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TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50402010(CHEMBL2205419)
Affinity DataKi:  0.163nMAssay Description:Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellum membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50060964((R)-5-(2-((2-(2-ethoxyphenoxy)ethyl)amino)propyl)-...)
Affinity DataKi:  0.180nMAssay Description:Displacement of [125I] HEAT from human alpha1D adrenergic receptor expressed in Chlorocebus aethiops COS1 cell membranes incubated for 60 mins by liq...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50387549(CHEMBL2057693)
Affinity DataKi:  0.180nMAssay Description:Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50402009(CHEMBL2205420)
Affinity DataKi:  0.303nMAssay Description:Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellum membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(MOUSE)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50402010(CHEMBL2205419)
Affinity DataKi:  0.324nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain membranes without cerebellumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50402011(CHEMBL2205418)
Affinity DataKi:  0.340nMAssay Description:Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellum membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50402008(CHEMBL2205421)
Affinity DataKi:  0.340nMAssay Description:Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellum membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50274519((2E)-N-[(5R,6R)-17-(Cyclopropylmethyl)-4,5-epoxy-3...)
Affinity DataKi:  0.350nMAssay Description:Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(MOUSE)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50387549(CHEMBL2057693)
Affinity DataKi:  0.430nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in mouse cerebellumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50402017(CHEMBL2205412)
Affinity DataKi:  0.451nMAssay Description:Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellum membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(MOUSE)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50274519((2E)-N-[(5R,6R)-17-(Cyclopropylmethyl)-4,5-epoxy-3...)
Affinity DataKi:  0.510nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in mouse cerebellumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(MOUSE)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50274401((2E)-N-[(5R,6S)-17-(Cyclopropylmethyl)-4,5-epoxy-3...)
Affinity DataKi:  0.560nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain membranes without cerebellumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50402010(CHEMBL2205419)
Affinity DataKi:  0.623nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain membranes without cerebellumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50164686(CHEMBL3798124)
Affinity DataKi:  0.660nMAssay Description:Displacement of 7-methoxy-[3H]-prazosin from human alpha1D adrenergic receptor expressed in CHO-K1 cell membranes incubated for 60 mins by liquid sci...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50274401((2E)-N-[(5R,6S)-17-(Cyclopropylmethyl)-4,5-epoxy-3...)
Affinity DataKi:  0.710nMAssay Description:Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellum membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50402016(CHEMBL2205413)
Affinity DataKi:  0.711nMAssay Description:Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellum membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50402018(CHEMBL2204731)
Affinity DataKi:  0.733nMAssay Description:Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellum membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50164745(CHEMBL3800606)
Affinity DataKi:  0.860nMAssay Description:Displacement of 7-methoxy-[3H]-prazosin from human alpha1D adrenergic receptor expressed in CHO-K1 cell membranes incubated for 60 mins by liquid sci...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50274401((2E)-N-[(5R,6S)-17-(Cyclopropylmethyl)-4,5-epoxy-3...)
Affinity DataKi:  1.01nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain membranes without cerebellumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50402019(CHEMBL2204730)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellum membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50164769(CHEMBL3799553)
Affinity DataKi:  1.10nMAssay Description:Displacement of 7-methoxy-[3H]-prazosin from human alpha1D adrenergic receptor expressed in CHO-K1 cell membranes incubated for 60 mins by liquid sci...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50320090((2R,2aS,2a1S,5aR)-2-((cyclopropylmethyl)(methyl)am...)
Affinity DataKi:  1.17nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Hartley guinea pig forebrain by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50164687(CHEMBL3799292)
Affinity DataKi:  1.60nMAssay Description:Displacement of 7-methoxy-[3H]-prazosin from human alpha1D adrenergic receptor expressed in CHO-K1 cell membranes incubated for 60 mins by liquid sci...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50402013(CHEMBL2205416)
Affinity DataKi:  2.06nMAssay Description:Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellum membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50387549(CHEMBL2057693)
Affinity DataKi:  2.09nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in mouse cerebellumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50402015(CHEMBL2205414)
Affinity DataKi:  2.23nMAssay Description:Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellum membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50402012(CHEMBL2205417)
Affinity DataKi:  2.28nMAssay Description:Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellum membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50164739(CHEMBL3800305)
Affinity DataKi:  2.60nMAssay Description:Displacement of 7-methoxy-[3H]-prazosin from human alpha1D adrenergic receptor expressed in CHO-K1 cell membranes incubated for 60 mins by liquid sci...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50274482((2E)-N-[(5R,6R)-17-(Cyclopropylmethyl)-4,5-epoxy-1...)
