TargetSphingomyelin phosphodiesterase 2(Homo sapiens (Human))
Tokyo University Of Pharmacy & Life Science
Curated by ChEMBL
Tokyo University Of Pharmacy & Life Science
Curated by ChEMBL
Affinity DataKi: 1.60E+3nMAssay Description:Inhibitory activity of the compound against schyphostatin of neutral sphingomyelinase (N-SMase) from bovine brain microsomeMore data for this Ligand-Target Pair
Affinity DataKi: 2.00E+4nMAssay Description:Negative log concentration of antagonist was determined on 5-hydroxytryptamine 2B receptor of Rat stomach fundusMore data for this Ligand-Target Pair
TargetSphingomyelin phosphodiesterase 2(Homo sapiens (Human))
Tokyo University Of Pharmacy & Life Science
Curated by ChEMBL
Tokyo University Of Pharmacy & Life Science
Curated by ChEMBL
Affinity DataKi: 2.53E+5nMAssay Description:Inhibitory activity against neutral sphingomyelinase (N-SMase) from bovine brain microsomesMore data for this Ligand-Target Pair
TargetSphingomyelin phosphodiesterase 2(Homo sapiens (Human))
Tokyo University Of Pharmacy & Life Science
Curated by ChEMBL
Tokyo University Of Pharmacy & Life Science
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Functional potency against Tachykinin receptor 2 (NK2) in rabbit pulmonary artery assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory concentration against neutral sphingomyelinase (N-Smase) from rat brain microsomesMore data for this Ligand-Target Pair
TargetSphingomyelin phosphodiesterase 2(Homo sapiens (Human))
Tokyo University Of Pharmacy & Life Science
Curated by ChEMBL
Tokyo University Of Pharmacy & Life Science
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity of the compound against neutral sphingomyelinase (N-SMase) from bovine brain microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory concentration against the membrane neutral magnesium-dependent Sphingomyelinase (N-SMase) using rat brain microsomes as the enzyme sourceMore data for this Ligand-Target Pair
TargetSphingomyelin phosphodiesterase 2(Homo sapiens (Human))
Tokyo University Of Pharmacy & Life Science
Curated by ChEMBL
Tokyo University Of Pharmacy & Life Science
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity of the compound against neutral sphingomyelinase (N-SMase) from bovine brain microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Negative log concentration of antagonist on 5-hydroxytryptamine 2A receptor in rat thoracic aortaMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Functional potency against Tachykinin receptor 2 (NK2) in rabbit pulmonary artery assayMore data for this Ligand-Target Pair
TargetSphingomyelin phosphodiesterase 2(Homo sapiens (Human))
Tokyo University Of Pharmacy & Life Science
Curated by ChEMBL
Tokyo University Of Pharmacy & Life Science
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Functional potency against Tachykinin receptor 2 (NK2) in rabbit pulmonary artery assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+3nMAssay Description:Negative log concentration of antagonist was determined on 5-hydroxytryptamine 2B receptor of Rat stomach fundusMore data for this Ligand-Target Pair
TargetSphingomyelin phosphodiesterase 2(Homo sapiens (Human))
Tokyo University Of Pharmacy & Life Science
Curated by ChEMBL
Tokyo University Of Pharmacy & Life Science
Curated by ChEMBL
Affinity DataIC50: 1.80E+3nMAssay Description:Negative log concentration of antagonist was determined on 5-hydroxytryptamine 2B receptor of Rat stomach fundusMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibitory concentration against the membrane neutral magnesium-dependent Sphingomyelinase (N-SMase) using rat brain microsomes as the enzyme sourceMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibitory concentration against the membrane neutral magnesium-dependent Sphingomyelinase (N-SMase) using rat brain microsomes as the enzyme sourceMore data for this Ligand-Target Pair
TargetSphingomyelin phosphodiesterase 2(Homo sapiens (Human))
Tokyo University Of Pharmacy & Life Science
Curated by ChEMBL
Tokyo University Of Pharmacy & Life Science
Curated by ChEMBL
Affinity DataIC50: 2.80E+3nMAssay Description:Negative log concentration of antagonist on 5-hydroxytryptamine 2A receptor in rat thoracic aortaMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibitory activity against N-SMase (neutral magnesium- dependent-sphingomyelinase) using rat brain microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+3nMAssay Description:Negative log concentration of antagonist was determined on 5-hydroxytryptamine 2B receptor of Rat stomach fundusMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibitory concentration against the membrane neutral magnesium-dependent Sphingomyelinase (N-SMase) using rat brain microsomes as the enzyme sourceMore data for this Ligand-Target Pair
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibitory activity against N-SMase (neutral magnesium- dependent-sphingomyelinase) using rat brain microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibitory concentration against the membrane neutral magnesium-dependent Sphingomyelinase (N-SMase) using rat brain microsomes as the enzyme sourceMore data for this Ligand-Target Pair
Affinity DataIC50: 4.20E+3nMAssay Description:Negative log concentration of antagonist on 5-hydroxytryptamine 2A receptor in rat thoracic aortaMore data for this Ligand-Target Pair
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibitory concentration against the membrane neutral magnesium-dependent Sphingomyelinase (N-SMase) using rat brain microsomes as the enzyme sourceMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Negative log concentration of antagonist on 5-hydroxytryptamine 2A receptor in rat thoracic aortaMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibitory concentration against the membrane neutral magnesium-dependent Sphingomyelinase (N-SMase) using rat brain microsomes as the enzyme sourceMore data for this Ligand-Target Pair
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibitory activity against N-SMase (neutral magnesium- dependent-sphingomyelinase) using rat brain microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibitory activity against N-SMase (neutral magnesium- dependent-sphingomyelinase) using rat brain microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibitory concentration against the membrane neutral magnesium-dependent Sphingomyelinase (N-SMase) using rat brain microsomes as the enzyme sourceMore data for this Ligand-Target Pair
Affinity DataIC50: 8.20E+3nMAssay Description:Negative log concentration of antagonist on 5-hydroxytryptamine 2A receptor in rat thoracic aortaMore data for this Ligand-Target Pair
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibitory concentration against the membrane neutral magnesium-dependent Sphingomyelinase (N-SMase) using rat brain microsomes as the enzyme sourceMore data for this Ligand-Target Pair
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibitory concentration against the membrane neutral magnesium-dependent Sphingomyelinase (N-SMase) using rat brain microsomes as the enzyme sourceMore data for this Ligand-Target Pair
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibitory concentration against the membrane neutral magnesium-dependent Sphingomyelinase (N-SMase) using rat brain microsomes as the enzyme sourceMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+4nMAssay Description:Negative log concentration of antagonist was determined on 5-hydroxytryptamine 2B receptor of Rat stomach fundusMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+4nMAssay Description:Negative log concentration of antagonist on 5-hydroxytryptamine 2A receptor in rat thoracic aortaMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibitory concentration against the membrane neutral magnesium-dependent Sphingomyelinase (N-SMase) using rat brain microsomes as the enzyme sourceMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibitory activity against N-SMase (neutral magnesium- dependent-sphingomyelinase) using rat brain microsomesMore data for this Ligand-Target Pair
TargetSphingomyelin phosphodiesterase 2(Homo sapiens (Human))
Tokyo University Of Pharmacy & Life Science
Curated by ChEMBL
Tokyo University Of Pharmacy & Life Science
Curated by ChEMBL
Affinity DataIC50: 2.59E+4nMAssay Description:Inhibitory activity against NSMase (neutral sphingomyelinase)More data for this Ligand-Target Pair
TargetSphingomyelin phosphodiesterase 2(Homo sapiens (Human))
Tokyo University Of Pharmacy & Life Science
Curated by ChEMBL
Tokyo University Of Pharmacy & Life Science
Curated by ChEMBL
Affinity DataIC50: 2.77E+4nMAssay Description:Inhibitory activity against NSMase (neutral sphingomyelinase)More data for this Ligand-Target Pair
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibitory concentration against the membrane neutral magnesium-dependent Sphingomyelinase (N-SMase) using rat brain microsomes as the enzyme sourceMore data for this Ligand-Target Pair
Affinity DataIC50: 3.40E+4nMAssay Description:Negative log concentration of antagonist was determined on 5-hydroxytryptamine 2B receptor of Rat stomach fundusMore data for this Ligand-Target Pair
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibitory activity against N-SMase (neutral magnesium- dependent-sphingomyelinase) using rat brain microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 4.93E+4nMAssay Description:Inhibitory concentration against lysosomal neutral sphingomyelinase (N-Smase)More data for this Ligand-Target Pair
Affinity DataIC50: 5.80E+4nMAssay Description:Inhibitory activity against N-SMase (neutral magnesium- dependent-sphingomyelinase) using rat brain microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 7.70E+4nMAssay Description:Inhibitory concentration against the membrane neutral magnesium-dependent Sphingomyelinase (N-SMase) using rat brain microsomes as the enzyme sourceMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory concentration against the membrane neutral magnesium-dependent Sphingomyelinase (N-SMase) using rat brain microsomes as the enzyme sourceMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory concentration against the membrane neutral magnesium-dependent Sphingomyelinase (N-SMase) using rat brain microsomes as the enzyme sourceMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory concentration against the membrane neutral magnesium-dependent Sphingomyelinase (N-SMase) using rat brain microsomes as the enzyme sourceMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of nSMase in rat brain microsomal homogenate by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of nSMase in rat brain microsomal homogenate by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of nSMase in rat brain microsomal homogenate by fluorescence assayMore data for this Ligand-Target Pair