TargetTyrosine-protein kinase ABL2(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 0.780nMAssay Description:Inhibition of Abl kinaseMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL2(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of Abl2 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibition of Abl kinaseMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL2(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of Abl2 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.90nMAssay Description:Inhibition of Abl kinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 2.90nMAssay Description:Inhibition of Abl kinaseMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL2(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of Abl2 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.5nMAssay Description:Inhibition of Abl kinaseMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL2(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant ARG (38 to end residues) using EAIYAAPFAKKK as substrate incubated for 40 mins in presence of [gamma33P-ATP] by radio...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL2(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:The aim of this experiment is to detect the inhibitory activity of the compounds of the present invention against in vitro protein kinases using isot...More data for this Ligand-Target Pair
Affinity DataIC50: 4.60nMAssay Description:Inhibition of Abl kinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of v-Abl tyrosine kinase activityMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL2(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of Abl2 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL2(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of Abl2 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 ...More data for this Ligand-Target Pair
Affinity DataIC50: 8.30nMAssay Description:Inhibition of Abl kinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 8.30nMAssay Description:Inhibition of Abl kinaseMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL2(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of Abl2 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 ...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of v-Abl tyrosine kinase activityMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL2(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 10.1nMAssay Description:Inhibition of human ABL2 using EAIYAAPFAKKK as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL2(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of Abl2 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL2(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of Abl2 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 ...More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of Abl kinaseMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL2(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of Abl2 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL2(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of Abl2 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL2(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 15.8nMAssay Description:Inhibition of human ABL2 using EAIYAAPFAKKK as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of Abl kinaseMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL2(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of Abl2 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 ...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of PDGF-receptor kinaseMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL2(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Kinase base buffer (50 mM HEPES, pH 7.5 0.0015% Brij-35; 10 mM MgCl22 mM DTT) and Stop buffer (100 mM HEPES, pH 7.5 0.015% Brij-35; 0.2% Coating Reag...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL2(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Kinase base buffer (50 mM HEPES, pH 7.5 0.0015% Brij-35; 10 mM MgCl2 2 mM DTT) and Stop buffer, (100 mM HEPES, pH 7.5 0.015% Brij-35; 0.2% Coating Re...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL2(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 36nMAssay Description:Inhibition of Abl2 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 ...More data for this Ligand-Target Pair
Affinity DataIC50: 38nMAssay Description:Inhibition of Abl kinaseMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL2(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 39nMAssay Description:Inhibition of Abl2 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL2(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 39nMAssay Description:Kinase base buffer (50 mM HEPES, pH 7.5 0.0015% Brij-35; 10 mM MgCl2 2 mM DTT) and Stop buffer, (100 mM HEPES, pH 7.5 0.015% Brij-35; 0.2% Coating Re...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL2(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 39nMAssay Description:Kinase base buffer (50 mM HEPES, pH 7.5 0.0015% Brij-35; 10 mM MgCl22 mM DTT) and Stop buffer (100 mM HEPES, pH 7.5 0.015% Brij-35; 0.2% Coating Reag...More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of v-Abl tyrosine kinase activityMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL2(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of Abl2 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 ...More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of v-Abl tyrosine kinase activityMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of Abl tyrosine kinaseMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL2(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 41nMAssay Description:Inhibition of Abl2 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL2(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 44.7nMAssay Description:Kinase base buffer (50 mM HEPES, pH 7.5 0.0015% Brij-35; 10 mM MgCl2 2 mM DTT) and Stop buffer, (100 mM HEPES, pH 7.5 0.015% Brij-35; 0.2% Coating Re...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL2(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 44.7nMAssay Description:Kinase base buffer (50 mM HEPES, pH 7.5 0.0015% Brij-35; 10 mM MgCl22 mM DTT) and Stop buffer (100 mM HEPES, pH 7.5 0.015% Brij-35; 0.2% Coating Reag...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL2(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 47nMAssay Description:Inhibition of Abl2 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 ...More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of p60 c-Src tyrosine kinase mediated phosphorylation of Fak in IC8.1 fibroblastsMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Tested in vitro for inhibition of non-receptor tyrosine kinase v-AblMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL2(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 50.1nMAssay Description:Kinase base buffer (50 mM HEPES, pH 7.5 0.0015% Brij-35; 10 mM MgCl22 mM DTT) and Stop buffer (100 mM HEPES, pH 7.5 0.015% Brij-35; 0.2% Coating Reag...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL2(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 50.1nMAssay Description:Kinase base buffer (50 mM HEPES, pH 7.5 0.0015% Brij-35; 10 mM MgCl2 2 mM DTT) and Stop buffer, (100 mM HEPES, pH 7.5 0.015% Brij-35; 0.2% Coating Re...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL2(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 51nMAssay Description:Kinase base buffer (50 mM HEPES, pH 7.5 0.0015% Brij-35; 10 mM MgCl22 mM DTT) and Stop buffer (100 mM HEPES, pH 7.5 0.015% Brij-35; 0.2% Coating Reag...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL2(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 51nMAssay Description:Kinase base buffer (50 mM HEPES, pH 7.5 0.0015% Brij-35; 10 mM MgCl2 2 mM DTT) and Stop buffer, (100 mM HEPES, pH 7.5 0.015% Brij-35; 0.2% Coating Re...More data for this Ligand-Target Pair