Compile Data Set for Download or QSAR
maximum 50k data
Found 203 of ic50 data for polymerid = 50006783
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))TBA
LigandPNGBDBM50608631(CHEMBL5274434)
Affinity DataIC50:  2nMAssay Description:Inhibition of human recombinant ABHD6More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))TBA
LigandPNGBDBM50608632(CHEMBL4279328)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of human recombinant ABHD6More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))TBA
LigandPNGBDBM50211266(CHEMBL3906477)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of human ABHD6 using 2-AG as natural substrate by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))TBA
LigandPNGBDBM50211257(CHEMBL3895863 | US10583137, Compound 14)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of human ABHD6 using 2-AG as natural substrate by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))TBA
LigandPNGBDBM50211266(CHEMBL3906477)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of human recombinant ABHD6More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))TBA
LigandPNGBDBM50211257(CHEMBL3895863 | US10583137, Compound 14)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of human recombinant ABHD6More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))TBA
LigandPNGBDBM434879(US10583137, Compound 17 | tert-Butyl 3-benzyl-4-(4...)
Affinity DataIC50:  3.60nMAssay Description:Inhibition of human recombinant ABHD6More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))TBA
LigandPNGBDBM24567((2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-...)
Affinity DataIC50:  13nMAssay Description:Inhibition of human ABHD6 expressed in HEK293 cells at 1 uM pre-incubated for 10 mins before 2-AG substrate addition followed by rapid 40 fold compou...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))TBA
LigandPNGBDBM24567((2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-...)
Affinity DataIC50:  14nMAssay Description:Inhibition of human FAAH expressed in COS7 cell membranes pre-incubated for 10 mins before [3H]-AEA substrate addition by liquid scintillation counti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))TBA
LigandPNGBDBM50132713(Arachidonic acid derivative | CHEMBL113262 | Methy...)
Affinity DataIC50:  17nMAssay Description:Inhibition of ABHD6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))TBA
LigandPNGBDBM24567((2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human ABHD6 expressed in HEK293 cells at 1 uM pre-incubated for 10 mins before 2-AG substrate addition followed by rapid 40 fold compou...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))TBA
LigandPNGBDBM50211260(CHEMBL3964338)
Affinity DataIC50:  20nMAssay Description:Inhibition of human ABHD6 using 2-AG as natural substrate by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))TBA
LigandPNGBDBM50211269(CHEMBL3970032)
Affinity DataIC50:  25nMAssay Description:Inhibition of human ABHD6 using 2-AG as natural substrate by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))TBA
LigandPNGBDBM24567((2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-...)
Affinity DataIC50:  37nMAssay Description:Inhibition of human ABHD6 expressed in HEK293 cells at 1 uM pre-incubated for 10 mins before 2-AG substrate addition followed by rapid 40 fold compou...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))TBA
LigandPNGBDBM50211235(CHEMBL3974512)
Affinity DataIC50:  40nMAssay Description:Inhibition of human ABHD6 using 2-AG as natural substrate by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))TBA
LigandPNGBDBM50211236(CHEMBL2144065)
Affinity DataIC50:  40nMAssay Description:Inhibition of human ABHD6 using 2-AG as natural substrate by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))TBA
LigandPNGBDBM50211240(CHEMBL3897587)
Affinity DataIC50:  40nMAssay Description:Inhibition of human ABHD6 using 2-AG as natural substrate by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))TBA
LigandPNGBDBM50211275(CHEMBL3931744)
Affinity DataIC50:  40nMAssay Description:Inhibition of human ABHD6 using 2-AG as natural substrate by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))TBA
LigandPNGBDBM50608630(CHEMBL5284566)
Affinity DataIC50:  44nMAssay Description:Inhibition of human ABHD6 expressed in HEK293 cells using 1-AG as substrate incubated for 90 mins by sensitive fluorescence glycerol assayMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))TBA
LigandPNGBDBM50118167(CHEMBL3613671)
Affinity DataIC50:  44nMAssay Description:Inhibition of human ABHD6 expressed in HEK293 cells assessed as reduction in glycerol production from 1-AG hydrolysis pre-incubated for 30 mins befor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))TBA
LigandPNGBDBM24567((2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-...)
