Found 6 Enz. Inhib. hit(s) with all data for entry = 50004660 Target2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase(Escherichia coli (strain K12))
National Cancer Institute
Curated by ChEMBL
National Cancer Institute
Curated by ChEMBL
Affinity DataIC50: 440nMAssay Description:Inhibition of Escherichia coli HPPK using [alpha-33P]ATP after 30 minsMore data for this Ligand-Target Pair
Target2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase(Escherichia coli (strain K12))
National Cancer Institute
Curated by ChEMBL
National Cancer Institute
Curated by ChEMBL
Affinity DataIC50: 3.16E+3nMAssay Description:Inhibition of Escherichia coli HPPK using [alpha-33P]ATP after 30 minsMore data for this Ligand-Target Pair
3D Structure (crystal)Target2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase(Escherichia coli (strain K12))
National Cancer Institute
Curated by ChEMBL
National Cancer Institute
Curated by ChEMBL
Affinity DataIC50: 9.53E+3nMAssay Description:Inhibition of Escherichia coli HPPK using [alpha-33P]ATP after 30 minsMore data for this Ligand-Target Pair
Target2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase(Escherichia coli (strain K12))
National Cancer Institute
Curated by ChEMBL
National Cancer Institute
Curated by ChEMBL
Affinity DataKd: 4.16E+3nMAssay Description:Binding affinity to Escherichia coli HPPK at pH 8.3 by fluorometric titrationMore data for this Ligand-Target Pair
Target2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase(Escherichia coli (strain K12))
National Cancer Institute
Curated by ChEMBL
National Cancer Institute
Curated by ChEMBL
Affinity DataKd: 470nMAssay Description:Binding affinity to Escherichia coli HPPKMore data for this Ligand-Target Pair
Target2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase(Escherichia coli (strain K12))
National Cancer Institute
Curated by ChEMBL
National Cancer Institute
Curated by ChEMBL
Affinity DataKd: 2.55E+3nMAssay Description:Binding affinity to Escherichia coli HPPKMore data for this Ligand-Target Pair
