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TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50261301(CHEMBL4072422)
Affinity DataIC50:  32nMAssay Description:Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced calcium mobilization...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50261323(CHEMBL4087545)
Affinity DataIC50:  38nMAssay Description:Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced calcium mobilization...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50261322(CHEMBL4060424)
Affinity DataIC50:  46nMAssay Description:Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced calcium mobilization...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50261327(CHEMBL4083286)
Affinity DataIC50:  50nMAssay Description:Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced calcium mobilization...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50261325(CHEMBL4060556)
Affinity DataIC50:  54nMAssay Description:Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced calcium mobilization...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50261309(CHEMBL4091125)
Affinity DataIC50:  58nMAssay Description:Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced calcium mobilization...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50261310(CHEMBL4102181)
Affinity DataIC50:  63nMAssay Description:Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced calcium mobilization...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50261324(CHEMBL4098822)
Affinity DataIC50:  75nMAssay Description:Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells assessed as L-glutamate-induced intracellular calcium mobilizati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50261324(CHEMBL4098822)
Affinity DataIC50:  75nMAssay Description:Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells assessed as L-glutamate-induced intracellular calcium mobilizati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50261311(CHEMBL4076718)
Affinity DataIC50:  90nMAssay Description:Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced calcium mobilization...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50533084(CHEMBL4447634)
Affinity DataIC50:  127nMAssay Description:Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells assessed as L-glutamate-induced intracellular calcium mobilizati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50533084(CHEMBL4447634)
Affinity DataIC50:  127nMAssay Description:Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells assessed as L-glutamate-induced intracellular calcium mobilizati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50533092(CHEMBL4578292)
Affinity DataIC50:  150nMAssay Description:Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells assessed as L-glutamate-induced intracellular calcium mobilizati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50533092(CHEMBL4578292)
Affinity DataIC50:  150nMAssay Description:Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells assessed as L-glutamate-induced intracellular calcium mobilizati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50533078(CHEMBL4465009)
Affinity DataIC50:  150nMAssay Description:Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells assessed as L-glutamate-induced intracellular calcium mobilizati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50533078(CHEMBL4465009)
Affinity DataIC50:  150nMAssay Description:Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells assessed as L-glutamate-induced intracellular calcium mobilizati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50261321(CHEMBL4061450)
Affinity DataIC50:  157nMAssay Description:Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced calcium mobilization...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50533090(CHEMBL4576019)
Affinity DataIC50:  164nMAssay Description:Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells assessed as L-glutamate-induced intracellular calcium mobilizati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50533090(CHEMBL4576019)
Affinity DataIC50:  164nMAssay Description:Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells assessed as L-glutamate-induced intracellular calcium mobilizati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50261308(CHEMBL4099864)
Affinity DataIC50:  174nMAssay Description:Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced calcium mobilization...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50533088(CHEMBL4459507)
Affinity DataIC50:  176nMAssay Description:Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells assessed as L-glutamate-induced intracellular calcium mobilizati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50533088(CHEMBL4459507)
Affinity DataIC50:  176nMAssay Description:Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells assessed as L-glutamate-induced intracellular calcium mobilizati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50261307(CHEMBL4081862)
Affinity DataIC50:  177nMAssay Description:Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced calcium mobilization...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50533072(CHEMBL4533301)
Affinity DataIC50:  197nMAssay Description:Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells assessed as L-glutamate-induced intracellular calcium mobilizati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50533072(CHEMBL4533301)
Affinity DataIC50:  197nMAssay Description:Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells assessed as L-glutamate-induced intracellular calcium mobilizati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50533087(CHEMBL4539166)
Affinity DataIC50:  201nMAssay Description:Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells assessed as L-glutamate-induced intracellular calcium mobilizati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50533087(CHEMBL4539166)
Affinity DataIC50:  201nMAssay Description:Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells assessed as L-glutamate-induced intracellular calcium mobilizati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50533086(CHEMBL4554361)
Affinity DataIC50:  235nMAssay Description:Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells assessed as L-glutamate-induced intracellular calcium mobilizati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50533086(CHEMBL4554361)
Affinity DataIC50:  235nMAssay Description:Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells assessed as L-glutamate-induced intracellular calcium mobilizati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50261326(CHEMBL4064091)
Affinity DataIC50:  237nMAssay Description:Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced calcium mobilization...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50533073(CHEMBL4447834)
Affinity DataIC50:  244nMAssay Description:Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells assessed as L-glutamate-induced intracellular calcium mobilizati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50533073(CHEMBL4447834)
Affinity DataIC50:  244nMAssay Description:Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells assessed as L-glutamate-induced intracellular calcium mobilizati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50533077(CHEMBL4438775)
Affinity DataIC50:  257nMAssay Description:Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells assessed as L-glutamate-induced intracellular calcium mobilizati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50533077(CHEMBL4438775)
Affinity DataIC50:  257nMAssay Description:Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells assessed as L-glutamate-induced intracellular calcium mobilizati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50533091(CHEMBL4439186)
Affinity DataIC50:  270nMAssay Description:Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells assessed as L-glutamate-induced intracellular calcium mobilizati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50533091(CHEMBL4439186)
Affinity DataIC50:  270nMAssay Description:Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells assessed as L-glutamate-induced intracellular calcium mobilizati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50533075(CHEMBL4466105)
Affinity DataIC50:  383nMAssay Description:Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells assessed as L-glutamate-induced intracellular calcium mobilizati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50533075(CHEMBL4466105)
Affinity DataIC50:  383nMAssay Description:Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells assessed as L-glutamate-induced intracellular calcium mobilizati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50261300(CHEMBL4084362)
Affinity DataIC50:  403nMAssay Description:Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced calcium mobilization...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50533080(CHEMBL4469833)
Affinity DataIC50:  451nMAssay Description:Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells assessed as L-glutamate-induced intracellular calcium mobilizati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50533080(CHEMBL4469833)
Affinity DataIC50:  451nMAssay Description:Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells assessed as L-glutamate-induced intracellular calcium mobilizati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50533085(CHEMBL4591221)
Affinity DataIC50:  477nMAssay Description:Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells assessed as L-glutamate-induced intracellular calcium mobilizati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50533085(CHEMBL4591221)
Affinity DataIC50:  477nMAssay Description:Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells assessed as L-glutamate-induced intracellular calcium mobilizati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50533076(CHEMBL4540164)
Affinity DataIC50:  482nMAssay Description:Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells assessed as L-glutamate-induced intracellular calcium mobilizati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50533076(CHEMBL4540164)
Affinity DataIC50:  482nMAssay Description:Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells assessed as L-glutamate-induced intracellular calcium mobilizati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50533079(CHEMBL4562313)
Affinity DataIC50:  568nMAssay Description:Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells assessed as L-glutamate-induced intracellular calcium mobilizati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50533079(CHEMBL4562313)
Affinity DataIC50:  568nMAssay Description:Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells assessed as L-glutamate-induced intracellular calcium mobilizati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50320089((2R,2aS,2a1S,5aR)-2-(dimethylamino)-2a,7-dihydroxy...)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [3H]U69493 from kappa opioid receptor in Hartley guinea pig cerebellum by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50320091((1R,5S,10R,18S)-9-(cyclopropylmethyl)-15-hydroxy-6...)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [3H]U69493 from kappa opioid receptor in Hartley guinea pig cerebellum by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50320092((1R,5S,10R,18S)-15-hydroxy-9-methyl-6,19-dioxa-9-a...)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [3H]U69493 from kappa opioid receptor in Hartley guinea pig cerebellum by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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