Affinity DataIC50:  48nMAssay Description:Inhibition of human ABHD6 containing pCMV6-AC-hABHD6 transfected into HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))TBA
LigandPNGBDBM24567((2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-...)
Affinity DataIC50:  48nMAssay Description:Inhibition of human ABHD6 expressed in HEK293 cells using TAMRA-FP as substrate by SDS-PAGE gel based competitive ABPP assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))TBA
LigandPNGBDBM50211271(CHEMBL3913807)
Affinity DataIC50:  50nMAssay Description:Inhibition of human ABHD6 using 2-AG as natural substrate by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))TBA
LigandPNGBDBM444416(US10662159, Example 1)
Affinity DataIC50:  55nMAssay Description:ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))TBA
LigandPNGBDBM444419(US10662159, Example 4)
Affinity DataIC50:  55nMAssay Description:ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))TBA
LigandPNGBDBM444423(US10662159, Example 8)
Affinity DataIC50:  55nMAssay Description:ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))TBA
LigandPNGBDBM444424(US10662159, Example 9)
Affinity DataIC50:  55nMAssay Description:ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))TBA
LigandPNGBDBM444431(US10662159, Example 16)
Affinity DataIC50:  55nMAssay Description:ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))TBA
LigandPNGBDBM444432(US10662159, Example 17)
Affinity DataIC50:  55nMAssay Description:ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))TBA
LigandPNGBDBM444434(US10662159, Example 19)
Affinity DataIC50:  55nMAssay Description:ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))TBA
LigandPNGBDBM444436(US10662159, Example 21)
Affinity DataIC50:  55nMAssay Description:ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))TBA
LigandPNGBDBM444437(US10662159, Example 22)
Affinity DataIC50:  55nMAssay Description:ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))TBA
LigandPNGBDBM444438(US10662159, Example 23)
Affinity DataIC50:  55nMAssay Description:ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))TBA
LigandPNGBDBM444440(US10662159, Example 25)
Affinity DataIC50:  55nMAssay Description:ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))TBA
LigandPNGBDBM444441(US10662159, Example 26)
Affinity DataIC50:  55nMAssay Description:ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))TBA
LigandPNGBDBM444445(US10662159, Example 30)
Affinity DataIC50:  55nMAssay Description:ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))TBA
LigandPNGBDBM444446(US10662159, Example 31)
Affinity DataIC50:  55nMAssay Description:ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))TBA
LigandPNGBDBM444447(US10662159, Example 32)
Affinity DataIC50:  55nMAssay Description:ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))TBA
LigandPNGBDBM444448(US10662159, Example 35)
Affinity DataIC50:  55nMAssay Description:ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))TBA
LigandPNGBDBM444451(US10662159, Example 39)
Affinity DataIC50:  55nMAssay Description:ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))TBA
LigandPNGBDBM444452(US10662159, Example 40)
Affinity DataIC50:  55nMAssay Description:ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))TBA
LigandPNGBDBM444453(US10662159, Example 41)
Affinity DataIC50:  55nMAssay Description:ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))TBA
LigandPNGBDBM444454(US10662159, Example 42)
Affinity DataIC50:  55nMAssay Description:ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))TBA
LigandPNGBDBM444455(US10662159, Example 43)
Affinity DataIC50:  55nMAssay Description:ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))TBA
LigandPNGBDBM444457(US10662159, Example 45)
Affinity DataIC50:  55nMAssay Description:ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))TBA
LigandPNGBDBM444458(US10662159, Example 46)
Affinity DataIC50:  55nMAssay Description:ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))TBA
LigandPNGBDBM444459(US10662159, Example 47)
Affinity DataIC50:  55nMAssay Description:ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))TBA
LigandPNGBDBM444460(US10662159, Example 48)
Affinity DataIC50:  55nMAssay Description:ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))TBA
LigandPNGBDBM444461(US10662159, Example 49)
Affinity DataIC50:  55nMAssay Description:ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))TBA
LigandPNGBDBM444462(US10662159, Example 50)
Affinity DataIC50:  55nMAssay Description:ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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