TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research
Curated by ChEMBL
Johnson Matthey Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Binding affinity towards fMLF receptor using human neutrophilsMore data for this Ligand-Target Pair
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research
Curated by ChEMBL
Johnson Matthey Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Binding affinity towards fMLF receptor using human neutrophilsMore data for this Ligand-Target Pair
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research
Curated by ChEMBL
Johnson Matthey Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Binding affinity towards fMLF receptor using human neutrophilsMore data for this Ligand-Target Pair
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research
Curated by ChEMBL
Johnson Matthey Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Antagonist activity at human recombinant FPR1 in expressed in HEK293 cells assessed as inhibition of FMLP-stimulated intracellular calcium mobilisati...More data for this Ligand-Target Pair
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research
Curated by ChEMBL
Johnson Matthey Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Antagonist activity at human FPR1 in human neutrophils assessed as inhibition of fMLF-stimulated intracellular calcium mobilisation by FLIPR assayMore data for this Ligand-Target Pair
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research
Curated by ChEMBL
Johnson Matthey Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Antagonistic activity was determined by measuring the ability to inhibit superoxide production(stimulated by fMLF) using human neutrophilsMore data for this Ligand-Target Pair
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research
Curated by ChEMBL
Johnson Matthey Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Binding affinity towards fMLF receptor using human neutrophilsMore data for this Ligand-Target Pair
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research
Curated by ChEMBL
Johnson Matthey Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Binding affinity towards fMLF receptor using human neutrophilsMore data for this Ligand-Target Pair
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research
Curated by ChEMBL
Johnson Matthey Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Antagonist activity at human recombinant FPR1 in expressed in HEK293 cells assessed as inhibition of FMLP-stimulated intracellular calcium mobilisati...More data for this Ligand-Target Pair
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research
Curated by ChEMBL
Johnson Matthey Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Antagonist activity at human FPR1 in human neutrophils assessed as inhibition of fMLF-stimulated intracellular calcium mobilisation by FLIPR assayMore data for this Ligand-Target Pair
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research
Curated by ChEMBL
Johnson Matthey Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Antagonist activity at human FPR1 in human neutrophils assessed as inhibition of fMLF-stimulated intracellular calcium mobilisation by FLIPR assayMore data for this Ligand-Target Pair
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research
Curated by ChEMBL
Johnson Matthey Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Binding affinity towards fMLF receptor using human neutrophilsMore data for this Ligand-Target Pair
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research
Curated by ChEMBL
Johnson Matthey Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Antagonist activity at human recombinant FPR1 in expressed in HEK293 cells assessed as inhibition of FMLP-stimulated intracellular calcium mobilisati...More data for this Ligand-Target Pair
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research
Curated by ChEMBL
Johnson Matthey Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Antagonist activity at human recombinant FPR1 in expressed in HEK293 cells assessed as inhibition of FMLP-stimulated intracellular calcium mobilisati...More data for this Ligand-Target Pair
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research
Curated by ChEMBL
Johnson Matthey Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Binding affinity towards fMLF receptor using human neutrophilsMore data for this Ligand-Target Pair
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research
Curated by ChEMBL
Johnson Matthey Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 79nMAssay Description:Antagonist activity at human recombinant FPR1 in expressed in HEK293 cells assessed as inhibition of FMLP-stimulated intracellular calcium mobilisati...More data for this Ligand-Target Pair
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research
Curated by ChEMBL
Johnson Matthey Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 79nMAssay Description:Antagonist activity at human FPR1 in human neutrophils assessed as inhibition of fMLF-stimulated intracellular calcium mobilisation by FLIPR assayMore data for this Ligand-Target Pair
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research
Curated by ChEMBL
Johnson Matthey Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 79nMAssay Description:Antagonist activity at human FPR1 in human neutrophils assessed as inhibition of fMLF-stimulated intracellular calcium mobilisation by FLIPR assayMore data for this Ligand-Target Pair
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research
Curated by ChEMBL
Johnson Matthey Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 79nMAssay Description:Antagonist activity at human recombinant FPR1 in expressed in HEK293 cells assessed as inhibition of FMLP-stimulated intracellular calcium mobilisati...More data for this Ligand-Target Pair
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research
Curated by ChEMBL
Johnson Matthey Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Antagonistic activity was determined by measuring the ability to inhibit superoxide production(stimulated by fMLF) using human neutrophilsMore data for this Ligand-Target Pair
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research
Curated by ChEMBL
Johnson Matthey Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Binding affinity towards fMLF receptor using human neutrophilsMore data for this Ligand-Target Pair
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research
Curated by ChEMBL
Johnson Matthey Biomedical Research
Curated by ChEMBL
Affinity DataIC50: <100nMAssay Description:Cyclic Adenosine Monophosphate (cAMP) Assay: CHO-K1 cells stably overexpressing hFPR1 were plated into 384-well cell culture plates (2,000/well/5 ...More data for this Ligand-Target Pair
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research
Curated by ChEMBL
Johnson Matthey Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 126nMAssay Description:Antagonist activity at human FPR1 in human neutrophils assessed as inhibition of fMLF-stimulated intracellular calcium mobilisation by FLIPR assayMore data for this Ligand-Target Pair
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research
Curated by ChEMBL
Johnson Matthey Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Antagonist activity at formyl peptide receptor in human HL60 cells assessed as inhibition of fMLP-induced calcium mobilization incubated for 5 mins p...More data for this Ligand-Target Pair
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research
Curated by ChEMBL
Johnson Matthey Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibitory activity against human formylpeptide receptor (FPR) of human leukemia HL-60 cellsMore data for this Ligand-Target Pair
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research
Curated by ChEMBL
