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Found 30 Enz. Inhib. hit(s) with all data for entry = 50009025
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
National University Of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM21393(7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-o...)
Affinity DataKi:  0.180nMAssay Description:Displacement of [3H]OH-DPAT from human recombinant 5-HT1A receptor measured after 60 mins by scintillation counter methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
National University Of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM21395(3-(2-(4-(4-Fluorobenzoyl)piperidinol)ethyl)-2,4(1H...)
Affinity DataKi:  0.450nMAssay Description:Displacement of [3H] ketanserin from human recombinant 5-HT2A receptor measured after 60 mins by scintillation counter methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
National University Of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50010859(CHEMBL11 | IMIPRAMINE HYDROCHLORIDE | IMIPRAMINE P...)
Affinity DataKi:  1.90nMAssay Description:Displacement of [3H] imipramine from human recombinant 5-HT transporter measured after 60 mins by scintillation counter methodMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
National University Of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50024204(1H-imidazo[4,5-c]pyridine derivative | 2N-[4,7-dim...)
Affinity DataKi:  2.80nMAssay Description:Antagonist activity at human recombinant 5-HT2B receptor in CHOK1 cells measured after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-K receptor(Homo sapiens (Human))
National University Of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50524648(CHEMBL4579120)
Affinity DataKi:  140nMAssay Description:Displacement of [125I]NKA from human recombinant NK2 receptor measured after 60 mins by scintillation counter methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
National University Of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50524648(CHEMBL4579120)
Affinity DataKi:  310nMAssay Description:Displacement of [3H]OH-DPAT from human recombinant 5-HT1A receptor measured after 60 mins by scintillation counter methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
National University Of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50524649(CHEMBL4562303)
Affinity DataKi:  420nMAssay Description:Displacement of [3H]OH-DPAT from human recombinant 5-HT1A receptor measured after 60 mins by scintillation counter methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
National University Of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50524648(CHEMBL4579120)
Affinity DataKi:  870nMAssay Description:Antagonist activity at human recombinant 5-HT2B receptor in CHOK1 cells measured after 30 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
National University Of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50524648(CHEMBL4579120)
Affinity DataKi:  970nMAssay Description:Displacement of [3H] ketanserin from human recombinant 5-HT2A receptor measured after 60 mins by scintillation counter methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSubstance-K receptor(Homo sapiens (Human))
National University Of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50524649(CHEMBL4562303)
Affinity DataKi:  1.60E+3nMAssay Description:Displacement of [125I]NKA from human recombinant NK2 receptor measured after 60 mins by scintillation counter methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
National University Of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50524648(CHEMBL4579120)
Affinity DataKi:  3.40E+3nMAssay Description:Displacement of [3H] imipramine from human recombinant 5-HT transporter measured after 60 mins by scintillation counter methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
National University Of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50524649(CHEMBL4562303)
Affinity DataKi:  4.70E+3nMAssay Description:Displacement of [3H] ketanserin from human recombinant 5-HT2A receptor measured after 60 mins by scintillation counter methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
National University Of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50524649(CHEMBL4562303)
Affinity DataKi:  8.20E+3nMAssay Description:Antagonist activity at human recombinant 5-HT2B receptor in CHOK1 cells measured after 30 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
National University Of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50524649(CHEMBL4562303)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H] imipramine from human recombinant 5-HT transporter measured after 60 mins by scintillation counter methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
National University Of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50524648(CHEMBL4579120)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H] mesulergine from human recombinant 5-HT2C receptor measured after 120 mins by scintillation counter methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
National University Of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM21393(7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-o...)
Affinity DataIC50:  0.280nMAssay Description:Displacement of [3H]OH-DPAT from human recombinant 5-HT1A receptor measured after 60 mins by scintillation counter methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
National University Of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM21395(3-(2-(4-(4-Fluorobenzoyl)piperidinol)ethyl)-2,4(1H...)
Affinity DataIC50:  0.820nMAssay Description:Displacement of [3H] ketanserin from human recombinant 5-HT2A receptor measured after 60 mins by scintillation counter methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
National University Of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50010859(CHEMBL11 | IMIPRAMINE HYDROCHLORIDE | IMIPRAMINE P...)
Affinity DataIC50:  4.10nMAssay Description:Displacement of [3H] imipramine from human recombinant 5-HT transporter measured after 60 mins by scintillation counter methodMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
National University Of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50024204(1H-imidazo[4,5-c]pyridine derivative | 2N-[4,7-dim...)
Affinity DataIC50:  5.20nMAssay Description:Antagonist activity at human recombinant 5-HT2B receptor in CHOK1 cells measured after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-K receptor(Homo sapiens (Human))
National University Of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50524648(CHEMBL4579120)
Affinity DataIC50:  260nMAssay Description:Displacement of [125I]NKA from human recombinant NK2 receptor measured after 60 mins by scintillation counter methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
National University Of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50524648(CHEMBL4579120)
Affinity DataIC50:  490nMAssay Description:Displacement of [3H]OH-DPAT from human recombinant 5-HT1A receptor measured after 60 mins by scintillation counter methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
National University Of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50524649(CHEMBL4562303)
Affinity DataIC50:  680nMAssay Description:Displacement of [3H]OH-DPAT from human recombinant 5-HT1A receptor measured after 60 mins by scintillation counter methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
National University Of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50524648(CHEMBL4579120)
Affinity DataIC50:  1.60E+3nMAssay Description:Antagonist activity at human recombinant 5-HT2B receptor in CHOK1 cells measured after 30 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
National University Of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50524648(CHEMBL4579120)
Affinity DataIC50:  1.80E+3nMAssay Description:Displacement of [3H] ketanserin from human recombinant 5-HT2A receptor measured after 60 mins by scintillation counter methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSubstance-K receptor(Homo sapiens (Human))
National University Of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50524649(CHEMBL4562303)
Affinity DataIC50:  3.00E+3nMAssay Description:Displacement of [125I]NKA from human recombinant NK2 receptor measured after 60 mins by scintillation counter methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
National University Of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50524648(CHEMBL4579120)
Affinity DataIC50:  7.40E+3nMAssay Description:Displacement of [3H] imipramine from human recombinant 5-HT transporter measured after 60 mins by scintillation counter methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
National University Of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50524649(CHEMBL4562303)
Affinity DataIC50:  8.70E+3nMAssay Description:Displacement of [3H] ketanserin from human recombinant 5-HT2A receptor measured after 60 mins by scintillation counter methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
National University Of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50524649(CHEMBL4562303)
Affinity DataIC50:  1.50E+4nMAssay Description:Antagonist activity at human recombinant 5-HT2B receptor in CHOK1 cells measured after 30 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
National University Of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50524649(CHEMBL4562303)
Affinity DataIC50: >1.00E+5nMAssay Description:Displacement of [3H] imipramine from human recombinant 5-HT transporter measured after 60 mins by scintillation counter methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
National University Of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50524648(CHEMBL4579120)
Affinity DataIC50: >1.00E+5nMAssay Description:Displacement of [3H] mesulergine from human recombinant 5-HT2C receptor measured after 120 mins by scintillation counter methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed