Compile Data Set for Download or QSAR
maximum 50k data
Found 25 Enz. Inhib. hit(s) with all data for entry = 50037711
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50098106(CHEMBL24259 | PHENYLSULFAMATE | Sulfamic acid phen...)
Affinity DataKi:  36nMAssay Description:Inhibition of human CA2 by carbon dioxide hydrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50124157(4-nitrophenylsulfamide | CHEMBL168778 | N-(4-nitro...)
Affinity DataKi:  892nMAssay Description:Inhibition of human CA2 by carbon dioxide hydrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50188393((2,2-dimethyl-1,3-dioxolan-4-yl)methyl sulfamate |...)
Affinity DataKi:  1.02E+3nMAssay Description:Inhibition of human CA2 by carbon dioxide hydrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50124157(4-nitrophenylsulfamide | CHEMBL168778 | N-(4-nitro...)
Affinity DataKi:  1.74E+3nMAssay Description:Inhibition of human CA2 by 4-nitrophenyl acetate hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50124170(CHEMBL168514 | N-phenylsulfamide | PHENYLSULFAMIDE)
Affinity DataKi:  7.96E+3nMAssay Description:Inhibition of human CA2 by carbon dioxide hydrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50124170(CHEMBL168514 | N-phenylsulfamide | PHENYLSULFAMIDE)
Affinity DataKi:  8.02E+3nMAssay Description:Inhibition of human CA2 by 4-nitrophenyl acetate hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50124171(4-methoxyphenylsulfamide | CHEMBL165878 | N-(4-met...)
Affinity DataKi:  1.44E+4nMAssay Description:Inhibition of human CA2 by carbon dioxide hydrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50124171(4-methoxyphenylsulfamide | CHEMBL165878 | N-(4-met...)
Affinity DataKi:  1.88E+4nMAssay Description:Inhibition of human CA2 by 4-nitrophenyl acetate hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50188392(CHEMBL378292 | N-(2,2-dimethyl-1,3-dioxolan-4-ylme...)
Affinity DataKi:  4.08E+5nMAssay Description:Inhibition of human CA2 by carbon dioxide hydrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50188393((2,2-dimethyl-1,3-dioxolan-4-yl)methyl sulfamate |...)
Affinity DataKd:  2.00E+3nMAssay Description:Binding affinity to human CA2 by ThermoFluor assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50124157(4-nitrophenylsulfamide | CHEMBL168778 | N-(4-nitro...)
Affinity DataKd:  1.00E+3nMpH: 7.5Assay Description:Binding affinity to human CA2 in presence of sodium sulfate and ANS at pH 7.5 by ThermoFluor assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50124157(4-nitrophenylsulfamide | CHEMBL168778 | N-(4-nitro...)
Affinity DataKd:  1.50E+3nMpH: 7.4Assay Description:Binding affinity to human CA2 at pH 7.4 by ThermoFluor assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50163319(CHEMBL175644 | N-(3,4-dihydro-2H-chromen-2-ylmethy...)
Affinity DataKd:  1.00E+4nMAssay Description:Binding affinity to human CA2 by ThermoFluor assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50163317((3,4-dihydro-2H-chromen-2-yl)methyl sulfamate | CH...)
Affinity DataKd:  140nMAssay Description:Binding affinity to human CA2 by ThermoFluor assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50098106(CHEMBL24259 | PHENYLSULFAMATE | Sulfamic acid phen...)
Affinity DataKd:  110nMAssay Description:Binding affinity to human CA2 by ThermoFluor assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50124171(4-methoxyphenylsulfamide | CHEMBL165878 | N-(4-met...)
Affinity DataKd:  2.65E+3nMpH: 7.5Assay Description:Binding affinity to human CA2 in presence of sodium sulfate and ANS at pH 7.5 by ThermoFluor assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM10887(Sulfamate 7 | Topiramate (TPM) | US11535599, Examp...)
Affinity DataKd:  290nMAssay Description:Binding affinity to human CA2 by ThermoFluor assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50124170(CHEMBL168514 | N-phenylsulfamide | PHENYLSULFAMIDE)
Affinity DataKd:  3.75E+3nMpH: 7.4Assay Description:Binding affinity to human CA2 at pH 7.4 by ThermoFluor assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50124170(CHEMBL168514 | N-phenylsulfamide | PHENYLSULFAMIDE)
Affinity DataKd:  2.00E+3nMpH: 7.5Assay Description:Binding affinity to human CA2 in presence of sodium sulfate and ANS at pH 7.5 by ThermoFluor assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50124170(CHEMBL168514 | N-phenylsulfamide | PHENYLSULFAMIDE)
Affinity DataKd:  4.55E+3nMAssay Description:Binding affinity to human CA2 by ThermoFluor assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM13055(CHEMBL283695 | Compound 8 | Topiramate Sulfamide A...)
Affinity DataKd:  2.50E+4nMAssay Description:Binding affinity to human CA2 by ThermoFluor assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50163316(CHEMBL177425 | N-{[(3aR,5aS,8aS,8bS)-7,7-dimethyl-...)
Affinity DataKd:  1.25E+4nMAssay Description:Binding affinity to human CA2 by ThermoFluor assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50124171(4-methoxyphenylsulfamide | CHEMBL165878 | N-(4-met...)
Affinity DataKd:  5.00E+3nMpH: 7.4Assay Description:Binding affinity to human CA2 at pH 7.4 by ThermoFluor assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50188392(CHEMBL378292 | N-(2,2-dimethyl-1,3-dioxolan-4-ylme...)
Affinity DataKd:  5.00E+4nMAssay Description:Binding affinity to human CA2 by ThermoFluor assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM13057(CHEMBL417656 | Compound 9 | Cyclic Sulfate Analogu...)
Affinity DataKd:  10nMAssay Description:Binding affinity to human CA2 by ThermoFluor assayMore data for this Ligand-Target Pair