Johnson Matthey Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 158nMAssay Description:Antagonist activity at FPR1 in human neutrophils assessed as inhibition of fMLF-stimulated degranulation after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research
Curated by ChEMBL
Johnson Matthey Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 158nMAssay Description:Antagonist activity at human FPR1 in human neutrophils assessed as inhibition of fMLF-stimulated intracellular calcium mobilisation by FLIPR assayMore data for this Ligand-Target Pair
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research
Curated by ChEMBL
Johnson Matthey Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 158nMAssay Description:Antagonist activity at human FPR1 in human neutrophils assessed as inhibition of fMLF-stimulated intracellular calcium mobilisation by FLIPR assayMore data for this Ligand-Target Pair
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research
Curated by ChEMBL
Johnson Matthey Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 158nMAssay Description:Antagonist activity at human recombinant FPR1 in expressed in HEK293 cells assessed as inhibition of FMLP-stimulated intracellular calcium mobilisati...More data for this Ligand-Target Pair
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research
Curated by ChEMBL
Johnson Matthey Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Antagonist activity at human recombinant FPR1 in expressed in HEK293 cells assessed as inhibition of FMLP-stimulated intracellular calcium mobilisati...More data for this Ligand-Target Pair
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research
Curated by ChEMBL
Johnson Matthey Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Binding affinity towards fMLF receptor using human neutrophilsMore data for this Ligand-Target Pair
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research
Curated by ChEMBL
Johnson Matthey Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Binding affinity towards fMLF receptor using human neutrophilsMore data for this Ligand-Target Pair
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research
Curated by ChEMBL
Johnson Matthey Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Binding affinity towards fMLF receptor using human neutrophilsMore data for this Ligand-Target Pair
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research
Curated by ChEMBL
Johnson Matthey Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Antagonistic activity was determined by measuring the ability to inhibit superoxide production(stimulated by fMLF) using human neutrophilsMore data for this Ligand-Target Pair
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research
Curated by ChEMBL
Johnson Matthey Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibitory activity against human formylpeptide receptor (FPR) of human leukemia HL-60 cellsMore data for this Ligand-Target Pair
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research
Curated by ChEMBL
Johnson Matthey Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Binding affinity towards fMLF receptor using human neutrophilsMore data for this Ligand-Target Pair
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research
Curated by ChEMBL
Johnson Matthey Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Binding affinity towards fMLF receptor using human neutrophilsMore data for this Ligand-Target Pair
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research
Curated by ChEMBL
Johnson Matthey Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 316nMAssay Description:Antagonist activity at human recombinant FPR1 in expressed in HEK293 cells assessed as inhibition of FMLP-stimulated intracellular calcium mobilisati...More data for this Ligand-Target Pair
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research
Curated by ChEMBL
Johnson Matthey Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 316nMAssay Description:Antagonist activity at human FPR1 in human neutrophils assessed as inhibition of fMLF-stimulated intracellular calcium mobilisation by FLIPR assayMore data for this Ligand-Target Pair
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research
Curated by ChEMBL
Johnson Matthey Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 316nMAssay Description:Antagonist activity at human recombinant FPR1 in expressed in HEK293 cells assessed as inhibition of FMLP-stimulated intracellular calcium mobilisati...More data for this Ligand-Target Pair
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research
Curated by ChEMBL
Johnson Matthey Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 398nMAssay Description:Antagonist activity at human FPR1 in human neutrophils assessed as inhibition of fMLF-stimulated intracellular calcium mobilisation by FLIPR assayMore data for this Ligand-Target Pair
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research
Curated by ChEMBL
Johnson Matthey Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 398nMAssay Description:Antagonist activity at human recombinant FPR1 in expressed in HEK293 cells assessed as inhibition of FMLP-stimulated intracellular calcium mobilisati...More data for this Ligand-Target Pair
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research
Curated by ChEMBL
Johnson Matthey Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 420nMAssay Description:Antagonist activity at formyl peptide receptor in human HL60 cells assessed as inhibition of fMLP-induced calcium mobilization incubated for 5 mins p...More data for this Ligand-Target Pair
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research
Curated by ChEMBL
Johnson Matthey Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph...More data for this Ligand-Target Pair
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research
Curated by ChEMBL
Johnson Matthey Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Antagonistic activity was determined by measuring the ability to inhibit superoxide production(stimulated by fMLF) using human neutrophilsMore data for this Ligand-Target Pair
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research
Curated by ChEMBL
Johnson Matthey Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Antagonistic activity was determined by measuring the ability to inhibit superoxide production(stimulated by fMLF) using human neutrophilsMore data for this Ligand-Target Pair
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research
Curated by ChEMBL
Johnson Matthey Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 501nMAssay Description:Antagonist activity at human FPR1 in human neutrophils assessed as inhibition of fMLF-stimulated intracellular calcium mobilisation by FLIPR assayMore data for this Ligand-Target Pair
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research
Curated by ChEMBL
Johnson Matthey Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 501nMAssay Description:Antagonist activity at human FPR1 in human neutrophils assessed as inhibition of fMLF-stimulated intracellular calcium mobilisation by FLIPR assayMore data for this Ligand-Target Pair
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research
Curated by ChEMBL
Johnson Matthey Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 501nMAssay Description:Antagonist activity at human FPR1 in human neutrophils assessed as inhibition of fMLF-stimulated intracellular calcium mobilisation by FLIPR assayMore data for this Ligand-Target Pair
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research
Curated by ChEMBL
Johnson Matthey Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 550nMAssay Description:Cyclic Adenosine Monophosphate (cAMP) Assay: CHO-K1 cells stably overexpressing hFPR1 were plated into 384-well cell culture plates (2,000/well/5 ...More data for this Ligand-Target Pair