Found 10 with your filter TargetSon of sevenless homolog 1(Homo sapiens (Human))
Wuhan University Of Science And Technology
Curated by ChEMBL
Wuhan University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of SOS1 in human DLD-1 cells assessed as reduction in ERK phosphorylation incubated for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
TargetCytochrome P450 2D6(Homo sapiens (Human))
Wuhan University Of Science And Technology
Curated by ChEMBL
Wuhan University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 4.30E+3nMAssay Description:Time-dependent inhibition of CYP2D6 (unknown origin) at 2 ul pre-incubated for 30 mins in presence or absence of NADPH incubated for 10 mins by LC/MS...More data for this Ligand-Target Pair
TargetCytochrome P450 2D6(Homo sapiens (Human))
Wuhan University Of Science And Technology
Curated by ChEMBL
Wuhan University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of CYP2D6 in human liver microsomes at 10 uM using dextromethorphan as substrate preincubated for 10 mins followed by NADPH addition by LC...More data for this Ligand-Target Pair
TargetCytochrome P450 2C9(Homo sapiens (Human))
Wuhan University Of Science And Technology
Curated by ChEMBL
Wuhan University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 1.46E+4nMAssay Description:Time-dependent inhibition of CYP2C9 (unknown origin) at 2 ul pre-incubated for 30 mins in presence or absence of NADPH incubated for 10 mins by LC/MS...More data for this Ligand-Target Pair
TargetCytochrome P450 2C9(Homo sapiens (Human))
Wuhan University Of Science And Technology
Curated by ChEMBL
Wuhan University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 1.54E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomes at 10 uM using diclofenac as substrate preincubated for 10 mins followed by NADPH addition by LC/MS an...More data for this Ligand-Target Pair
TargetCytochrome P450 2C8(Homo sapiens (Human))
Wuhan University Of Science And Technology
Curated by ChEMBL
Wuhan University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 3.91E+4nMAssay Description:Time-dependent inhibition of CYP2C8 (unknown origin) at 2 ul pre-incubated for 30 mins in presence or absence of NADPH incubated for 10 mins by LC/MS...More data for this Ligand-Target Pair
TargetCytochrome P450 2C8(Homo sapiens (Human))
Wuhan University Of Science And Technology
Curated by ChEMBL
Wuhan University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 4.52E+4nMAssay Description:Inhibition of CYP2C8 in human liver microsomes at 10 uM using amodiaquine as substrate preincubated for 10 mins followed by NADPH addition by LC/MS a...More data for this Ligand-Target Pair
TargetCytochrome P450 1A2(Homo sapiens (Human))
Wuhan University Of Science And Technology
Curated by ChEMBL
Wuhan University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CYP1A2 in human liver microsomes at 10 uM using phenacetin as substrate preincubated for 10 mins followed by NADPH addition by LC/MS an...More data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
Wuhan University Of Science And Technology
Curated by ChEMBL
Wuhan University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CYP3A4 in human liver microsomes at 10 uM using midazolam as substrate preincubated for 10 mins followed by NADPH addition by LC/MS ana...More data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
Wuhan University Of Science And Technology
Curated by ChEMBL
Wuhan University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Time-dependent inhibition of CYP3A4 (unknown origin) at 2 ul pre-incubated for 30 mins in presence or absence of NADPH incubated for 10 mins by LC/MS...More data for this Ligand-Target Pair