Affinity DataKi:  2.82nMAssay Description:Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50320086((2R,2aR,2a1S,5aR)-2-((cyclopropylmethyl)(methyl)am...)
Affinity DataKi:  3.36nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Hartley guinea pig forebrain by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50164688(CHEMBL3800470)
Affinity DataKi:  3.40nMAssay Description:Displacement of 7-methoxy-[3H]-prazosin from human alpha1D adrenergic receptor expressed in CHO-K1 cell membranes incubated for 60 mins by liquid sci...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50164678(CHEMBL3799912)
Affinity DataKi:  3.70nMAssay Description:Displacement of 7-methoxy-[3H]-prazosin from human alpha1D adrenergic receptor expressed in CHO-K1 cell membranes incubated for 60 mins by liquid sci...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50164765(CHEMBL3800506)
Affinity DataKi:  4.80nMAssay Description:Displacement of 7-methoxy-[3H]-prazosin from human alpha1D adrenergic receptor expressed in CHO-K1 cell membranes incubated for 60 mins by liquid sci...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50320090((2R,2aS,2a1S,5aR)-2-((cyclopropylmethyl)(methyl)am...)
Affinity DataKi:  5.10nMAssay Description:Displacement of [3H]U69493 from kappa opioid receptor in Hartley guinea pig cerebellum by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(MOUSE)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50402019(CHEMBL2204730)
Affinity DataKi:  5.26nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain membranes without cerebellumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(MOUSE)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50402017(CHEMBL2205412)
Affinity DataKi:  5.49nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain membranes without cerebellumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50387553(CHEMBL2057691)
Affinity DataKi:  5.64nMAssay Description:Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50402009(CHEMBL2205420)
Affinity DataKi:  5.65nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain membranes without cerebellumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(MOUSE)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50402009(CHEMBL2205420)
Affinity DataKi:  6.52nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain membranes without cerebellumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50164741(CHEMBL3799420)
Affinity DataKi:  7.5nMAssay Description:Displacement of 7-methoxy-[3H]-prazosin from human alpha1D adrenergic receptor expressed in CHO-K1 cell membranes incubated for 60 mins by liquid sci...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50402019(CHEMBL2204730)
Affinity DataKi:  8.45nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain membranes without cerebellumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50164743(CHEMBL3799166)
Affinity DataKi:  8.5nMAssay Description:Displacement of 7-methoxy-[3H]-prazosin from human alpha1D adrenergic receptor expressed in CHO-K1 cell membranes incubated for 60 mins by liquid sci...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50310297((2R,2aS,2a1S,5aR)-2-(cyclopropylmethylamino)-2a,7-...)
Affinity DataKi:  8.60nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in guinea pig forebrainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(MOUSE)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50402012(CHEMBL2205417)
Affinity DataKi:  8.62nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain membranes without cerebellumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50402017(CHEMBL2205412)
Affinity DataKi:  8.66nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain membranes without cerebellumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50164740(CHEMBL3799089)
Affinity DataKi:  8.70nMAssay Description:Displacement of 7-methoxy-[3H]-prazosin from human alpha1D adrenergic receptor expressed in CHO-K1 cell membranes incubated for 60 mins by liquid sci...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50320086((2R,2aR,2a1S,5aR)-2-((cyclopropylmethyl)(methyl)am...)
Affinity DataKi:  8.81nMAssay Description:Displacement of [3H]U69493 from kappa opioid receptor in Hartley guinea pig cerebellum by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50274519((2E)-N-[(5R,6R)-17-(Cyclopropylmethyl)-4,5-epoxy-3...)
Affinity DataKi:  8.82nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in mouse cerebellumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(MOUSE)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50402011(CHEMBL2205418)
Affinity DataKi:  8.88nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain membranes without cerebellumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50320089((2R,2aS,2a1S,5aR)-2-(dimethylamino)-2a,7-dihydroxy...)
Affinity DataKi:  8.95nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Hartley guinea pig forebrain by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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