Compile Data Set for Download or QSAR
maximum 50k data
Found 50 Enz. Inhib. hit(s) with all data for entry = 50037244
TargetProtein kinase C alpha type(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM2681(3-{1-[3-(dimethylamino)propyl]-1H-indol-3-yl}-4-(1...)
Affinity DataIC50:  20nMAssay Description:Inhibition of Protein kinase C alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM3175(3-[1-[3-(Amidinothio)propyl]-3-indolyl]-4-(1-methy...)
Affinity DataIC50:  33nMAssay Description:Inhibition of Protein kinase C alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM13336(4-[4-(4-fluorophenyl)-2-(4-methanesulfinylphenyl)-...)
Affinity DataIC50:  50nMAssay Description:Inhibition of Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase N2(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM14029((R)-TRANS-4-(1-AMINOETHYL)-N-(4-PYRIDYL) CYCLOHEXA...)
Affinity DataIC50:  600nMAssay Description:Inhibition of Protein kinase C related kinase 2 (PRK2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM14029((R)-TRANS-4-(1-AMINOETHYL)-N-(4-PYRIDYL) CYCLOHEXA...)
Affinity DataIC50:  700nMAssay Description:Inhibition of Protein kinase ROCK2 (ROCKII)More data for this Ligand-Target Pair
TargetMalate dehydrogenase(Thermus thermophilus)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50126829((E)-1-(6-(3-acetyl-2,4,6-trihydroxy-5-methylbenzyl...)
Affinity DataIC50:  700nMAssay Description:Inhibitory activity against malate dehydrogenase (MDH) from Thermus flavusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50108771(2'-amino-3'-methoxyflavone | 2-(2-Amino-3-methoxy-...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibitory activity against Prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50336799(5,5',5''-[1,3,6-naphthalenetriyltris(sulfonylimino...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibitory activity against DNA-DNA dependent protein kinase (DNA-PK)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase N1(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM14027(5-(1,4-diazepan-1-ylsulfonyl)isoquinoline | 5-(1,4...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of Protein kinase C related kinase 1 (PRK1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMyosin light chain kinase, smooth muscle(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM15234((1R,3R,5S,9R,18S)-18-(methoxymethyl)-1,5-dimethyl-...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of Smooth muscle myosin light chain kinase (mMLCK)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 5(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50126829((E)-1-(6-(3-acetyl-2,4,6-trihydroxy-5-methylbenzyl...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of p38-regulated activated kinase (PRAK)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM14027(5-(1,4-diazepan-1-ylsulfonyl)isoquinoline | 5-(1,4...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of Protein kinase ROCK2 (ROCKII)More data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50108771(2'-amino-3'-methoxyflavone | 2-(2-Amino-3-methoxy-...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of Mitogen activated protein kinase kinase 1 (MKK1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM13336(4-[4-(4-fluorophenyl)-2-(4-methanesulfinylphenyl)-...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibitory activity against Prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50023867(Indirubin)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of Cyclin-dependent kinase 2 (CDK2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetO94806/P05129/P05771/P17252/P24723/P41743/Q02156/Q04759/Q05513/Q05655/Q15139(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM2581(3,13,23-triazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^...)
Affinity DataIC50:  2.45E+3nMAssay Description:Inhibition of Protein kinase CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C delta type(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50126829((E)-1-(6-(3-acetyl-2,4,6-trihydroxy-5-methylbenzyl...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of Protein kinase C delta (PKCdelta)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50027095(CHEMBL36450 | SC-68376)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalate dehydrogenase(Thermus thermophilus)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chrome...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibitory activity against malate dehydrogenase (MDH) from Thermus flavusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalate dehydrogenase(Thermus thermophilus)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM2581(3,13,23-triazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibitory activity against malate dehydrogenase (MDH) from Thermus flavusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen B(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM2581(3,13,23-triazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibitory activity against Chymotrypsinogen from Thermus flavusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen B(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50111589(2-[(3,5-diiodo-4-oxidophenyl)(3,5-diiodo-4-oxocycl...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibitory activity against Chymotrypsinogen from Thermus flavusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50072147((2Z,3Z)-2,3-bis(amino(2-aminophenylthio)methylene)...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of Mitogen activated protein kinase kinase 1 (MKK1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetChymotrypsinogen B(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50111604(3-[(4-Phenoxy-phenylamino)-methylene]-3H-isobenzof...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibitory activity against Chymotrypsinogen from Thermus flavusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50023867(Indirubin)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of Src tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen B(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM3175(3-[1-[3-(Amidinothio)propyl]-3-indolyl]-4-(1-methy...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibitory activity against Chymotrypsinogen from Thermus flavusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen B(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50126829((E)-1-(6-(3-acetyl-2,4,6-trihydroxy-5-methylbenzyl...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibitory activity against Chymotrypsinogen from Thermus flavusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen B(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50111585(4-(4-Bromo-phenylazo)-phenol | 4-bromophenylazophe...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibitory activity against Chymotrypsinogen from Thermus flavusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalate dehydrogenase(Thermus thermophilus)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50111591(4-[2-(2,4-Difluoro-phenylamino)-thiazol-4-yl]-benz...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibitory activity against malate dehydrogenase (MDH) from Thermus flavusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalate dehydrogenase(Thermus thermophilus)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50111589(2-[(3,5-diiodo-4-oxidophenyl)(3,5-diiodo-4-oxocycl...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibitory activity against malate dehydrogenase (MDH) from Thermus flavusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha/beta/gamma(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM2581(3,13,23-triazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^...)
Affinity DataIC50:  2.57E+4nMAssay Description:Inhibition of Protein kinase AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50310357(CHEMBL599552 | indigo)
Affinity DataIC50:  2.80E+4nMAssay Description:Inhibition of Src tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalate dehydrogenase(Thermus thermophilus)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50023867(Indirubin)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibitory activity against malate dehydrogenase (MDH) from Thermus flavusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalate dehydrogenase(Thermus thermophilus)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50111585(4-(4-Bromo-phenylazo)-phenol | 4-bromophenylazophe...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibitory activity against malate dehydrogenase (MDH) from Thermus flavusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalate dehydrogenase(Thermus thermophilus)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM3175(3-[1-[3-(Amidinothio)propyl]-3-indolyl]-4-(1-methy...)
Affinity DataIC50:  4.50E+4nMAssay Description:Inhibitory activity against malate dehydrogenase (MDH) from Thermus flavusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 5(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50072147((2Z,3Z)-2,3-bis(amino(2-aminophenylthio)methylene)...)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition of p38-regulated activated kinase (Protein kinase PRAK)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalate dehydrogenase(Thermus thermophilus)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50126827(4-(1-Hydroxy-naphthalen-2-ylazo)-naphthalene-1-sul...)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibitory activity against malate dehydrogenase (MDH) from Thermus flavusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalate dehydrogenase(Thermus thermophilus)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50310357(CHEMBL599552 | indigo)
Affinity DataIC50:  6.00E+4nMAssay Description:Inhibitory activity against malate dehydrogenase (MDH) from Thermus flavusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50310357(CHEMBL599552 | indigo)
Affinity DataIC50:  7.00E+4nMAssay Description:Inhibition of Cyclin-dependent kinase 2 (CDK2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen B(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50126827(4-(1-Hydroxy-naphthalen-2-ylazo)-naphthalene-1-sul...)
Affinity DataIC50:  9.00E+4nMAssay Description:Inhibitory activity against Chymotrypsinogen from Thermus flavusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen B(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50310357(CHEMBL599552 | indigo)
Affinity DataIC50:  9.00E+4nMAssay Description:Inhibitory activity against Chymotrypsinogen from Thermus flavusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen B(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50111591(4-[2-(2,4-Difluoro-phenylamino)-thiazol-4-yl]-benz...)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibitory activity against Chymotrypsinogen from Thermus flavusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen B(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chrome...)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibitory activity against Chymotrypsinogen from Thermus flavusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen B(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50023867(Indirubin)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibitory activity against Chymotrypsinogen from Thermus flavusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalate dehydrogenase(Thermus thermophilus)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50072147((2Z,3Z)-2,3-bis(amino(2-aminophenylthio)methylene)...)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibitory activity against malate dehydrogenase (MDH) from Thermus flavusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen B(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50072147((2Z,3Z)-2,3-bis(amino(2-aminophenylthio)methylene)...)
Affinity DataIC50:  1.20E+5nMAssay Description:Inhibitory activity against Chymotrypsinogen from Thermus flavusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalate dehydrogenase(Thermus thermophilus)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50111604(3-[(4-Phenoxy-phenylamino)-methylene]-3H-isobenzof...)
Affinity DataIC50:  1.20E+5nMAssay Description:Inhibitory activity against malate dehydrogenase (MDH) from Thermus flavusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen B(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM2681(3-{1-[3-(dimethylamino)propyl]-1H-indol-3-yl}-4-(1...)
Affinity DataIC50:  2.00E+5nMAssay Description:Inhibitory activity against Chymotrypsinogen from Thermus flavusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalate dehydrogenase(Thermus thermophilus)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM2681(3-{1-[3-(dimethylamino)propyl]-1H-indol-3-yl}-4-(1...)
Affinity DataIC50: >4.00E+5nMAssay Description:Inhibitory activity against malate dehydrogenase (MDH) from Thermus flavusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed