Compile Data Set for Download or QSAR
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Found 17 Enz. Inhib. hit(s) with all data for entry = 50006092
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50496868(CHEMBL3220345)
Affinity DataIC50:  240nMAssay Description:Displacement of [125I]-iodoarylazidoprazosin from human P-gp expressed in baculovirus-infected insect Sf9 cells incubated for 10 mins followed by UV ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50496870(CHEMBL3220346)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of P-gp in human CMEC/D3 cells assessed as inhibition of NBD-Aba efflux after 30 mins by flow cytometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50496870(CHEMBL3220346)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of P-gp overexpressed in human 12D7-MDR cells assessed as inhibition of calcein-AM efflux after 30 mins by flow cytometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50496870(CHEMBL3220346)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of P-gp overexpressed in human 12D7-MDR cells assessed as inhibition of NBD-Aba efflux after 30 mins by flow cytometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50496868(CHEMBL3220345)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of P-gp overexpressed in human 12D7-MDR cells assessed as inhibition of NBD-Aba efflux after 30 mins by flow cytometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50496868(CHEMBL3220345)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of P-gp overexpressed in human 12D7-MDR cells assessed as inhibition of calcein-AM efflux after 30 mins by flow cytometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50496871(CHEMBL3220344)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of P-gp overexpressed in human 12D7-MDR cells assessed as inhibition of NBD-Aba efflux after 30 mins by flow cytometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50496871(CHEMBL3220344)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of P-gp overexpressed in human 12D7-MDR cells assessed as inhibition of calcein-AM efflux after 30 mins by flow cytometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50496868(CHEMBL3220345)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of P-gp in human CMEC/D3 cells assessed as inhibition of NBD-Aba efflux after 30 mins by flow cytometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50496871(CHEMBL3220344)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of P-gp in human CMEC/D3 cells assessed as inhibition of NBD-Aba efflux after 30 mins by flow cytometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50496872(CHEMBL3220343)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibition of P-gp in human CMEC/D3 cells assessed as inhibition of NBD-Aba efflux after 30 mins by flow cytometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50496872(CHEMBL3220343)
Affinity DataIC50:  7.70E+3nMAssay Description:Inhibition of P-gp overexpressed in human 12D7-MDR cells assessed as inhibition of calcein-AM efflux after 30 mins by flow cytometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50496872(CHEMBL3220343)
Affinity DataIC50:  1.05E+4nMAssay Description:Inhibition of P-gp overexpressed in human 12D7-MDR cells assessed as inhibition of NBD-Aba efflux after 30 mins by flow cytometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50496869(CHEMBL3220342)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition of P-gp overexpressed in human 12D7-MDR cells assessed as inhibition of calcein-AM efflux after 30 mins by flow cytometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50366816(ABACAVIR | Epzicom | Ziagen)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of P-gp in human CMEC/D3 cells assessed as inhibition of NBD-Aba efflux after 30 mins by flow cytometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50366816(ABACAVIR | Epzicom | Ziagen)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of P-gp overexpressed in human 12D7-MDR cells assessed as inhibition of calcein-AM efflux after 30 mins by flow cytometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50366816(ABACAVIR | Epzicom | Ziagen)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of P-gp overexpressed in human 12D7-MDR cells assessed as inhibition of NBD-Aba efflux after 30 mins by flow cytometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed