Compile Data Set for Download or QSAR
maximum 50k data
Found 114 Enz. Inhib. hit(s) with all data for entry = 50031820
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50319933((1S,4S)-2,2-dimethyl-5-(6-phenylpyridazin-3-yl)-5-...)
Affinity DataKi:  0.0660nMAssay Description:Displacement of [3H]A585539 from alpha7 nACHR in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50319964(5-(6-((1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]hept...)
Affinity DataKi:  0.200nMAssay Description:Displacement of [3H]A585539 from alpha7 nACHR in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50319928((1R,4R)-2-(6-chloropyridazin-3-yl)-2,5-diazabicycl...)
Affinity DataKi:  0.200nMAssay Description:Displacement of [3H]cytisine from alpha4beta2 nACHR in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50319963(5-(6-((1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]hept...)
Affinity DataKi:  0.300nMAssay Description:Displacement of [3H]A585539 from alpha7 nACHR in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50319944(2-methyl-5-(6-((1S,4S)-5-methyl-2,5-diazabicyclo[2...)
Affinity DataKi:  0.300nMAssay Description:Displacement of [3H]A585539 from alpha7 nACHR in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50319940(5-(6-((1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]hept...)
Affinity DataKi:  0.400nMAssay Description:Displacement of [3H]A585539 from alpha7 nACHR in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50319962((1S,4S)-2-(5-(benzo[b]thiophen-5-yl)pyridin-2-yl)-...)
Affinity DataKi:  0.550nMAssay Description:Displacement of [3H]dofetidile from human ERG by whole-cell patch clampMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50319955((1S,4S)-2-(5-(benzo[b]thiophen-5-yl)pyrimidin-2-yl...)
Affinity DataKi:  0.560nMAssay Description:Displacement of [3H]dofetidile from human ERG by whole-cell patch clampMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50319939(5-(6-((1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]hept...)
Affinity DataKi:  0.900nMAssay Description:Displacement of [3H]A585539 from alpha7 nACHR in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50319949(5-(5-((1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]hept...)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]A585539 from alpha7 nACHR in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50319957(5-(2-((1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]hept...)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]A585539 from alpha7 nACHR in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50319947((1S,4S)-2-(5-(benzo[b]thiophen-5-yl)pyrazin-2-yl)-...)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]dofetidile from human ERG by whole-cell patch clampMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50319954((1S,4S)-2-(5-(benzofuran-5-yl)pyrimidin-2-yl)-5-me...)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]dofetidile from human ERG by whole-cell patch clampMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50319938((1S,4S)-2-(6-(benzo[b]thiophen-5-yl)pyridazin-3-yl...)
Affinity DataKi:  1.80nMAssay Description:Displacement of [3H]dofetidile from human ERG by whole-cell patch clampMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50319958(5-(2-((1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]hept...)
Affinity DataKi:  1.85nMAssay Description:Displacement of [3H]dofetidile from human ERG by whole-cell patch clampMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50319950(5-(5-((1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]hept...)
Affinity DataKi:  1.90nMAssay Description:Displacement of [3H]dofetidile from human ERG by whole-cell patch clampMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50319965(5-(6-((1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]hept...)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]dofetidile from human ERG by whole-cell patch clampMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50319941(5-(6-((1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]hept...)
Affinity DataKi:  2.10nMAssay Description:Displacement of [3H]A585539 from alpha7 nACHR in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50319935((1R,4R)-2,2-dimethyl-5-(6-phenylpyridazin-3-yl)-5-...)
Affinity DataKi:  2.20nMAssay Description:Displacement of [3H]A585539 from alpha7 nACHR in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50319941(5-(6-((1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]hept...)
Affinity DataKi:  2.20nMAssay Description:Displacement of [3H]dofetidile from human ERG by whole-cell patch clampMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50319961((1S,4S)-2-(5-(benzofuran-5-yl)pyridin-2-yl)-5-meth...)
Affinity DataKi:  2.70nMAssay Description:Displacement of [3H]dofetidile from human ERG by whole-cell patch clampMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50319967(6-(6-((1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]hept...)
Affinity DataKi:  2.90nMAssay Description:Displacement of [3H]dofetidile from human ERG by whole-cell patch clampMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50319962((1S,4S)-2-(5-(benzo[b]thiophen-5-yl)pyridin-2-yl)-...)
Affinity DataKi:  2.90nMAssay Description:Displacement of [3H]A585539 from alpha7 nACHR in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50319965(5-(6-((1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]hept...)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]A585539 from alpha7 nACHR in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50319960((1S,4S)-2-methyl-5-(5-phenylpyridin-2-yl)-2,5-diaz...)
Affinity DataKi:  3.10nMAssay Description:Displacement of [3H]A585539 from alpha7 nACHR in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50319938((1S,4S)-2-(6-(benzo[b]thiophen-5-yl)pyridazin-3-yl...)
Affinity DataKi:  3.10nMAssay Description:Displacement of [3H]A585539 from alpha7 nACHR in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50319931((1S,4S)-5-(6-chloropyridazin-3-yl)-2,2-dimethyl-5-...)
Affinity DataKi:  4.30nMAssay Description:Displacement of [3H]cytisine from alpha4beta2 nACHR in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50319957(5-(2-((1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]hept...)
Affinity DataKi:  4.30nMAssay Description:Displacement of [3H]dofetidile from human ERG by whole-cell patch clampMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50319961((1S,4S)-2-(5-(benzofuran-5-yl)pyridin-2-yl)-5-meth...)
Affinity DataKi:  4.40nMAssay Description:Displacement of [3H]A585539 from alpha7 nACHR in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50319946((1S,4S)-2-(5-(benzofuran-5-yl)pyrazin-2-yl)-5-meth...)
Affinity DataKi:  5.30nMAssay Description:Displacement of [3H]dofetidile from human ERG by whole-cell patch clampMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50319967(6-(6-((1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]hept...)
Affinity DataKi:  5.40nMAssay Description:Displacement of [3H]A585539 from alpha7 nACHR in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50319927((1S,4S)-2-(6-chloropyridazin-3-yl)-2,5-diazabicycl...)
Affinity DataKi:  6nMAssay Description:Displacement of [3H]cytisine from alpha4beta2 nACHR in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50319948(5-(5-((1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]hept...)
Affinity DataKi:  6.30nMAssay Description:Displacement of [3H]A585539 from alpha7 nACHR in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50319943(6-(6-((1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]hept...)
Affinity DataKi:  7nMAssay Description:Displacement of [3H]A585539 from alpha7 nACHR in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50319956(5-(2-((1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]hept...)
Affinity DataKi:  7.60nMAssay Description:Displacement of [3H]A585539 from alpha7 nACHR in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50319937((1S,4S)-2-(6-(benzofuran-5-yl)pyridazin-3-yl)-5-me...)
Affinity DataKi:  8.80nMAssay Description:Displacement of [3H]dofetidile from human ERG by whole-cell patch clampMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50319952(6-(5-((1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]hept...)
Affinity DataKi:  9nMAssay Description:Displacement of [3H]dofetidile from human ERG by whole-cell patch clampMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50319936((1S,4S)-2-methyl-5-(6-phenylpyridazin-3-yl)-2,5-di...)
Affinity DataKi:  9.30nMAssay Description:Displacement of [3H]A585539 from alpha7 nACHR in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50319966(4-(6-((1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]hept...)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]A585539 from alpha7 nACHR in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50319960((1S,4S)-2-methyl-5-(5-phenylpyridin-2-yl)-2,5-diaz...)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]dofetidile from human ERG by whole-cell patch clampMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50319932((1S,4S)-2-(6-phenylpyridazin-3-yl)-2,5-diazabicycl...)
Affinity DataKi:  10.1nMAssay Description:Displacement of [3H]A585539 from alpha7 nACHR in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50319964(5-(6-((1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]hept...)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]dofetidile from human ERG by whole-cell patch clampMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50319943(6-(6-((1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]hept...)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]dofetidile from human ERG by whole-cell patch clampMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50319944(2-methyl-5-(6-((1S,4S)-5-methyl-2,5-diazabicyclo[2...)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]dofetidile from human ERG by whole-cell patch clampMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50319942(4-(6-((1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]hept...)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]A585539 from alpha7 nACHR in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50319959(4-(2-((1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]hept...)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]dofetidile from human ERG by whole-cell patch clampMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50319949(5-(5-((1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]hept...)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]dofetidile from human ERG by whole-cell patch clampMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50319937((1S,4S)-2-(6-(benzofuran-5-yl)pyridazin-3-yl)-5-me...)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]A585539 from alpha7 nACHR in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50319958(5-(2-((1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]hept...)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]A585539 from alpha7 nACHR in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50319950(5-(5-((1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]hept...)
Affinity DataKi:  17nMAssay Description:Displacement of [3H]A585539 from alpha7 nACHR in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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