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Report error Found 24 of ph data with Target = 'Cyclin-dependent kinase 7'
TargetCyclin-dependent kinase 7(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 31085BDBM31085(cid_11409972 | 1-[4-[(4-ethylpiperazin-1-yl)methyl...)
Affinity DataKd:  4.5nMpH: 7.4 T: 2°CAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2009
Entry Details
PCBioAssay
TargetCyclin-dependent kinase 7(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 31099BDBM31099(CHEMBL45741 | Flavopiridol | cid_24867231 | 2-(2-c...)
Affinity DataKd:  23nMpH: 7.4 T: 2°CAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2009
Entry Details
PCBioAssay
TargetCyclin-dependent kinase 7(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 5931BDBM5931(cid_3025986 | CHEMBL296468 | N-(5-{[(5-tert-butyl-...)
Affinity DataKd:  31nMpH: 7.4 T: 2°CAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2009
Entry Details
PCBioAssay
TargetCyclin-dependent kinase 7(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 31096BDBM31096(CHEMBL290084 | Staurosporine | cid_451705 | US2024...)
Affinity DataKd:  45nMpH: 7.4 T: 2°CAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2009
Entry Details
PCBioAssay
TargetCyclin-dependent kinase 7(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 16673BDBM16673(BAY439006 | CHEMBL1336 | BAY 43-9006 | 4-[4-({[4-c...)
Affinity DataKd:  140nMpH: 7.4 T: 2°CAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2009
Entry Details
PCBioAssay
TargetCyclin-dependent kinase 7(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 4814BDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataKd:  330nMpH: 7.4 T: 2°CAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2009
Entry Details
PCBioAssay
TargetCyclin-dependent kinase 7(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 50358212BDBM50358212(CHEMBL1922218 | US8846696, (2S3R)-3-{9-Isopropyl-6...)
Affinity DataIC50: 500nMpH: 7.4Assay Description:The compounds from the examples below were investigated for their CDK2/cyclin E, CDK1/cyclin B, CDK4/cyclin D1 and CDK7/cyclin H, ERK-2, and PKA inhi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
US Patent

TargetCyclin-dependent kinase 7(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 6866BDBM6866(1-Acyl-1H-[1,2,4]triazole-3,5-diamine Analogue 3b ...)
Affinity DataKd:  760nMpH: 7.4 T: 2°CAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2009
Entry Details
PCBioAssay
TargetCyclin-dependent kinase 7(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 31095BDBM31095(5-[(Z)-(5-fluoranyl-2-oxidanylidene-1H-indol-3-yli...)
Affinity DataKd:  930nMpH: 7.4 T: 2°CAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2009
Entry Details
PCBioAssay
TargetCyclin-dependent kinase 7(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 50358221BDBM50358221(CHEMBL1922120 | US8846696, (3RS,4R)-4-{9-Isopropyl...)
Affinity DataIC50: 1.10E+3nMpH: 7.4Assay Description:The compounds from the examples below were investigated for their CDK2/cyclin E, CDK1/cyclin B, CDK4/cyclin D1 and CDK7/cyclin H, ERK-2, and PKA inhi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
US Patent

TargetCyclin-dependent kinase 7(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 50358213BDBM50358213(CHEMBL1922219 | US8846696, (2R3S)-3-{9-Isopropyl-6...)
Affinity DataIC50: 1.30E+3nMpH: 7.4Assay Description:The compounds from the examples below were investigated for their CDK2/cyclin E, CDK1/cyclin B, CDK4/cyclin D1 and CDK7/cyclin H, ERK-2, and PKA inhi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
US Patent

TargetCyclin-dependent kinase 7(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 50358235BDBM50358235(CHEMBL1922209 | US8846696, (3RS,4S)-4-{9-Isopropyl...)
Affinity DataIC50: 1.50E+3nMpH: 7.4Assay Description:The compounds from the examples below were investigated for their CDK2/cyclin E, CDK1/cyclin B, CDK4/cyclin D1 and CDK7/cyclin H, ERK-2, and PKA inhi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
US Patent

TargetCyclin-dependent kinase 7(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 50358223BDBM50358223(CHEMBL1922122 | US8846696, (3RS,4R)-4-{9-Isopropyl...)
Affinity DataIC50: 1.60E+3nMpH: 7.4Assay Description:The compounds from the examples below were investigated for their CDK2/cyclin E, CDK1/cyclin B, CDK4/cyclin D1 and CDK7/cyclin H, ERK-2, and PKA inhi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
US Patent

TargetCyclin-dependent kinase 7(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 7533BDBM7533(2,6,9-Trisubstituted purine deriv. 28 | (2R)-2-[[6...)
Affinity DataKd:  1.80E+3nMpH: 7.4 T: 2°CAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2009
Entry Details
PCBioAssay
TargetCyclin-dependent kinase 7(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 50358222BDBM50358222(CHEMBL1922121 | US8846696, (3RS,4R)-4-{9-Isopropyl...)
Affinity DataIC50: 2.20E+3nMpH: 7.4Assay Description:The compounds from the examples below were investigated for their CDK2/cyclin E, CDK1/cyclin B, CDK4/cyclin D1 and CDK7/cyclin H, ERK-2, and PKA inhi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
US Patent

TargetCyclin-dependent kinase 7(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 50358211BDBM50358211(CHEMBL1922212 | US8846696, (3S)-3-{9-Isopropyl-6-[...)
Affinity DataIC50: 2.50E+3nMpH: 7.4Assay Description:The compounds from the examples below were investigated for their CDK2/cyclin E, CDK1/cyclin B, CDK4/cyclin D1 and CDK7/cyclin H, ERK-2, and PKA inhi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
US Patent

TargetCyclin-dependent kinase 7(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 25118BDBM25118(4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1H-...)
Affinity DataKd:  2.60E+3nMpH: 7.4 T: 2°CAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2009
Entry Details
PCBioAssay
TargetCyclin-dependent kinase 7(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 21079BDBM21079(1-[4-(3-azanyl-1H-indazol-4-yl)phenyl]-3-(2-fluora...)
Affinity DataKd:  2.90E+3nMpH: 7.4 T: 2°CAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2009
Entry Details
PCBioAssay
TargetCyclin-dependent kinase 7(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 50358210BDBM50358210(CHEMBL1922123 | US8846696, (3R)-3-{9-Isopropyl-6-[...)
Affinity DataIC50: 3.10E+3nMpH: 7.4Assay Description:The compounds from the examples below were investigated for their CDK2/cyclin E, CDK1/cyclin B, CDK4/cyclin D1 and CDK7/cyclin H, ERK-2, and PKA inhi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
US Patent

TargetCyclin-dependent kinase 7(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 50358237BDBM50358237(CHEMBL1922211 | US8846696, (3RS,4S)-4-{9-Isopropyl...)
Affinity DataIC50: 3.50E+3nMpH: 7.4Assay Description:The compounds from the examples below were investigated for their CDK2/cyclin E, CDK1/cyclin B, CDK4/cyclin D1 and CDK7/cyclin H, ERK-2, and PKA inhi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
US Patent

TargetCyclin-dependent kinase 7(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 50358236BDBM50358236(CHEMBL1922210 | US8846696, (3RS,4S)-4-{9-Isopropyl...)
Affinity DataIC50: 3.50E+3nMpH: 7.4Assay Description:The compounds from the examples below were investigated for their CDK2/cyclin E, CDK1/cyclin B, CDK4/cyclin D1 and CDK7/cyclin H, ERK-2, and PKA inhi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
US Patent

TargetCyclin-dependent kinase 7(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 164883BDBM164883(US9067888, 33)
Affinity DataIC50: 5.00E+3nMpH: 7.5Assay Description:In vitro kinase assay analysis may be performed using standard techniques described in the art. These techniques are also used by commercial services...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent

TargetCyclin-dependent kinase 7(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 164884BDBM164884(US9067888, 34)
Affinity DataIC50: 5.00E+3nMpH: 7.5Assay Description:In vitro kinase assay analysis may be performed using standard techniques described in the art. These techniques are also used by commercial services...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent

TargetCyclin-dependent kinase 7(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 26300BDBM26300(cid_16007391 | 2-{3-[(7-{3-[ethyl(2-hydroxyethyl)a...)
Affinity DataKd:  6.20E+3nMpH: 7.4 T: 2°CAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2009
Entry Details
PCBioAssay