Compile Data Set for Download or QSAR
maximum 50k data
Found 31 Enz. Inhib. hit(s) with all data for entry = 4370
TargetPotassium voltage-gated channel subfamily KQT member 2(Rattus norvegicus)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM65922(1-(2,4-dichlorobenzyl)-3-phenyl-urea | 1-[(2,4-dic...)
Affinity DataEC50:  2.22E+3nMAssay Description:Name: Dose response of Retigabine-insensitive compounds that potentiate KCNQ2 potassium channel BioAssay Type: Confirmatory, Concentration-Response R...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetPotassium voltage-gated channel subfamily KQT member 2(Rattus norvegicus)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM65951(1-(3-fluorophenyl)-3-(5-fluoro-3-pyridinyl)urea;2,...)
Affinity DataEC50:  6.32E+3nMAssay Description:Name: Dose response of Retigabine-insensitive compounds that potentiate KCNQ2 potassium channel BioAssay Type: Confirmatory, Concentration-Response R...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetPotassium voltage-gated channel subfamily KQT member 2(Rattus norvegicus)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM65924(1-(4-methoxyphenyl)-3-(3-pyridinyl)urea | 1-(4-met...)
Affinity DataEC50:  2.03E+5nMAssay Description:Name: Dose response of Retigabine-insensitive compounds that potentiate KCNQ2 potassium channel BioAssay Type: Confirmatory, Concentration-Response R...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetPotassium voltage-gated channel subfamily KQT member 2(Rattus norvegicus)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM65925(1-(4-methylphenyl)-3-(3-pyridinyl)urea | 1-(4-meth...)
Affinity DataEC50:  1.28E+5nMAssay Description:Name: Dose response of Retigabine-insensitive compounds that potentiate KCNQ2 potassium channel BioAssay Type: Confirmatory, Concentration-Response R...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetPotassium voltage-gated channel subfamily KQT member 2(Rattus norvegicus)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM65926(1-(4-chlorophenyl)-3-(3-pyridinyl)urea | 1-(4-chlo...)
Affinity DataEC50:  6.85E+3nMAssay Description:Name: Dose response of Retigabine-insensitive compounds that potentiate KCNQ2 potassium channel BioAssay Type: Confirmatory, Concentration-Response R...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetPotassium voltage-gated channel subfamily KQT member 2(Rattus norvegicus)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM65927(1-phenyl-3-(3-pyridinyl)urea | 1-phenyl-3-(3-pyrid...)
Affinity DataEC50:  2.18E+4nMAssay Description:Name: Dose response of Retigabine-insensitive compounds that potentiate KCNQ2 potassium channel BioAssay Type: Confirmatory, Concentration-Response R...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetPotassium voltage-gated channel subfamily KQT member 2(Rattus norvegicus)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM65928(1-(3-chlorophenyl)-3-(3-pyridinyl)urea | 1-(3-chlo...)
Affinity DataEC50:  1.83E+4nMAssay Description:Name: Dose response of Retigabine-insensitive compounds that potentiate KCNQ2 potassium channel BioAssay Type: Confirmatory, Concentration-Response R...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetPotassium voltage-gated channel subfamily KQT member 2(Rattus norvegicus)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM65929(1-(3-fluorophenyl)-3-(3-pyridinyl)thiourea | 1-(3-...)
Affinity DataEC50:  4.19E+4nMAssay Description:Name: Dose response of Retigabine-insensitive compounds that potentiate KCNQ2 potassium channel BioAssay Type: Confirmatory, Concentration-Response R...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetPotassium voltage-gated channel subfamily KQT member 2(Rattus norvegicus)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM65930(1-(1,3-benzodioxol-5-yl)-3-(3-pyridinyl)urea | 1-(...)
Affinity DataEC50:  1.52E+5nMAssay Description:Name: Dose response of Retigabine-insensitive compounds that potentiate KCNQ2 potassium channel BioAssay Type: Confirmatory, Concentration-Response R...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetPotassium voltage-gated channel subfamily KQT member 2(Rattus norvegicus)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM65931(1-(3-chloranyl-4-fluoranyl-phenyl)-3-pyridin-3-yl-...)
Affinity DataEC50:  4.21E+3nMAssay Description:Name: Dose response of Retigabine-insensitive compounds that potentiate KCNQ2 potassium channel BioAssay Type: Confirmatory, Concentration-Response R...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetPotassium voltage-gated channel subfamily KQT member 2(Rattus norvegicus)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM65886(1-(4-phenoxyphenyl)-3-(3-pyridinyl)thiourea | 1-(4...)
Affinity DataEC50:  4.45E+3nMAssay Description:Name: Dose response of Retigabine-insensitive compounds that potentiate KCNQ2 potassium channel BioAssay Type: Confirmatory, Concentration-Response R...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetPotassium voltage-gated channel subfamily KQT member 2(Rattus norvegicus)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM65932(1-(4-butylphenyl)-3-(3-pyridinyl)thiourea | 1-(4-b...)
Affinity DataEC50:  2.68E+5nMAssay Description:Name: Dose response of Retigabine-insensitive compounds that potentiate KCNQ2 potassium channel BioAssay Type: Confirmatory, Concentration-Response R...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetPotassium voltage-gated channel subfamily KQT member 2(Rattus norvegicus)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM65933(1-(4-anilinophenyl)-3-(3-pyridinyl)thiourea | 1-(4...)
Affinity DataEC50:  1.10E+4nMAssay Description:Name: Dose response of Retigabine-insensitive compounds that potentiate KCNQ2 potassium channel BioAssay Type: Confirmatory, Concentration-Response R...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetPotassium voltage-gated channel subfamily KQT member 2(Rattus norvegicus)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM65934(1-(3-fluoranyl-4-methyl-phenyl)-3-pyridin-3-yl-ure...)
Affinity DataEC50:  9.14E+3nMAssay Description:Name: Dose response of Retigabine-insensitive compounds that potentiate KCNQ2 potassium channel BioAssay Type: Confirmatory, Concentration-Response R...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetPotassium voltage-gated channel subfamily KQT member 2(Rattus norvegicus)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM65935(1-(3-chlorophenyl)-3-(3-pyridinyl)thiourea | 1-(3-...)
Affinity DataEC50:  9.33E+3nMAssay Description:Name: Dose response of Retigabine-insensitive compounds that potentiate KCNQ2 potassium channel BioAssay Type: Confirmatory, Concentration-Response R...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetPotassium voltage-gated channel subfamily KQT member 2(Rattus norvegicus)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM65936(1-(3-pyridyl)-3-(4-sec-butylphenyl)thiourea | 1-(4...)
Affinity DataEC50:  1.26E+4nMAssay Description:Name: Dose response of Retigabine-insensitive compounds that potentiate KCNQ2 potassium channel BioAssay Type: Confirmatory, Concentration-Response R...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetPotassium voltage-gated channel subfamily KQT member 2(Rattus norvegicus)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM65937(1-(2,3-dimethylphenyl)-3-(3-pyridinyl)urea | 1-(2,...)
Affinity DataEC50:  1.60E+4nMAssay Description:Name: Dose response of Retigabine-insensitive compounds that potentiate KCNQ2 potassium channel BioAssay Type: Confirmatory, Concentration-Response R...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetPotassium voltage-gated channel subfamily KQT member 2(Rattus norvegicus)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM65938(1-(4-butylphenyl)-3-(3-pyridinyl)urea | 1-(4-butyl...)
Affinity DataEC50:  1.37E+4nMAssay Description:Name: Dose response of Retigabine-insensitive compounds that potentiate KCNQ2 potassium channel BioAssay Type: Confirmatory, Concentration-Response R...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetPotassium voltage-gated channel subfamily KQT member 2(Rattus norvegicus)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM65939(1-(4-ethoxyphenyl)-3-(3-pyridinyl)urea | 1-(4-etho...)
Affinity DataEC50:  1.43E+4nMAssay Description:Name: Dose response of Retigabine-insensitive compounds that potentiate KCNQ2 potassium channel BioAssay Type: Confirmatory, Concentration-Response R...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetPotassium voltage-gated channel subfamily KQT member 2(Rattus norvegicus)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM65940(1-(3,4-dimethylphenyl)-3-(3-pyridinyl)urea | 1-(3,...)
Affinity DataEC50:  1.35E+4nMAssay Description:Name: Dose response of Retigabine-insensitive compounds that potentiate KCNQ2 potassium channel BioAssay Type: Confirmatory, Concentration-Response R...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetPotassium voltage-gated channel subfamily KQT member 2(Rattus norvegicus)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM65941(1-(3,5-dimethylphenyl)-3-(3-pyridinyl)urea | 1-(3,...)
Affinity DataEC50:  1.07E+4nMAssay Description:Name: Dose response of Retigabine-insensitive compounds that potentiate KCNQ2 potassium channel BioAssay Type: Confirmatory, Concentration-Response R...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetPotassium voltage-gated channel subfamily KQT member 2(Rattus norvegicus)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM65942(1-(3-methylphenyl)-3-(3-pyridinyl)urea | 1-(3-meth...)
Affinity DataEC50:  1.68E+4nMAssay Description:Name: Dose response of Retigabine-insensitive compounds that potentiate KCNQ2 potassium channel BioAssay Type: Confirmatory, Concentration-Response R...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetPotassium voltage-gated channel subfamily KQT member 2(Rattus norvegicus)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM65943(1-(2,4-dichlorobenzyl)-3-(6-fluoro-3-pyridyl)urea ...)
Affinity DataEC50:  6.31E+3nMAssay Description:Name: Dose response of Retigabine-insensitive compounds that potentiate KCNQ2 potassium channel BioAssay Type: Confirmatory, Concentration-Response R...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PCBioAssay
TargetPotassium voltage-gated channel subfamily KQT member 2(Rattus norvegicus)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM65944(1-(6-chloranylpyridin-3-yl)-3-[(2,4-dichlorophenyl...)
Affinity DataEC50:  3.74E+3nMAssay Description:Name: Dose response of Retigabine-insensitive compounds that potentiate KCNQ2 potassium channel BioAssay Type: Confirmatory, Concentration-Response R...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PCBioAssay
TargetPotassium voltage-gated channel subfamily KQT member 2(Rattus norvegicus)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM65945(1-(2,4-dichlorobenzyl)-3-(5-fluoro-3-pyridyl)urea;...)
Affinity DataEC50:  8.64E+3nMAssay Description:Name: Dose response of Retigabine-insensitive compounds that potentiate KCNQ2 potassium channel BioAssay Type: Confirmatory, Concentration-Response R...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PCBioAssay
TargetPotassium voltage-gated channel subfamily KQT member 2(Rattus norvegicus)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM65946(1-(3-fluorophenyl)-3-(6-fluoro-3-pyridinyl)urea | ...)
Affinity DataEC50:  5.76E+3nMAssay Description:Name: Dose response of Retigabine-insensitive compounds that potentiate KCNQ2 potassium channel BioAssay Type: Confirmatory, Concentration-Response R...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetPotassium voltage-gated channel subfamily KQT member 2(Rattus norvegicus)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM65947(1-(6-chloranylpyridin-3-yl)-3-(3-fluorophenyl)urea...)
Affinity DataEC50:  2.81E+3nMAssay Description:Name: Dose response of Retigabine-insensitive compounds that potentiate KCNQ2 potassium channel BioAssay Type: Confirmatory, Concentration-Response R...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PCBioAssay
TargetPotassium voltage-gated channel subfamily KQT member 2(Rattus norvegicus)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM65948(1-(6-bromanyl-5-methyl-pyridin-3-yl)-3-(3-fluoroph...)
Affinity DataEC50:  6.61E+3nMAssay Description:Name: Dose response of Retigabine-insensitive compounds that potentiate KCNQ2 potassium channel BioAssay Type: Confirmatory, Concentration-Response R...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetPotassium voltage-gated channel subfamily KQT member 2(Rattus norvegicus)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM65949(1-(6-bromanylpyridin-3-yl)-3-(3-fluorophenyl)urea ...)
Affinity DataEC50:  4.04E+3nMAssay Description:Name: Dose response of Retigabine-insensitive compounds that potentiate KCNQ2 potassium channel BioAssay Type: Confirmatory, Concentration-Response R...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetPotassium voltage-gated channel subfamily KQT member 2(Rattus norvegicus)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM65950(1-(3-fluorophenyl)-3-(5-methyl-3-pyridinyl)urea;2,...)
Affinity DataEC50:  1.24E+4nMAssay Description:Name: Dose response of Retigabine-insensitive compounds that potentiate KCNQ2 potassium channel BioAssay Type: Confirmatory, Concentration-Response R...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetPotassium voltage-gated channel subfamily KQT member 2(Rattus norvegicus)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM65923(1-(3-Fluoro-phenyl)-3-pyridin-3-yl-urea | 1-(3-flu...)
Affinity DataEC50:  6.28E+3nMAssay Description:Name: Dose response of Retigabine-insensitive compounds that potentiate KCNQ2 potassium channel BioAssay Type: Confirmatory, Concentration-Response R...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay