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Found 40 Enz. Inhib. hit(s) with all data for entry = 50031393
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
National Organization For Drug Control & Research

Curated by ChEMBL
LigandPNGBDBM50312573(6-(2,4-Dihydroxyphenyl)-4-methyl-N-(3-nitrophenyl)...)
Affinity DataIC50:  300nMAssay Description:Inhibition of human recombinant CDK2/cyclin A expressed in baculovirus-infected insect Sf21 cells after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
National Organization For Drug Control & Research

Curated by ChEMBL
LigandPNGBDBM50312572(4-(2,4-Dihydroxyphenyl)-2-(5-(furan-2-ylmethylene)...)
Affinity DataIC50:  400nMAssay Description:Inhibition of human recombinant CDK2/cyclin A expressed in baculovirus-infected insect Sf21 cells after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
National Organization For Drug Control & Research

Curated by ChEMBL
LigandPNGBDBM50312575(CHEMBL1087791 | Rescovitine)
Affinity DataIC50:  500nMAssay Description:Inhibition of human recombinant CDK2/cyclin A expressed in baculovirus-infected insect Sf21 cells after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
National Organization For Drug Control & Research

Curated by ChEMBL
LigandPNGBDBM50312564(6-(2,4-dihydroxyphenyl)-4-methyl-2-(4-(N-(5-methyl...)
Affinity DataIC50:  900nMAssay Description:Inhibition of human recombinant CDK2/cyclin A expressed in baculovirus-infected insect Sf21 cells after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
National Organization For Drug Control & Research

Curated by ChEMBL
LigandPNGBDBM50312566(2-(benzylsulfonyl)-4-(2,4-dihydroxyphenyl)-6-methy...)
Affinity DataIC50:  900nMAssay Description:Inhibition of human recombinant CDK2/cyclin A expressed in baculovirus-infected insect Sf21 cells after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
National Organization For Drug Control & Research

Curated by ChEMBL
LigandPNGBDBM50312571(6-(2,4-Dihydroxyphenyl)-4-methyl-2-(3-methyl-5-oxo...)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of human recombinant CDK2/cyclin A expressed in baculovirus-infected insect Sf21 cells after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
National Organization For Drug Control & Research

Curated by ChEMBL
LigandPNGBDBM50312568(6-(2,4-Dihydroxyphenyl)-2-(2-(furan-2-ylmethylene)...)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of human recombinant CDK2/cyclin A expressed in baculovirus-infected insect Sf21 cells after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
National Organization For Drug Control & Research

Curated by ChEMBL
LigandPNGBDBM5718(2,6,9-Trisubstituted purine deriv. 26 | 2-{[6-(ben...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of human recombinant CDK2/cyclin A expressed in baculovirus-infected insect Sf21 cells after 10 minsMore data for this Ligand-Target Pair
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
National Organization For Drug Control & Research

Curated by ChEMBL
LigandPNGBDBM50312561(2-(2-Chloro-4-nitrophenylamino)-6-(2,4-dihydroxyph...)
Affinity DataIC50:  8.10E+3nMAssay Description:Inhibition of human recombinant CDK2/cyclin A expressed in baculovirus-infected insect Sf21 cells after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
National Organization For Drug Control & Research

Curated by ChEMBL
LigandPNGBDBM50312570(6-(2,4-Dihydroxyphenyl)-2-(4-(furan-2-ylmethylene)...)
Affinity DataIC50:  1.03E+4nMAssay Description:Inhibition of human recombinant CDK2/cyclin A expressed in baculovirus-infected insect Sf21 cells after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
National Organization For Drug Control & Research

Curated by ChEMBL
LigandPNGBDBM50312563(6-(2,4-dihydroxyphenyl)-2-(4-(N-(4,6-dimethylpyrim...)
Affinity DataIC50:  1.15E+4nMAssay Description:Inhibition of human recombinant CDK2/cyclin A expressed in baculovirus-infected insect Sf21 cells after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
National Organization For Drug Control & Research

Curated by ChEMBL
LigandPNGBDBM50312569(6-(2,4-Dihydroxyphenyl)-4-methyl-N-(3-nitrophenyl)...)
Affinity DataIC50:  2.29E+4nMAssay Description:Inhibition of human recombinant CDK2/cyclin A expressed in baculovirus-infected insect Sf21 cells after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Organization For Drug Control & Research

Curated by ChEMBL
LigandPNGBDBM50312558(2-(Benzylamino)-6-(2,4-dihydroxyphenyl)-4-methyl-N...)
Affinity DataIC50:  2.35E+4nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
National Organization For Drug Control & Research

Curated by ChEMBL
LigandPNGBDBM50312577(2-(Benzylthio)-6-(2,4-dihydroxyphenyl)-4-methyl-N-...)
Affinity DataIC50:  2.46E+4nMAssay Description:Inhibition of human recombinant CDK2/cyclin A expressed in baculovirus-infected insect Sf21 cells after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
National Organization For Drug Control & Research

Curated by ChEMBL
LigandPNGBDBM50312576(2-(Benzylthio)-6-(2,4-dihydroxyphenyl)-4-methyl-N-...)
Affinity DataIC50:  2.54E+4nMAssay Description:Inhibition of human recombinant CDK2/cyclin A expressed in baculovirus-infected insect Sf21 cells after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
National Organization For Drug Control & Research

Curated by ChEMBL
LigandPNGBDBM50312574(2-(5-Benzylidene-4-oxo-2-thioxothiazolidin-3-ylami...)
Affinity DataIC50:  2.82E+4nMAssay Description:Inhibition of human recombinant CDK2/cyclin A expressed in baculovirus-infected insect Sf21 cells after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
National Organization For Drug Control & Research

Curated by ChEMBL
LigandPNGBDBM50312559(2-(2-Chloro-4-nitrophenylamino)-6-(2,4-dihydroxyph...)
Affinity DataIC50:  4.49E+4nMAssay Description:Inhibition of human recombinant CDK2/cyclin A expressed in baculovirus-infected insect Sf21 cells after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
National Organization For Drug Control & Research

Curated by ChEMBL
LigandPNGBDBM50312560(2-(Benzylamino)-6-(2,4-dihydroxyphenyl)-4-methyl-N...)
Affinity DataIC50:  4.68E+4nMAssay Description:Inhibition of human recombinant CDK2/cyclin A expressed in baculovirus-infected insect Sf21 cells after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Organization For Drug Control & Research

Curated by ChEMBL
LigandPNGBDBM50312567(6-(2,4-Dihydroxyphenyl)-2-hydrazinyl-4-methyl-N-(3...)
Affinity DataIC50:  4.79E+4nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
National Organization For Drug Control & Research

Curated by ChEMBL
LigandPNGBDBM50312565(2-(benzylsulfonyl)-4-(2,4-dihydroxyphenyl)-6-methy...)
Affinity DataIC50:  4.83E+4nMAssay Description:Inhibition of human recombinant CDK2/cyclin A expressed in baculovirus-infected insect Sf21 cells after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Organization For Drug Control & Research

Curated by ChEMBL
LigandPNGBDBM50312577(2-(Benzylthio)-6-(2,4-dihydroxyphenyl)-4-methyl-N-...)
Affinity DataIC50:  5.56E+4nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
National Organization For Drug Control & Research

Curated by ChEMBL
LigandPNGBDBM50312562(6-(2,4-dihydroxyphenyl)-4-methyl-N-(3-nitrophenyl)...)
Affinity DataIC50:  5.75E+4nMAssay Description:Inhibition of human recombinant CDK2/cyclin A expressed in baculovirus-infected insect Sf21 cells after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Organization For Drug Control & Research

Curated by ChEMBL
LigandPNGBDBM50312559(2-(2-Chloro-4-nitrophenylamino)-6-(2,4-dihydroxyph...)
Affinity DataIC50:  6.09E+4nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Organization For Drug Control & Research

Curated by ChEMBL
LigandPNGBDBM50312563(6-(2,4-dihydroxyphenyl)-2-(4-(N-(4,6-dimethylpyrim...)
Affinity DataIC50:  7.98E+4nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Organization For Drug Control & Research

Curated by ChEMBL
LigandPNGBDBM50312573(6-(2,4-Dihydroxyphenyl)-4-methyl-N-(3-nitrophenyl)...)
Affinity DataIC50:  8.06E+4nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Organization For Drug Control & Research

Curated by ChEMBL
LigandPNGBDBM50312562(6-(2,4-dihydroxyphenyl)-4-methyl-N-(3-nitrophenyl)...)
Affinity DataIC50:  8.83E+4nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Organization For Drug Control & Research

Curated by ChEMBL
LigandPNGBDBM50312576(2-(Benzylthio)-6-(2,4-dihydroxyphenyl)-4-methyl-N-...)
Affinity DataIC50:  9.35E+4nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Organization For Drug Control & Research

Curated by ChEMBL
LigandPNGBDBM50312572(4-(2,4-Dihydroxyphenyl)-2-(5-(furan-2-ylmethylene)...)
Affinity DataIC50:  9.93E+4nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Organization For Drug Control & Research

Curated by ChEMBL
LigandPNGBDBM50312565(2-(benzylsulfonyl)-4-(2,4-dihydroxyphenyl)-6-methy...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Organization For Drug Control & Research

Curated by ChEMBL
LigandPNGBDBM50312566(2-(benzylsulfonyl)-4-(2,4-dihydroxyphenyl)-6-methy...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Organization For Drug Control & Research

Curated by ChEMBL
LigandPNGBDBM50312574(2-(5-Benzylidene-4-oxo-2-thioxothiazolidin-3-ylami...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Organization For Drug Control & Research

Curated by ChEMBL
LigandPNGBDBM50312568(6-(2,4-Dihydroxyphenyl)-2-(2-(furan-2-ylmethylene)...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Organization For Drug Control & Research

Curated by ChEMBL
LigandPNGBDBM50312569(6-(2,4-Dihydroxyphenyl)-4-methyl-N-(3-nitrophenyl)...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Organization For Drug Control & Research

Curated by ChEMBL
LigandPNGBDBM50312570(6-(2,4-Dihydroxyphenyl)-2-(4-(furan-2-ylmethylene)...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Organization For Drug Control & Research

Curated by ChEMBL
LigandPNGBDBM50312571(6-(2,4-Dihydroxyphenyl)-4-methyl-2-(3-methyl-5-oxo...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
National Organization For Drug Control & Research

Curated by ChEMBL
LigandPNGBDBM50312558(2-(Benzylamino)-6-(2,4-dihydroxyphenyl)-4-methyl-N...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant CDK2/cyclin A expressed in baculovirus-infected insect Sf21 cells after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Organization For Drug Control & Research

Curated by ChEMBL
LigandPNGBDBM50312564(6-(2,4-dihydroxyphenyl)-4-methyl-2-(4-(N-(5-methyl...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
National Organization For Drug Control & Research

Curated by ChEMBL
LigandPNGBDBM50312567(6-(2,4-Dihydroxyphenyl)-2-hydrazinyl-4-methyl-N-(3...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant CDK2/cyclin A expressed in baculovirus-infected insect Sf21 cells after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Organization For Drug Control & Research

Curated by ChEMBL
LigandPNGBDBM50312560(2-(Benzylamino)-6-(2,4-dihydroxyphenyl)-4-methyl-N...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Organization For Drug Control & Research

Curated by ChEMBL
LigandPNGBDBM50312561(2-(2-Chloro-4-nitrophenylamino)-6-(2,4-dihydroxyph...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed