Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for assayid = 3 entry = 8423
TargetReceptor-type tyrosine-protein kinase FLT3 [K663Q](Human)
Cancer Research Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 247371BDBM247371(US9447092, 1)
Affinity DataKd:  5.10nMAssay Description:The kinase selectivity was assessed by profiling Example 1 in a 442-kinase panel (386 non-mutant kinases) at a concentration of 1 μM using the K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2017
Entry Details
US Patent

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Cancer Research Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 247371BDBM247371(US9447092, 1)
Affinity DataKd:  6.20nMAssay Description:The kinase selectivity was assessed by profiling Example 1 in a 442-kinase panel (386 non-mutant kinases) at a concentration of 1 μM using the K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2017
Entry Details
US Patent

TargetAurora kinase A(Human)
Cancer Research Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 247371BDBM247371(US9447092, 1)
Affinity DataKd:  7.5nMAssay Description:The kinase selectivity was assessed by profiling Example 1 in a 442-kinase panel (386 non-mutant kinases) at a concentration of 1 μM using the K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2017
Entry Details
US Patent

TargetReceptor-type tyrosine-protein kinase FLT3 [D835H](Human)
Cancer Research Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 247371BDBM247371(US9447092, 1)
Affinity DataKd:  11nMAssay Description:The kinase selectivity was assessed by profiling Example 1 in a 442-kinase panel (386 non-mutant kinases) at a concentration of 1 μM using the K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2017
Entry Details
US Patent

TargetReceptor-type tyrosine-protein kinase FLT3 [D835Y](Human)
Cancer Research Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 247371BDBM247371(US9447092, 1)
Affinity DataKd:  14nMAssay Description:The kinase selectivity was assessed by profiling Example 1 in a 442-kinase panel (386 non-mutant kinases) at a concentration of 1 μM using the K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2017
Entry Details
US Patent

TargetReceptor-type tyrosine-protein kinase FLT3 [N841I](Human)
Cancer Research Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 247371BDBM247371(US9447092, 1)
Affinity DataKd:  16nMAssay Description:The kinase selectivity was assessed by profiling Example 1 in a 442-kinase panel (386 non-mutant kinases) at a concentration of 1 μM using the K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2017
Entry Details
US Patent

TargetAurora kinase B(Human)
Cancer Research Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 247371BDBM247371(US9447092, 1)
Affinity DataKd:  48nMAssay Description:The kinase selectivity was assessed by profiling Example 1 in a 442-kinase panel (386 non-mutant kinases) at a concentration of 1 μM using the K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2017
Entry Details
US Patent

TargetReceptor-type tyrosine-protein kinase FLT3 [R834Q](Human)
Cancer Research Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 247371BDBM247371(US9447092, 1)
Affinity DataKd:  110nMAssay Description:The kinase selectivity was assessed by profiling Example 1 in a 442-kinase panel (386 non-mutant kinases) at a concentration of 1 μM using the K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2017
Entry Details
US Patent