BindingDB PrimarySearch

Found 2 Enz. Inhib. hit(s) with all data for entry = 50013447

NACHT, LRR and PYD domains-containing protein 3(Mus musculus)
Zhejiang Chinese Medical University

Curated by ChEMBL

IC50: 7.5nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed mouse bone marrow derived macrophages assessed as reduction in IL-1beta level preincubated ...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
GoogleScholar

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PC cid PC sid PDB Similars

Details Article PubMed

NACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Zhejiang Chinese Medical University

Curated by ChEMBL

BDBM50155926(CHEMBL3183703)

IC50: 8.10nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human monocyte derived macrophages assessed as reduction in IL-1beta level preincubated for...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Purchase CHEMBL MCE
PC cid PC sid PDB Similars

Details Article PubMed PDB

3D Structure (crystal)