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Found 6 Enz. Inhib. hit(s) with all data for entry = 50038457
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
The Chinese University Of Hong Kong

Curated by ChEMBL
LigandPNGBDBM26658(2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxy-1-benzopy...)
Affinity DataKi:  5.74E+3nMAssay Description:Inhibition of human URAT1-mediated urate uptake in HEK293 cells by competitive inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
The Chinese University Of Hong Kong

Curated by ChEMBL
LigandPNGBDBM50158460((3,5-dibromo-4-hydroxyphenyl)(2-ethyl-1-benzofuran...)
Affinity DataIC50:  300nMAssay Description:Inhibition of human URAT1-mediated urate uptake in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
The Chinese University Of Hong Kong

Curated by ChEMBL
LigandPNGBDBM26658(2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxy-1-benzopy...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of human URAT1-mediated urate uptake in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 22 member 12(Rattus norvegicus)
The Chinese University Of Hong Kong

Curated by ChEMBL
LigandPNGBDBM26658(2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxy-1-benzopy...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of human URAT1-mediated urate uptake in rat renal brush border membrane vesiclesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
The Chinese University Of Hong Kong

Curated by ChEMBL
LigandPNGBDBM50206509(4-Dipropylsulfamoyl-benzoic acid | 4-Dipropylsulfa...)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition of human URAT1-mediated urate uptake in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSolute carrier family 22 member 12(Homo sapiens (Human))
The Chinese University Of Hong Kong

Curated by ChEMBL
LigandPNGBDBM50026604(1,2-Diphenyl-3,5-dioxo-4-(2-phenylsulfinylethyl)py...)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of human URAT1-mediated urate uptake in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed