.20nMAssay Description:Agonist activity at LXRbeta ligand binding domain-mediated transcriptional activity in african green monkey CV1 cells co-transfected with Gal4-SRC1 b...More data for this Ligand-Target Pair
Affinity DataEC50: 3.20nMAssay Description:Agonist activity at LXRbeta ligand binding domain-mediated transcriptional activity in african green monkey CV1 cells co-transfected with Gal4-SRC1 b...More data for this Ligand-Target Pair
Affinity DataEC50: 4nMAssay Description:This assay is based on the ability of the LXR-LBDs (LXRα and LXRβ) to recruit and interact with a co-activator peptide. This assay was run ...More data for this Ligand-Target Pair
Affinity DataEC50: 4nMpH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
Affinity DataEC50: 4nMAssay Description:This assay is based on the ability of the LXR-LBDs (LXRα and LXRβ) to recruit and interact with a co-activator peptide. This assay was run ...More data for this Ligand-Target Pair
Affinity DataEC50: 4.70nMAssay Description:Agonist activity at LXRbeta by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataEC50: 5nMAssay Description:Agonist activity at LXR-beta in human whole blood assessed as ABCA1 gene induction by measuring ABCA1 mRNA level after 4 hrs by SYBR-Green dye-based ...More data for this Ligand-Target Pair
Affinity DataEC50: 5nMAssay Description:Agonist activity at LXR-beta in human HeLa cells assessed as induction of ABCA1 by beta-galactosidase/luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 5nMAssay Description:Binding to human LXRbetaMore data for this Ligand-Target Pair
Affinity DataEC50: 6nMpH: 7.2 T: 2°CAssay Description:FRET-based co-activator recruitment assay measures agonist activities in a 384-well plate format. Reaction mixture containing His-tagged hLXR, biotin...More data for this Ligand-Target Pair
Affinity DataEC50: 6nMAssay Description:This assay is based on the ability of the LXR-LBDs (LXRα and LXRβ) to recruit and interact with a co-activator peptide. This assay was run ...More data for this Ligand-Target Pair
Affinity DataEC50: 7nMAssay Description:Agonist activity at LXRbeta (unknown origin) expressed in human H4 cells co-expressing ABCA1 promoter measured after 48 hrs by cell-based transactiva...More data for this Ligand-Target Pair
Affinity DataEC50: 7nMpH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
Affinity DataEC50: 7nMAssay Description:Agonist activity at GAL4 fused LXRbeta-LBD (unknown origin) transfected in CHOK1 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 8nMAssay Description:Agonist activity at LXR-beta in human HeLa cells assessed as induction of ABCA1 by beta-galactosidase/luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 8nMAssay Description:Agonist activity at LXRbeta ligand binding domain (unknown origin) by FRET based SRC1 recruitment assayMore data for this Ligand-Target Pair
Affinity DataEC50: 8nMAssay Description:Agonist activity at LXR-beta in human HeLa cells assessed as induction of ABCA1 by beta-galactosidase/luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 8nMAssay Description:Agonist activity at GST-tagged LXRbeta-LBD (unknown origin) by LanthaScreen TR-FRET liver X receptor coactivator assayMore data for this Ligand-Target Pair
Affinity DataEC50: 9nMAssay Description:Agonist activity at LXR-beta in human whole blood assessed as ABCA1 gene induction by measuring ABCA1 mRNA level after 4 hrs by SYBR-Green dye-based ...More data for this Ligand-Target Pair
Affinity DataEC50: 9nMAssay Description:This assay is based on the ability of the LXR-LBDs (LXRα and LXRβ) to recruit and interact with a co-activator peptide. This assay was run ...More data for this Ligand-Target Pair
Affinity DataEC50: 9nMAssay Description:Agonist activity at LXR-beta in human HeLa cells assessed as induction of ABCA1 by beta-galactosidase/luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 10nMAssay Description:Agonist activity at human LXR-betaMore data for this Ligand-Target Pair
Affinity DataEC50: 10nMAssay Description:Agonist activity at LXR-beta in human whole blood assessed as ABCG1 gene induction by measuring ABCA1 mRNA level after 4 hrs by SYBR-Green dye-based ...More data for this Ligand-Target Pair
Affinity DataEC50: 10nMAssay Description:Effective concentration in transactivation assay using a chimeric LXR construct in HEK-293 cells for LXRbeta receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 10nMAssay Description:Binding affinity to LXRbeta (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 10nMAssay Description:Effective concentration against liver X receptor-beta in HEK293 cell transactivation assayMore data for this Ligand-Target Pair
Affinity DataEC50: 11nMAssay Description:As used herein, reference to the activity of an LXR agonist at LXRα and LXRβ refer to the activity as measured using the ligand sensing ass...More data for this Ligand-Target Pair
Affinity DataEC50: 11nMAssay Description:Agonist activity at human LXRbeta assessed as association of SRC1 to LXRbeta ligand binding domain by FRET based cell-free ligand sensing assayMore data for this Ligand-Target Pair
Affinity DataEC50: 11nMAssay Description:As used herein, reference to the activity of an LXR agonist at LXRα and LXRβ refer to the activity as measured using the ligand sensing ass...More data for this Ligand-Target Pair
Affinity DataEC50: 12nMAssay Description:Agonist activity at LXR-beta in human HeLa cells assessed as induction of ABCA1 by beta-galactosidase/luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 12nMpH: 7.5 T: 2°CAssay Description:Polyhistidine-tagged human LXR ligand-binding domain was mixed with the test compound, biotin-SRC1 peptide, streptavidin-allophycocyanin, and europiu...More data for this Ligand-Target Pair
Affinity DataEC50: 12nMpH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
