Found 4 with your filter TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
University Of Pittsburgh
Curated by ChEMBL
University Of Pittsburgh
Curated by ChEMBL
Affinity DataIC50: 1.20E+4nMAssay Description:Negative allosteric modulator activity at SHP2 (unknown origin)More data for this Ligand-Target Pair
3D Structure (crystal)TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
University Of Pittsburgh
Curated by ChEMBL
University Of Pittsburgh
Curated by ChEMBL
Affinity DataIC50: 1.20E+4nMAssay Description:Allosteric inhibition of 6x-histidine tagged human SHP2 (Met1-L525 residues) expressed in Escherichia coli BL21 Star (DE3) using IRS1_pY1172(dPEG8)pY...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
University Of Pittsburgh
Curated by ChEMBL
University Of Pittsburgh
Curated by ChEMBL
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human 6his-tagged SHP2 (2 to 593 residues) expressed in Escherichia coli BL21 Star (DE3) cells preincubated with IRS1_pY1172(dPEG8)pY12...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
University Of Pittsburgh
Curated by ChEMBL
University Of Pittsburgh
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human SHP2 PTP domain (237 to 529 residues) by fluorescence analysisMore data for this Ligand-Target Pair
